PTTG: an important target gene for ovarian cancer therapy.
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PTTG1 inhibits SMAD3 in prostate cancer cells to promote their proliferationNetwork Based Prediction Model for Genomics Data Analysis.Effect of PTTG on endogenous gene expression in HEK 293 cells.Cdc20 and securin overexpression predict short-term breast cancer survival.A systematic approach to identify novel cancer drug targets using machine learning, inhibitor design and high-throughput screening.Autophagy promotes radiation-induced senescence but inhibits bystander effects in human breast cancer cells.Tumorigenic potential of pituitary tumor transforming gene (PTTG) in vivo investigated using a transgenic mouse model, and effects of cross breeding with p53 (+/-) transgenic mice.Pituitary tumor transforming gene induces epithelial to mesenchymal transition by regulation of Twist, Snail, Slug, and E-cadherin.PTTG1 oncogene promotes tumor malignancy via epithelial to mesenchymal transition and expansion of cancer stem cell populationPTTG regulates the metabolic switch of ovarian cancer cells via the c-myc pathway.Identification of potential therapeutic targets for lung cancer by bioinformatics analysisRadiation-induced senescence in securin-deficient cancer cells promotes cell invasion involving the IL-6/STAT3 and PDGF-BB/PDGFR pathwaysPTTG acts as a STAT3 target gene for colorectal cancer cell growth and motility.Pituitary tumor-transforming gene-1 serves as an independent prognostic biomarker for gastric cancer.Pttg1 inhibits TGFβ signaling in breast cancer cells to promote their growth.Pituitary tumor-transforming gene 1 (PTTG1) is overexpressed in oral squamous cell carcinoma (OSCC) and promotes migration, invasion and epithelial-mesenchymal transition (EMT) in SCC15 cells.Gene expression profiles in human HepG2 cells treated with extracts of the Tamarindus indica fruit pulp.MiRNA-494 inhibits metastasis of cervical cancer through Pttg1.PTTG1 cooperated with GLI1 leads to epithelial-mesenchymal transition in esophageal squamous cell cancer.MicroRNA-520d-5p inhibits human glioma cell proliferation and induces cell cycle arrest by directly targeting PTTG1.Targeting the PTTG1 oncogene impairs proliferation and invasiveness of melanoma cells sensitive or with acquired resistance to the BRAF inhibitor dabrafenib.Dysregulation of AKT3 along with a small panel of mRNAs stratifies high-grade serous ovarian cancer from both normal epithelia and benign tumor tissues.Altered expression of securin (Pttg1) and serpina3n in the auditory system of hearing-impaired Tff3-deficient mice.Prognostic implications of securin expression and sub-cellular localization in human breast cancer.
P2860
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P2860
PTTG: an important target gene for ovarian cancer therapy.
description
2008 nî lūn-bûn
@nan
2008年の論文
@ja
2008年論文
@yue
2008年論文
@zh-hant
2008年論文
@zh-hk
2008年論文
@zh-mo
2008年論文
@zh-tw
2008年论文
@wuu
2008年论文
@zh
2008年论文
@zh-cn
name
PTTG: an important target gene for ovarian cancer therapy.
@en
type
label
PTTG: an important target gene for ovarian cancer therapy.
@en
prefLabel
PTTG: an important target gene for ovarian cancer therapy.
@en
P2093
P2860
P356
P1476
PTTG: an important target gene for ovarian cancer therapy.
@en
P2093
Casey Yeakel
Sham S Kakar
Siva Kumar Panguluri
P2860
P2888
P356
10.1186/1757-2215-1-6
P577
2008-10-20T00:00:00Z
P5875
P6179
1003214086