The MYST family of histone acetyltransferases and their intimate links to cancer.
about
Subunit composition and substrate specificity of a MOF-containing histone acetyltransferase distinct from the male-specific lethal (MSL) complexMolecular architecture of quartet MOZ/MORF histone acetyltransferase complexesEpigenetics: a molecular link between environmental factors and type 2 diabetesStudying epigenetic complexes and their inhibitors with the proteomics toolboxThe multifaceted role of lysine acetylation in cancer: prognostic biomarker and therapeutic targetThe Functional Analysis of Histone Acetyltransferase MOF in TumorigenesisOpen access chemical probes for epigenetic targetsKeep-ING balance: tumor suppression by epigenetic regulationMetabolism, longevity and epigeneticsMolecular functions of the histone acetyltransferase chaperone complex Rtt109-Vps75Eaf1 is the platform for NuA4 molecular assembly that evolutionarily links chromatin acetylation to ATP-dependent exchange of histone H2A variants.A PWWP domain-containing protein targets the NuA3 acetyltransferase complex via histone H3 lysine 36 trimethylation to coordinate transcriptional elongation at coding regions.Transcriptional regulation by Pho23 modulates the frequency of autophagosome formationHistone acetyltransferase Hbo1: catalytic activity, cellular abundance, and links to primary cancersThe MYST histone acetyltransferases are essential for gametophyte development in ArabidopsisGCN5 is a positive regulator of origins of DNA replication in Saccharomyces cerevisiae.Transcriptional Gene Silencing (TGS) via the RNAi Machinery in HIV-1 InfectionsHAT2 mediates histone H4K4 acetylation and affects micrococcal nuclease sensitivity of chromatin in Leishmania donovani.Identification of MYST3 as a novel epigenetic activator of ERα frequently amplified in breast cancer.Novel ZC3H7B-BCOR, MEAF6-PHF1, and EPC1-PHF1 fusions in ossifying fibromyxoid tumors--molecular characterization shows genetic overlap with endometrial stromal sarcoma.Small molecule inhibitors of histone acetyltransferase Tip60The ING gene family in the regulation of cell growth and tumorigenesis.Bypassing the requirement for an essential MYST acetyltransferase.Inhibitor of growth-4 promotes IkappaB promoter activation to suppress NF-kappaB signaling and innate immunityAn efficient high-throughput screening method for MYST family acetyltransferases, a new class of epigenetic drug targets.Histones: Controlling Tumor Signaling CircuitryPerspectives on the discovery of small-molecule modulators for epigenetic processes.Conserved molecular interactions within the HBO1 acetyltransferase complexes regulate cell proliferationNovel fusion of MYST/Esa1-associated factor 6 and PHF1 in endometrial stromal sarcoma.Exchange of associated factors directs a switch in HBO1 acetyltransferase histone tail specificity.The TIP60 Complex Regulates Bivalent Chromatin Recognition by 53BP1 through Direct H4K20me Binding and H2AK15 Acetylation.HBO1 HAT complexes target chromatin throughout gene coding regions via multiple PHD finger interactions with histone H3 tail.Energizing Genetics and Epi-genetics: Role in the Regulation of Mitochondrial Function.Histone modifiers in cancer: friends or foes?Structure and nucleosome interaction of the yeast NuA4 and Piccolo-NuA4 histone acetyltransferase complexes.T2DM: Why Epigenetics?Conserved herpesvirus kinases target the DNA damage response pathway and TIP60 histone acetyltransferase to promote virus replication.Successful strategies in the discovery of small-molecule epigenetic modulators with anticancer potential.Eaf1p Is Required for Recruitment of NuA4 in Targeting TFIID to the Promoters of the Ribosomal Protein Genes for Transcriptional Initiation In Vivo.The Set3 Complex Antagonizes the MYST Acetyltransferase Esa1 in the DNA Damage Response.
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The MYST family of histone acetyltransferases and their intimate links to cancer.
description
2007 nî lūn-bûn
@nan
2007年の論文
@ja
2007年論文
@yue
2007年論文
@zh-hant
2007年論文
@zh-hk
2007年論文
@zh-mo
2007年論文
@zh-tw
2007年论文
@wuu
2007年论文
@zh
2007年论文
@zh-cn
name
The MYST family of histone acetyltransferases and their intimate links to cancer.
@en
type
label
The MYST family of histone acetyltransferases and their intimate links to cancer.
@en
prefLabel
The MYST family of histone acetyltransferases and their intimate links to cancer.
@en
P2860
P356
P1433
P1476
The MYST family of histone acetyltransferases and their intimate links to cancer
@en
P2093
Avvakumov N
P2860
P2888
P304
P356
10.1038/SJ.ONC.1210608
P407
P50
P577
2007-08-01T00:00:00Z