Maintenance and propagation of a deleterious mitochondrial genome by the mitochondrial unfolded protein response.
about
Mitochondria Know No Boundaries: Mechanisms and Functions of Intercellular Mitochondrial TransferSending Out an SOS: Mitochondria as a Signaling HubmtDNA, Metastasis, and the Mitochondrial Unfolded Protein Response (UPRmt).Reducing the information gap on Loricarioidei (Siluriformes) mitochondrial genomics.Recent Insights into the Role of Unfolded Protein Response in ER Stress in Health and Disease.Chemosensory and hyperoxia circuits in C. elegans males influence sperm navigational capacity.Latent mitochondrial DNA deletion mutations drive muscle fiber loss at old age.Homeostatic Responses Regulate Selfish Mitochondrial Genome Dynamics in C. elegans.Mitochondrial fusion, fission, and mitochondrial toxicity.Inherited mitochondrial genomic instability and chemical exposures.Proteostasis and ageing: insights from long-lived mutant mice.Mitochondrial Mutations in Cardiac Disorders.Selected mitochondrial DNA landscapes activate the SIRT3 axis of the UPRmt to promote metastasisMitochondrial respiratory gene expression is suppressed in many cancers.Integrating the UPRmt into the mitochondrial maintenance network.Cellular and population level processes influence the rate, accumulation and observed frequency of inherited and somatic mtDNA mutations.The Transcription Factor ATF5 Mediates a Mammalian Mitochondrial UPRThe Mitochondrial Unfolded Protein Response as a Non-Oncogene Addiction to Support Adaptation to Stress during Transformation in Cancer and Beyond.Asymmetric Arginine Dimethylation Modulates Mitochondrial Energy Metabolism and Homeostasis in Caenorhabditis elegans.Autophagy impairment with lysosomal and mitochondrial dysfunction is an important characteristic of oxidative stress-induced senescence.Mitophagy in maintaining skeletal muscle mitochondrial proteostasis and metabolic health with ageing.Cell Biology of the Mitochondrion.The mitochondrial UPR: mechanisms, physiological functions and implications in ageing.A multimethod computational simulation approach for investigating mitochondrial dynamics and dysfunction in degenerative aging.Mitochondrial Stress Restores the Heat Shock Response and Prevents Proteostasis Collapse during Aging.Activation of the mitochondrial unfolded protein response promotes longevity and dopamine neuron survival in Parkinson's disease models.Preferential amplification of a human mitochondrial DNA deletion in vitro and in vivo.Dysregulation of the Mitochondrial Unfolded Protein Response Induces Non-Apoptotic Dopaminergic Neurodegeneration in C. elegans Models of Parkinson's Disease.Mitochondrial fission facilitates the selective mitophagy of protein aggregates.Sex specific activation of the ERα axis of the mitochondrial UPR (UPRmt) in the G93A-SOD1 mouse model of familial ALS.Pharmacoperones as Novel Therapeutics for Diverse Protein Conformational Diseases.UPRmt regulation and output: a stress response mediated by mitochondrial-nuclear communication.Mitochondrial genome variability: the effect on cellular functional activity.The mitochondrial unfolded protein response: Signaling from the powerhouse.Mitochondrial Retrograde Signaling in Mammals Is Mediated by the Transcriptional Cofactor GPS2 via Direct Mitochondria-to-Nucleus TranslocationThe mitochondrial unfolded protein response is activated upon hematopoietic stem cell exit from quiescence.Targeting Mitochondria to Counteract Age-Related Cellular Dysfunction.Long term rapamycin treatment improves mitochondrial DNA quality in aging mice.A Futile Battle? Protein Quality Control and the Stress of Aging.From discovery of the CHOP axis and targeting ClpP to the identification of additional axes of the UPRmt driven by the estrogen receptor and SIRT3.
P2860
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P2860
Maintenance and propagation of a deleterious mitochondrial genome by the mitochondrial unfolded protein response.
description
2016 nî lūn-bûn
@nan
2016年の論文
@ja
2016年論文
@yue
2016年論文
@zh-hant
2016年論文
@zh-hk
2016年論文
@zh-mo
2016年論文
@zh-tw
2016年论文
@wuu
2016年论文
@zh
2016年论文
@zh-cn
name
Maintenance and propagation of ...... ial unfolded protein response.
@en
type
label
Maintenance and propagation of ...... ial unfolded protein response.
@en
prefLabel
Maintenance and propagation of ...... ial unfolded protein response.
@en
P2093
P2860
P356
P1433
P1476
Maintenance and propagation of ...... ial unfolded protein response.
@en
P2093
Anna M Schulz
Cole M Haynes
Mark W Pellegrino
Shai Shaham
Yi-Fan Lin
P2860
P2888
P304
P356
10.1038/NATURE17989
P407
P577
2016-05-02T00:00:00Z
P6179
1037037687