Novel bimodular DNA aptamers with guanosine quadruplexes inhibit phylogenetically diverse HIV-1 reverse transcriptases.
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G-Quadruplex Forming Oligonucleotides as Anti-HIV AgentsUse of Aptamers as Diagnostics Tools and Antiviral Agents for Human VirusesCharacterization of enhanced monovalent and bivalent thrombin DNA aptamer binding using single molecule force spectroscopy.RNA-protein interactions govern antiviral specificity and encapsidation of broad spectrum anti-HIV reverse transcriptase aptamersViral reverse transcriptases show selective high affinity binding to DNA-DNA primer-templates that resemble the polypurine tract.Detection of cyclic diguanylate G-octaplex assembly and interaction with proteinsDNA duplexes with hydrophobic modifications inhibit fusion between HIV-1 and cell membranes.Selection and Characterization of DNA Aptamers Targeting All Four Serotypes of Dengue VirusesDNA aptamers to human immunodeficiency virus reverse transcriptase selected by a primer-free SELEX method: characterization and comparison with other aptamers.Selection of 2'-deoxy-2'-fluoroarabinonucleotide (FANA) aptamers that bind HIV-1 reverse transcriptase with picomolar affinityHigh-throughput sequence analysis reveals structural diversity and improved potency among RNA inhibitors of HIV reverse transcriptase.Potent Inhibition of HIV-1 Reverse Transcriptase and Replication by Nonpseudoknot, "UCAA-motif" RNA Aptamers.G-quadruplex-interacting compounds alter latent DNA replication and episomal persistence of KSHV.The application of DNA and RNA G-quadruplexes to therapeutic medicines.Aptamers: multifunctional molecules for biomedical research.The G-quadruplex-forming aptamer AS1411 potently inhibits HIV-1 attachment to the host cell.Salt bridge exchange binding mechanism between streptavidin and its DNA aptamer--thermodynamics and spectroscopic evidences.Broad-spectrum aptamer inhibitors of HIV reverse transcriptase closely mimic natural substrates.Bi-specific aptamers mediating tumor cell lysis.Aptamers against pathogenic microorganisms.HIV-1 integrase inhibitor T30177 forms a stacked dimeric G-quadruplex structure containing bulges.Formation of a G-quadruplex at the BCL2 major breakpoint region of the t(14;18) translocation in follicular lymphoma.Aptamers in HIV research diagnosis and therapy.Thioflavin T as a fluorescence light-up probe for both parallel and antiparallel G-quadruplexes of 29-mer thrombin binding aptamer.
P2860
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P2860
Novel bimodular DNA aptamers with guanosine quadruplexes inhibit phylogenetically diverse HIV-1 reverse transcriptases.
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2008年の論文
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2008年学术文章
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2008年学术文章
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2008年学术文章
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name
Novel bimodular DNA aptamers w ...... HIV-1 reverse transcriptases.
@en
Novel bimodular DNA aptamers w ...... HIV-1 reverse transcriptases.
@nl
type
label
Novel bimodular DNA aptamers w ...... HIV-1 reverse transcriptases.
@en
Novel bimodular DNA aptamers w ...... HIV-1 reverse transcriptases.
@nl
prefLabel
Novel bimodular DNA aptamers w ...... HIV-1 reverse transcriptases.
@en
Novel bimodular DNA aptamers w ...... HIV-1 reverse transcriptases.
@nl
P2093
P2860
P356
P1476
Novel bimodular DNA aptamers w ...... HIV-1 reverse transcriptases.
@en
P2093
Daniel M Held
Daniel Michalowski
Donald H Burke
Rebecca Chitima-Matsiga
P2860
P304
P356
10.1093/NAR/GKN891
P407
P577
2008-11-07T00:00:00Z