Osteopontin is a novel downstream target of SOX9 with diagnostic implications for progression of liver fibrosis in humans. - Test2 - elhamkhani - TriplyDB

Osteopontin is a novel downstream target of SOX9 with diagnostic implications for progression of liver fibrosis in humans.

Osteopontin is a novel downstream target of SOX9 with diagnostic implications for progression of liver fibrosis in humans.

http://www.wikidata.org/entity/Q36801010

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Role of Osteopontin in Liver Diseases MicroRNAs in liver fibrosis: Focusing on the interaction with hedgehog signaling Osteopontin-A Master Regulator of Epithelial-Mesenchymal Transition Extracellular matrix and liver disease HCV derived from sera of HCV-infected patients induces pro-fibrotic effects in human primary fibroblasts by activating GLI2 Osteopontin is up-regulated in chronic hepatitis C and is associated with cellular permissiveness for hepatitis C virus replication.New drug targets for alcoholic liver disease.Rhein, a natural anthraquinone derivative, attenuates the activation of pancreatic stellate cells and ameliorates pancreatic fibrosis in mice with experimental chronic pancreatitis.The versatile functions of Sox9 in development, stem cells, and human diseases Epimorphin alters the inhibitory effects of SOX9 on Mmp13 in activated hepatic stellate cells.Osteopontin neutralisation abrogates the liver progenitor cell response and fibrogenesis in mice MicroRNA125b-mediated Hedgehog signaling influences liver regeneration by chorionic plate-derived mesenchymal stem cells.MicroRNA-378 limits activation of hepatic stellate cells and liver fibrosis by suppressing Gli3 expression.SOX9 is targeted for proteasomal degradation by the E3 ligase FBW7 in response to DNA damage.Hepatic gene expression profiles differentiate presymptomatic patients with mild versus severe nonalcoholic fatty liver disease.Osteopontin: Versatile modulator of liver diseases.Hedgehog signaling pathway as key player in liver fibrosis: new insights and perspectives.Re-expression of pro-fibrotic, embryonic preserved mediators in irradiated arterial vessels of the head and neck region.Expression kinetics of hepatic progenitor markers in cellular models of human liver development recapitulating hepatocyte and biliary cell fate commitment.Molecular mechanisms of Sox transcription factors during the development of liver, bile duct, and pancreas.Activation of peroxisome proliferator activated receptor alpha ameliorates ethanol mediated liver fibrosis in mice.Hepatic stellate cells as key target in liver fibrosis.Bone marrow-derived monocyte infusion improves hepatic fibrosis by decreasing osteopontin, TGF-β1, IL-13 and oxidative stress.PAK proteins and YAP-1 signalling downstream of integrin beta-1 in myofibroblasts promote liver fibrosis.RNAi in murine hepatocytes: the agony of choice--a study of the influence of lipid-based transfection reagents on hepatocyte metabolism.Biliary fibrosis drives liver repopulation and phenotype transition of transplanted hepatocytes Osteopontin: a new player in regulating hepatic ductular reaction and hepatic progenitor cell responses during chronic liver injury.Liraglutide improves liver microvascular dysfunction in cirrhosis: Evidence from translational studies.SOX9 is a novel cancer stem cell marker surrogated by osteopontin in human hepatocellular carcinoma.Generation of functional cholangiocyte-like cells from human pluripotent stem cells and HepaRG cells.SOX9 predicts progression toward cirrhosis in patients while its loss protects against liver fibrosis.Notch signaling and progenitor/ductular reaction in steatohepatitis.Deficient TSC1/TSC2-complex suppression of SOX9-osteopontin-AKT signalling cascade constrains tumour growth in tuberous sclerosis complex.Role of canonical Hedgehog signaling pathway in liver

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Osteopontin is a novel downstream target of SOX9 with diagnostic implications for progression of liver fibrosis in humans.

http://www.wikidata.org/entity/Q36801010

description

2012 nî lūn-bûn

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2012年論文

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2012年论文

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2012年论文

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2012年论文

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Osteopontin is a novel downstr ...... n of liver fibrosis in humans.

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Osteopontin is a novel downstr ...... n of liver fibrosis in humans.

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Osteopontin is a novel downstr ...... n of liver fibrosis in humans.

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Osteopontin is a novel downstr ...... n of liver fibrosis in humans.

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Osteopontin is a novel downstr ...... n of liver fibrosis in humans.

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Osteopontin is a novel downstr ...... n of liver fibrosis in humans.

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Varinder Athwal

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P2860

A previously unidentified amino-terminal domain regulates transcriptional activity of wild-type and disease-associated human GLI2

Trps1, a regulator of chondrocyte proliferation and differentiation, interacts with the activator form of Gli3

A competitive transcription factor binding mechanism determines the timing of late cell cycle-dependent gene expression.

Gli proteins encode context-dependent positive and negative functions: implications for development and disease

Induction of sonic hedgehog mediators by transforming growth factor-beta: Smad3-dependent activation of Gli2 and Gli1 expression in vitro and in vivo

Osteopontin: role in cell signaling and cancer progression

Reduced sox9 function promotes heart valve calcification phenotypes in vivo

Sonic hedgehog signaling regulates Gli2 transcriptional activity by suppressing its processing and degradation

Hydroureternephrosis due to loss of Sox9-regulated smooth muscle cell differentiation of the ureteric mesenchyme

Six2 functions redundantly immediately downstream of Hoxa2

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10.1002/HEP.25758

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223970275

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22488688

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3638324

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