High Systemic Exposure of Pyrazinoic Acid Has Limited Antituberculosis Activity in Murine and Rabbit Models of Tuberculosis.
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In Vivo-Selected Pyrazinoic Acid-Resistant Mycobacterium tuberculosis Strains Harbor Missense Mutations in the Aspartate Decarboxylase PanD and the Unfoldase ClpC1.Long-Chain Fatty Acyl Coenzyme A Ligase FadD2 Mediates Intrinsic Pyrazinamide Resistance in Mycobacterium tuberculosis.Missense Mutations in the Unfoldase ClpC1 of the Caseinolytic Protease Complex Are Associated with Pyrazinamide Resistance in Mycobacterium tuberculosisPharmacokinetics and pharmacogenetics of anti-tubercular drugs: a tool for treatment optimization?Coadministration of Allopurinol To Increase Antimycobacterial Efficacy of Pyrazinamide as Evaluated in a Whole-Blood Bactericidal Activity Model.Pyrazinamide Resistance Is Caused by Two Distinct Mechanisms: Prevention of Coenzyme A Depletion and Loss of Virulence Factor Synthesis.Impact of immunopathology on the antituberculous activity of pyrazinamide
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High Systemic Exposure of Pyrazinoic Acid Has Limited Antituberculosis Activity in Murine and Rabbit Models of Tuberculosis.
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article científic
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article scientifique
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articolo scientifico
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artigo científico
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bilimsel makale
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scientific article published on 02 May 2016
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
High Systemic Exposure of Pyra ...... Rabbit Models of Tuberculosis.
@en
High Systemic Exposure of Pyra ...... Rabbit Models of Tuberculosis.
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type
label
High Systemic Exposure of Pyra ...... Rabbit Models of Tuberculosis.
@en
High Systemic Exposure of Pyra ...... Rabbit Models of Tuberculosis.
@nl
prefLabel
High Systemic Exposure of Pyra ...... Rabbit Models of Tuberculosis.
@en
High Systemic Exposure of Pyra ...... Rabbit Models of Tuberculosis.
@nl
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P1476
High Systemic Exposure of Pyra ...... Rabbit Models of Tuberculosis.
@en
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David Alland
Eric Nuermberger
Hassan Safi
Jansy Sarathy
Michael Pinn
Paul O'Brien
Rokeya Tasneen
Véronique Dartois
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P304
P356
10.1128/AAC.03085-15
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P577
2016-05-02T00:00:00Z