Transcriptional response of the murine mammary gland to acute progesterone exposure
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Progestin effects on cell proliferation pathways in the postmenopausal mammary glandAmphiregulin mediates progesterone-induced mammary ductal development during pubertyMammary gland developmentEpithelial-Mesenchymal Transition (EMT) and Regulation of EMT Factors by Steroid Nuclear Receptors in Breast Cancer: A Review and in Silico InvestigationE Proteins and ID Proteins: Helix-Loop-Helix Partners in Development and DiseasePerturbing the cellular levels of steroid receptor coactivator-2 impairs murine endometrial function.Wnt4 is not sufficient to induce lobuloalveolar mammary development.Minireview: Progesterone Regulation of Proliferation in the Normal Human Breast and in Breast Cancer: A Tale of Two Scenarios?The antiproliferative effects of progestins in T47D breast cancer cells are tempered by progestin induction of the ETS transcription factor Elf5.MPA-induced gene expression and stromal and parenchymal gene expression profiles in luminal murine mammary carcinomas with different hormonal requirements.Two distinct mechanisms underlie progesterone-induced proliferation in the mammary gland.A murine uterine transcriptome, responsive to steroid receptor coactivator-2, reveals transcription factor 23 as essential for decidualization of human endometrial stromal cells.Subfertility linked to combined luteal insufficiency and uterine progesterone resistance.Progesterone receptors, their isoforms and progesterone regulated transcriptionTargeting RANKL to a specific subset of murine mammary epithelial cells induces ordered branching morphogenesis and alveologenesis in the absence of progesterone receptor expression.Progesterone action in endometrial cancer, endometriosis, uterine fibroids, and breast cancer.Tetratricopeptide repeat domain 9A negatively regulates estrogen receptor alpha activityAltered AIB1 or AIB1Δ3 expression impacts ERα effects on mammary gland stromal and epithelial contentA local basis for progesterone action during mammary tumorigenesis - no longer RANK and fileID4 regulates mammary gland development by suppressing p38MAPK activityFrom the ranks of mammary progesterone mediators, RANKL takes the spotlightThe biology of progesterone receptor in the normal mammary gland and in breast cancerProgesterone receptor directly inhibits β-casein gene transcription in mammary epithelial cells through promoting promoter and enhancer repressive chromatin modifications.Progestin regulated miRNAs that mediate progesterone receptor action in breast cancer.Research resource: progesterone receptor targetome underlying mammary gland branching morphogenesisFinally! A model for progesterone receptor action in normal human breastProgesterone receptor and Stat5 signaling cross talk through RANKL in mammary epithelial cells.RANKL inhibition: a promising novel strategy for breast cancer treatment.Endocrine hormones and local signals during the development of the mouse mammary gland.Steroid hormone receptors silence genes by a chromatin-targeted mechanism similar to those used for gene activation.Making milk: A new link between STAT5 and Akt1Effects of dietary apigenin on tumor latency, incidence and multiplicity in a medroxyprogesterone acetate-accelerated 7,12-dimethylbenz(a)anthracene-induced breast cancer model.Progesterone/RANKL is a major regulatory axis in the human breast.A mouse transgenic approach to induce β-catenin signaling in a temporally controlled manner.
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Transcriptional response of the murine mammary gland to acute progesterone exposure
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article científic
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article scientifique
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articolo scientifico
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artigo científico
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bilimsel makale
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scientific article published on 07 August 2008
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
Transcriptional response of the murine mammary gland to acute progesterone exposure
@en
Transcriptional response of the murine mammary gland to acute progesterone exposure.
@nl
type
label
Transcriptional response of the murine mammary gland to acute progesterone exposure
@en
Transcriptional response of the murine mammary gland to acute progesterone exposure.
@nl
prefLabel
Transcriptional response of the murine mammary gland to acute progesterone exposure
@en
Transcriptional response of the murine mammary gland to acute progesterone exposure.
@nl
P2093
P2860
P356
P1433
P1476
Transcriptional response of the murine mammary gland to acute progesterone exposure
@en
P2093
Adam C Buser
Atish Mukherjee
Chad J Creighton
Dean P Edwards
John P Lydon
Rodrigo Fernandez-Valdivia
P2860
P304
P356
10.1210/EN.2008-0768
P407
P577
2008-08-07T00:00:00Z