Mouse APOBEC3 restricts friend leukemia virus infection and pathogenesis in vivo
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The mouse "xenotropic" gammaretroviruses and their XPR1 receptorHow Active Are Porcine Endogenous Retroviruses (PERVs)?Infection of adult thymus with murine retrovirus induces virus-specific central tolerance that prevents functional memory CD8+ T cell differentiationIntrinsic immunity against retrotransposons by APOBEC cytidine deaminasesStudies on the restriction of murine leukemia viruses by mouse APOBEC3Tetherin/BST-2: Restriction Factor or Immunomodulator?Noninfectious retrovirus particles drive the APOBEC3/Rfv3 dependent neutralizing antibody responseAre viruses inhibited by APOBEC3 molecules from their host species?Type I interferon signaling is required for the APOBEC3/Rfv3-dependent neutralizing antibody response but not innate retrovirus restriction.Adaptive evolution of Mus Apobec3 includes retroviral insertion and positive selection at two clusters of residues flanking the substrate groove.Apobec 3G efficiently reduces infectivity of the human exogenous gammaretrovirus XMRVActivation of the N-terminally truncated form of the Stk receptor tyrosine kinase Sf-Stk by Friend virus-encoded gp55 is mediated by cysteine residues in the ecotropic domain of gp55 and the extracellular domain of Sf-Stk.Different modes of retrovirus restriction by human APOBEC3A and APOBEC3G in vivo.Host restriction of murine gammaherpesvirus 68 replication by human APOBEC3 cytidine deaminases but not murine APOBEC3.Immunoglobulin somatic hypermutation by APOBEC3/Rfv3 during retroviral infectionSusceptibility of xenotropic murine leukemia virus-related virus (XMRV) to retroviral restriction factors.Incorporation of mouse APOBEC3 into murine leukemia virus virions decreases the activity and fidelity of reverse transcriptase.Two genetic determinants acquired late in Mus evolution regulate the inclusion of exon 5, which alters mouse APOBEC3 translation efficiencyMouse mammary tumor virus molecular biology and oncogenesisMouse knockout models for HIV-1 restriction factors.The glycosylated Gag protein of a murine leukemia virus inhibits the antiretroviral function of APOBEC3.Tetherin promotes the innate and adaptive cell-mediated immune response against retrovirus infection in vivo.A single nucleotide polymorphism in tetherin promotes retrovirus restriction in vivo.Persistent Friend virus replication and disease in Apobec3-deficient mice expressing functional B-cell-activating factor receptor.APOBEC3 proteins expressed in mammary epithelial cells are packaged into retroviruses and can restrict transmission of milk-borne virionsInnate retroviral restriction by Apobec3 promotes antibody affinity maturation in vivo.Antiretroviral restriction factors in mice.Fv1 restriction and retrovirus vaccine immunity in Apobec3-deficient 129P2 mice.APOBEC3-mediated hypermutation of retroviral vectors produced from some retrovirus packaging cell linesOrigins of the endogenous and infectious laboratory mouse gammaretroviruses.Genetic analysis of the localization of APOBEC3F to human immunodeficiency virus type 1 virion cores.Increased APOBEC3G and APOBEC3F expression is associated with low viral load and prolonged survival in simian immunodeficiency virus infected rhesus monkeys.Reassessment of murine APOBEC1 as a retrovirus restriction factor in vivo.Phylogeny-directed search for murine leukemia virus-like retroviruses in vertebrate genomes and in patients suffering from myalgic encephalomyelitis/chronic fatigue syndrome and prostate cancerBrain tumor eradication and prolonged survival from intratumoral conversion of 5-fluorocytosine to 5-fluorouracil using a nonlytic retroviral replicating vectorInfection barriers to successful xenotransplantation focusing on porcine endogenous retroviruses.APOBEC3 versus Retroviruses, Immunity versus Invasion: Clash of the Titans.Antiviral Mechanism and Biochemical Basis of the Human APOBEC3 Family.A novel role for APOBEC3: susceptibility to sexual transmission of murine acquired immunodeficiency virus (mAIDS) is aggravated in APOBEC3 deficient mice.Retroelements versus APOBEC3 family members: No great escape from the magnificent seven
P2860
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P2860
Mouse APOBEC3 restricts friend leukemia virus infection and pathogenesis in vivo
description
2008 nî lūn-bûn
@nan
2008年の論文
@ja
2008年論文
@yue
2008年論文
@zh-hant
2008年論文
@zh-hk
2008年論文
@zh-mo
2008年論文
@zh-tw
2008年论文
@wuu
2008年论文
@zh
2008年论文
@zh-cn
name
Mouse APOBEC3 restricts friend leukemia virus infection and pathogenesis in vivo
@en
type
label
Mouse APOBEC3 restricts friend leukemia virus infection and pathogenesis in vivo
@en
prefLabel
Mouse APOBEC3 restricts friend leukemia virus infection and pathogenesis in vivo
@en
P2093
P2860
P356
P1433
P1476
Mouse APOBEC3 restricts friend leukemia virus infection and pathogenesis in vivo
@en
P2093
Cristina Rada
Eri Takeda
Marc-André Langlois
Masaaki Miyazawa
Mayumi Sakamoto
Michael S Neuberger
Sachiyo Tsuji-Kawahara
P2860
P304
10998-11008
P356
10.1128/JVI.01311-08
P407
P577
2008-09-10T00:00:00Z