Human securin, hPTTG, is associated with Ku heterodimer, the regulatory subunit of the DNA-dependent protein kinase - Test2 - elhamkhani - TriplyDB

Human securin, hPTTG, is associated with Ku heterodimer, the regulatory subunit of the DNA-dependent protein kinase

Human securin, hPTTG, is associated with Ku heterodimer, the regulatory subunit of the DNA-dependent protein kinase

http://www.wikidata.org/entity/Q24612772

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PTTG/securin activates expression of p53 and modulates its function Human securin interacts with p53 and modulates p53-mediated transcriptional activity and apoptosis Securin enhances the anti-cancer effects of 6-methoxy-3-(3',4',5'-trimethoxy-benzoyl)-1H-indole (BPR0L075) in human colorectal cancer cells Critical differences between isoforms of securin reveal mechanisms of separase regulation Methylation alterations are not a major cause of PTTG1 misregulation.Pituitary tumor transforming gene-1 haplotypes and risk of pituitary adenoma: a case-control study.Overexpression of the pituitary tumor transforming gene induces p53-dependent senescence through activating DNA damage response pathway in normal human fibroblasts.Secured cutting: controlling separase at the metaphase to anaphase transition Down-regulation of the oncogene PTTG1 via the KLF6 tumor suppressor during induction of myeloid differentiation.Targeting zebrafish and murine pituitary corticotroph tumors with a cyclin-dependent kinase (CDK) inhibitor Glycogen synthase kinase-3beta (GSK3beta) negatively regulates PTTG1/human securin protein stability, and GSK3beta inactivation correlates with securin accumulation in breast tumors.Overexpressed hPTTG1 promotes breast cancer cell invasion and metastasis by regulating GEF-H1/RhoA signalling Meta-analysis reveals conserved cell cycle transcriptional network across multiple human cell types.Proliferation marker securin identifies favourable outcome in invasive ductal breast cancer.PTTG promotes invasion in human breast cancer cell line by upregulating EMMPRIN via FAK/Akt/mTOR signaling p21(Cip1) restrains pituitary tumor growth.PTTG: an important target gene for ovarian cancer therapy.Securin is a target of the UV response pathway in mammalian cells Cdh1 regulates cell cycle through modulating the claspin/Chk1 and the Rb/E2F1 pathways.E2F1 induces pituitary tumor transforming gene (PTTG1) expression in human pituitary tumors PTTG acts as a STAT3 target gene for colorectal cancer cell growth and motility.Key signaling molecules in pituitary tumors.Mechanisms of therapeutic resistance in cancer (stem) cells with emphasis on thyroid cancer cells.Cohesin: a regulator of genome integrity and gene expression.Labeling index in pituitary adenomas evaluated by means of MIB-1: is there a prognostic role? A critical review.Pituitary tumor-transforming gene and its binding factor in endocrine cancer.The proto-oncogene PBF binds p53 and is associated with prognostic features in colorectal cancer.Proliferative potential after DNA damage and non-homologous end joining are affected by loss of securin.Pituitary tumour transforming gene (PTTG) induces genetic instability in thyroid cells.Pituitary tumor transforming gene: a novel therapeutic target for glioma treatment.Protein phosphatase 2A stabilizes human securin, whose phosphorylated forms are degraded via the SCF ubiquitin ligase.Induction of Dlk1 by PTTG1 inhibits adipocyte differentiation and correlates with malignant transformation.Oct-1 induces pituitary tumor transforming gene expression in endocrine tumors Securin a new role for itself.Human full-length Securin is a natively unfolded protein.DNA damage-induced inhibition of securin expression is mediated by p53.MicroRNA-520d-5p inhibits human glioma cell proliferation and induces cell cycle arrest by directly targeting PTTG1.Altered expression of securin (Pttg1) and serpina3n in the auditory system of hearing-impaired Tff3-deficient mice.Response of Myeloid Leukemia Cells to Luteolin is Modulated by Differentially Expressed Pituitary Tumor-Transforming Gene 1 (PTTG1) Oncoprotein.Changes in PTTG1 by human TERT gene expression modulate the self-renewal of placenta-derived mesenchymal stem cells.

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Human securin, hPTTG, is associated with Ku heterodimer, the regulatory subunit of the DNA-dependent protein kinase

http://www.wikidata.org/entity/Q24612772

description

2001 nî lūn-bûn

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2001年學術文章

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name

Human securin, hPTTG, is assoc ...... e DNA-dependent protein kinase

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Human securin, hPTTG, is assoc ...... e DNA-dependent protein kinase

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Human securin, hPTTG, is assoc ...... e DNA-dependent protein kinase

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Human securin, hPTTG, is assoc ...... e DNA-dependent protein kinase

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Human securin, hPTTG, is assoc ...... e DNA-dependent protein kinase

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Human securin, hPTTG, is assoc ...... e DNA-dependent protein kinase

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A Domínguez

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F Ramos-Morales

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P2860

hpttg, a human homologue of rat pttg, is overexpressed in hematopoietic neoplasms. Evidence for a transcriptional activation function of hPTTG

DNA sequencing with chain-terminating inhibitors

Human Sos1: a guanine nucleotide exchange factor for Ras that binds to GRB2

Components of the Ku-dependent non-homologous end-joining pathway are involved in telomeric length maintenance and telomeric silencing.

Yeast cohesin complex requires a conserved protein, Eco1p(Ctf7), to establish cohesion between sister chromatids during DNA replication

p95vav associates with the nuclear protein Ku-70

GMAP-210, A cis-Golgi network-associated protein, is a minus end microtubule-binding protein

A novel genetic system to detect protein-protein interactions

The two-hybrid system: a method to identify and clone genes for proteins that interact with a protein of interest

Genetic instabilities in human cancers

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