HIV-1 Vpr protein directly loads helicase-like transcription factor (HLTF) onto the CRL4-DCAF1 E3 ubiquitin ligase.

about

HIV-1 Vpr hijacks EDD-DYRK2-DDB1DCAF1 to disrupt centrosome homeostasis.HIV-1 Vpr Reprograms CLR4 E3 Ubiquitin Ligase to Antagonize Exonuclease 1-Mediated Restriction of HIV-1 Infection

P2860

Q53820052-E09688AB-EABC-447F-A1BA-F0DE823DA3CD Q57798568-3E3A4519-D735-476D-8502-56C93CBB6818

P2860

HIV-1 Vpr protein directly loads helicase-like transcription factor (HLTF) onto the CRL4-DCAF1 E3 ubiquitin ligase.

Item

http://www.wikidata.org/entity/Q47592848

description

2017 nî lūn-bûn

@nan

2017年の論文

@ja

2017年学术文章

@wuu

2017年学术文章

@zh

2017年学术文章

@zh-cn

2017年学术文章

@zh-hans

2017年学术文章

@zh-my

2017年学术文章

@zh-sg

2017年學術文章

@yue

2017年學術文章

@zh-hant

name

HIV-1 Vpr protein directly loa ...... RL4-DCAF1 E3 ubiquitin ligase.

@en

HIV-1 Vpr protein directly loads helicase-like transcription factor

@nl

type

Item

label

HIV-1 Vpr protein directly loa ...... RL4-DCAF1 E3 ubiquitin ligase.

@en

HIV-1 Vpr protein directly loads helicase-like transcription factor

@nl

prefLabel

HIV-1 Vpr protein directly loa ...... RL4-DCAF1 E3 ubiquitin ligase.

@en

HIV-1 Vpr protein directly loads helicase-like transcription factor

@nl

P1476

HIV-1 Vpr protein directly loa ...... CRL4-DCAF1 E3 ubiquitin ligase

@en

P2093

Caili Hao

http://www.w3.org/2001/XMLSchema#string

Christina Monnie

http://www.w3.org/2001/XMLSchema#string

Jacek Skowronski

http://www.w3.org/2001/XMLSchema#string

Jinwoo Ahn

http://www.w3.org/2001/XMLSchema#string

Kasia Hrecka

http://www.w3.org/2001/XMLSchema#string

Maria DeLucia

http://www.w3.org/2001/XMLSchema#string

P2860

HIV1 Vpr arrests the cell cycle by recruiting DCAF1/VprBP, a receptor of the Cul4-DDB1 ubiquitin ligase

Premature activation of the SLX4 complex by Vpr promotes G2/M arrest and escape from innate immune sensing

Polyubiquitination of proliferating cell nuclear antigen by HLTF and SHPRH prevents genomic instability from stalled replication forks

Human HLTF functions as a ubiquitin ligase for proliferating cell nuclear antigen polyubiquitination

DDB1 and Cul4A are required for human immunodeficiency virus type 1 Vpr-induced G2 arrest

Human immunodeficiency virus type 1 vpr gene induces phenotypic effects similar to those of the DNA alkylating agent, nitrogen mustard

Lentiviral Vpr usurps Cul4-DDB1[VprBP] E3 ubiquitin ligase to modulate cell cycle

Formation of mobile chromatin-associated nuclear foci containing HIV-1 Vpr and VPRBP is critical for the induction of G2 cell cycle arrest

The DDB1-DCAF1-Vpr-UNG2 crystal structure reveals how HIV-1 Vpr steers human UNG2 toward destruction

Mechanisms underlying ubiquitination

P304

21117-21127

http://www.w3.org/2001/XMLSchema#string

P31

scholarly article

P356

10.1074/JBC.M117.798801

http://www.w3.org/2001/XMLSchema#string

P407

English

P433

http://www.w3.org/2001/XMLSchema#string

P478

292

http://www.w3.org/2001/XMLSchema#string

P50

Xiaohong Zhou

P577

2017-10-27T00:00:00Z

http://www.w3.org/2001/XMLSchema#dateTime

P698

29079575

http://www.w3.org/2001/XMLSchema#string

P932

5743084

http://www.w3.org/2001/XMLSchema#string

HIV-1 Vpr protein directly loads helicase-like transcription factor (HLTF) onto the CRL4-DCAF1 E3 ubiquitin ligase.

about

P2860

P2860

HIV-1 Vpr protein directly loads helicase-like transcription factor (HLTF) onto the CRL4-DCAF1 E3 ubiquitin ligase.

description

name

type

label

prefLabel

P1433

P1476

P2093

P2860

P304

P31

P356

P407

P433

P478

P50

P577

P698

P932

P356

P1433

P1476

P2093

P2860

P304

P31

P356

P407

P433

P478

P50

P577

P698

P932