SNEV(Prp19/PSO4) deficiency increases PUVA-induced senescence in mouse skin

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Ubiquitous overexpression of the DNA repair factor dPrp19 reduces DNA damage and extends Drosophila life span SNEVhPrp19/hPso4 Regulates Adipogenesis of Human Adipose Stromal Cells.Ubiquitylation at the Fork: Making and Breaking Chains to Complete DNA Replication

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SNEV(Prp19/PSO4) deficiency increases PUVA-induced senescence in mouse skin

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SNEV(Prp19/PSO4) deficiency increases PUVA-induced senescence in mouse skin

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SNEV(Prp19/PSO4) deficiency increases PUVA-induced senescence in mouse skin

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SNEV(Prp19/PSO4) deficiency increases PUVA-induced senescence in mouse skin

@ast

SNEV(Prp19/PSO4) deficiency increases PUVA-induced senescence in mouse skin

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SNEV(Prp19/PSO4) deficiency increases PUVA-induced senescence in mouse skin

@ast

SNEV(Prp19/PSO4) deficiency increases PUVA-induced senescence in mouse skin

@en

P1476

SNEV(Prp19/PSO4) deficiency increases PUVA-induced senescence in mouse skin

@en

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Benjamin Mayerhofer

http://www.w3.org/2001/XMLSchema#string

Georg F Beilhack

http://www.w3.org/2001/XMLSchema#string

Hanna Dellago

http://www.w3.org/2001/XMLSchema#string

Regina Grillari-Voglauer

http://www.w3.org/2001/XMLSchema#string

Reginald Bittner

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Reinhard Grausenburger

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Rossella Monteforte

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DNA Damage, Aging, and Cancer

SNEV is an evolutionarily conserved splicing factor whose oligomerization is necessary for spliceosome assembly

PRP19 transforms into a sensor of RPA-ssDNA after DNA damage and drives ATR activation via a ubiquitin-mediated circuitry

Human Pso4 is a metnase (SETMAR)-binding partner that regulates metnase function in DNA repair

Cdc5L interacts with ATR and is required for the S-phase cell-cycle checkpoint

A biomarker that identifies senescent human cells in culture and in aging skin in vivo

Telomerase reactivation reverses tissue degeneration in aged telomerase-deficient mice.

Early embryonic lethality of mice lacking the essential protein SNEV

Role of human Pso4 in mammalian DNA repair and association with terminal deoxynucleotidyl transferase

The Prp19 complex directly functions in mitotic spindle assembly

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212-217

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scholarly article

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10.1111/EXD.12910

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P478

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2015-12-14T00:00:00Z

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287002473

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26663487

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4832318

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SNEV(Prp19/PSO4) deficiency increases PUVA-induced senescence in mouse skin

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P2860

P2860

SNEV(Prp19/PSO4) deficiency increases PUVA-induced senescence in mouse skin

description

name

type

label

prefLabel

P1433

P1476

P2093

P2860

P304

P31

P356

P433

P478

P50

P577

P5875

P698

P932

P356

P1433

P1476

P2093

P2860

P304

P31

P356

P433

P478

P50

P577

P5875

P698

P932