Cinnamoyl-based Nrf2-activators targeting human skin cell photo-oxidative stress
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The topical antimicrobial zinc pyrithione is a heat shock response inducer that causes DNA damage and PARP-dependent energy crisis in human skin cellsRedox-directed cancer therapeutics: molecular mechanisms and opportunitiesThe cinnamon-derived Michael acceptor cinnamic aldehyde impairs melanoma cell proliferation, invasiveness, and tumor growthEffect of redox modulating NRF2 activators on chronic kidney diseaseA perspective on dietary phytochemicals and cancer chemoprevention: oxidative stress, nrf2, and epigenomicsTrxR1 as a potent regulator of the Nrf2-Keap1 response systemStress-activated cap'n'collar transcription factors in aging and human diseaseThe Nrf2-inducers tanshinone I and dihydrotanshinone protect human skin cells and reconstructed human skin against solar simulated UVPlant extracts of the family Lauraceae: a potential resource for chemopreventive agents that activate the nuclear factor-erythroid 2-related factor 2/antioxidant response element pathwaySystemic administration of the apocarotenoid bixin protects skin against solar UV-induced damage through activation of NRF2Discovery of potent, novel Nrf2 inducers via quantum modeling, virtual screening, and in vitro experimental validation.Nrf2 null enhances UVB-induced skin inflammation and extracellular matrix damages.Chemistry of the cysteine sensors in Kelch-like ECH-associated protein 1The malondialdehyde-derived fluorophore DHP-lysine is a potent sensitizer of UVA-induced photooxidative stress in human skin cells.The cinnamon-derived dietary factor cinnamic aldehyde activates the Nrf2-dependent antioxidant response in human epithelial colon cells.Estrogen receptor and PI3K/Akt signaling pathway involvement in S-(-)equol-induced activation of Nrf2/ARE in endothelial cellsTherapeutic potential of Nrf2 activators in streptozotocin-induced diabetic nephropathy.Nrf2-dependent suppression of azoxymethane/dextran sulfate sodium-induced colon carcinogenesis by the cinnamon-derived dietary factor cinnamaldehyde.The Tryptophan-Derived Endogenous Aryl Hydrocarbon Receptor Ligand 6-Formylindolo[3,2-b]Carbazole Is a Nanomolar UVA Photosensitizer in Epidermal Keratinocytes.Glutathione homeostasis and functions: potential targets for medical interventionsSINGLET OXYGEN RESISTANT 1 links reactive electrophile signaling to singlet oxygen acclimation in Chlamydomonas reinhardtii.Diabetic Wound Healing and Activation of Nrf2 by Herbal MedicineNew hits as phase II enzymes inducers from a focused library with heteroatom-heteroatom and Michael-acceptor motives.Photoprotection by dietary phenolics against melanogenesis induced by UVA through Nrf2-dependent antioxidant responses.An Essential Role of NRF2 in Diabetic Wound Healing.The experimental chemotherapeutic N6-furfuryladenosine (kinetin-riboside) induces rapid ATP depletion, genotoxic stress, and CDKN1A(p21) upregulation in human cancer cell linesActivation of Nrf2 Reduces UVA-Mediated MMP-1 Upregulation via MAPK/AP-1 Signaling Cascades: The Photoprotective Effects of Sulforaphane and HispidulinAn evidence-based systematic review of cinnamon (Cinnamomum spp.) by the Natural Standard Research Collaboration.Natural product-derived pharmacological modulators of Nrf2/ARE pathway for chronic diseases.The glutathione system: a new drug target in neuroimmune disorders.Prevention of Photocarcinogenesis by Agonists of 5-HT1A and Antagonists of 5-HT2A Receptors.3-(2-oxoethylidene)indolin-2-one derivatives activate Nrf2 and inhibit NF-κB: potential candidates for chemoprevention.Searching phase II enzymes inducers, from Michael acceptor-[1,2]dithiolethione hybrids, as cancer chemopreventive agents.Nrf2: a potential therapeutic target for diabetic neuropathy.A new in vitro method for identifying chemical sensitizers combining peptide binding with ARE/EpRE-mediated gene expression in human skin cells.Impact of Nrf2 on UVB-induced skin inflammation/photoprotection and photoprotective effect of sulforaphane.An inelastic neutron scattering study of dietary phenolic acids.Targeting NRF2 for Improved Skin Barrier Function and Photoprotection: Focus on the Achiote-Derived Apocarotenoid Bixin.Topical Bixin Confers NRF2-Dependent Protection Against Photodamage and Hair Graying in Mouse Skin.The B6 -vitamer Pyridoxal is a Sensitizer of UVA-induced Genotoxic Stress in Human Primary Keratinocytes and Reconstructed Epidermis.
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P2860
Cinnamoyl-based Nrf2-activators targeting human skin cell photo-oxidative stress
description
article científic
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article scientifique
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articolo scientifico
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artigo científico
@pt
bilimsel makale
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scientific article published on 26 April 2008
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
Cinnamoyl-based Nrf2-activators targeting human skin cell photo-oxidative stress
@en
Cinnamoyl-based Nrf2-activators targeting human skin cell photo-oxidative stress.
@nl
type
label
Cinnamoyl-based Nrf2-activators targeting human skin cell photo-oxidative stress
@en
Cinnamoyl-based Nrf2-activators targeting human skin cell photo-oxidative stress.
@nl
prefLabel
Cinnamoyl-based Nrf2-activators targeting human skin cell photo-oxidative stress
@en
Cinnamoyl-based Nrf2-activators targeting human skin cell photo-oxidative stress.
@nl
P2093
P2860
P1476
Cinnamoyl-based Nrf2-activators targeting human skin cell photo-oxidative stress
@en
P2093
Christopher M Cabello
Donna D Zhang
Georg T Wondrak
Nicole F Villeneuve
Shirley Zhang
Stephanie Ley
P2860
P304
P356
10.1016/J.FREERADBIOMED.2008.04.023
P577
2008-04-26T00:00:00Z