The ligand-binding profile of HARE: hyaluronan and chondroitin sulfates A, C, and D bind to overlapping sites distinct from the sites for heparin, acetylated low-density lipoprotein, dermatan sulfate, and CS-E.
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Stabilin-2 modulates the efficiency of myoblast fusion during myogenic differentiation and muscle regeneration.In vivo siRNA delivery system for targeting to the liver by poly-l-glutamic acid-coated lipoplexHyaluronan polymer length, grafting density, and surface poly(ethylene glycol) coating influence in vivo circulation and tumor targeting of hyaluronan-grafted liposomes.Novel associations of multiple genetic loci with plasma levels of factor VII, factor VIII, and von Willebrand factor: The CHARGE (Cohorts for Heart and Aging Research in Genome Epidemiology) ConsortiumN-Glycans on the link domain of human HARE/Stabilin-2 are needed for hyaluronan binding to purified ecto-domain, but not for cellular endocytosis of hyaluronanA hyaluronan receptor for endocytosis (HARE) link domain N-glycan is required for extracellular signal-regulated kinase (ERK) and nuclear factor-κB (NF-κB) signaling in response to the uptake of hyaluronan but not heparin, dermatan sulfate, or acetyTissue-specific splice variants of HARE/Stabilin-2 are expressed in bone marrow, lymph node, and spleen.HARE-Mediated Endocytosis of Hyaluronan and Heparin Is Targeted by Different Subsets of Three Endocytic Motifs.Inhibition of Stabilin-2 elevates circulating hyaluronic acid levels and prevents tumor metastasisActivation of ERK and NF-κB during HARE-Mediated Heparin Uptake Require Only One of the Four Endocytic Motifs.Probing structural selectivity of synthetic heparin binding to Stabilin protein receptorsPerinatal changes in mitral and aortic valve structure and composition.Stabilin-1 and Stabilin-2 are specific receptors for the cellular internalization of phosphorothioate-modified antisense oligonucleotides (ASOs) in the liver.Rat and human HARE/stabilin-2 are clearance receptors for high- and low-molecular-weight heparins.Genome-wide association studies identify genetic loci for low von Willebrand factor levelsChemical synthesis of a hyaluronic acid decasaccharide.Antinociceptive activity of CC44, a biotinylated improgan congener.Hyaluronic acid receptor for endocytosis (HARE)-mediated endocytosis of hyaluronan, heparin, dermatan sulfate, and acetylated low density lipoprotein (AcLDL), but not chondroitin sulfate types A, C, D, or E, activates NF-κB-regulated gene expressionAntisense Oligonucleotides: Treatment Strategies and Cellular Internalization.The scavenger endothelial cell: a new player in homeostasis and immunity.The binding properties of minimal oligosaccharides reveal a common heparan sulfate/dermatan sulfate-binding site in hepatocyte growth factor/scatter factor that can accommodate a wide variety of sulfation patterns.Liver Sinusoidal Endothelial Cells.Chondroitin sulphate: a focus on osteoarthritis.Stabilin-2 mediates homophilic cell-cell interactions via its FAS1 domains.Systemic blockade of the hyaluronan receptor for endocytosis prevents lymph node metastasis of prostate cancer.Arabidopsis thaliana FLA4 functions as a glycan-stabilized soluble factor via its carboxy-proximal Fasciclin 1 domain.Hyaluronidase 1 and β-hexosaminidase have redundant functions in hyaluronan and chondroitin sulfate degradation.Directing Nanoparticle Biodistribution through Evasion and Exploitation of Stab2-Dependent Nanoparticle Uptake.Receptor-Mediated Uptake of Phosphorothioate Antisense Oligonucleotides in Different Cell Types of the Liver.STAB2 (FEEL-2) binds ligandsStructural Determinants for the Interactions of Chemically Modified Nucleic Acids with the Stabilin-2 Clearance Receptor.Single-Molecule Unbinding Forces between the Polysaccharide Hyaluronan and Its Binding Proteins
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P2860
The ligand-binding profile of HARE: hyaluronan and chondroitin sulfates A, C, and D bind to overlapping sites distinct from the sites for heparin, acetylated low-density lipoprotein, dermatan sulfate, and CS-E.
description
2008 nî lūn-bûn
@nan
2008年の論文
@ja
2008年論文
@yue
2008年論文
@zh-hant
2008年論文
@zh-hk
2008年論文
@zh-mo
2008年論文
@zh-tw
2008年论文
@wuu
2008年论文
@zh
2008年论文
@zh-cn
name
The ligand-binding profile of ...... n, dermatan sulfate, and CS-E.
@en
type
label
The ligand-binding profile of ...... n, dermatan sulfate, and CS-E.
@en
prefLabel
The ligand-binding profile of ...... n, dermatan sulfate, and CS-E.
@en
P2860
P356
P1433
P1476
The ligand-binding profile of ...... n, dermatan sulfate, and CS-E.
@en
P2093
Edward N Harris
Paul H Weigel
P2860
P304
P356
10.1093/GLYCOB/CWN045
P577
2008-05-22T00:00:00Z