Phase I study of UCN-01 and perifosine in patients with relapsed and refractory acute leukemias and high-risk myelodysplastic syndrome.
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Trial Watch: Targeting ATM-CHK2 and ATR-CHK1 pathways for anticancer therapyTargeting the Mitotic Catastrophe Signaling Pathway in CancerMaximising the potential of AKT inhibitors as anti-cancer treatmentsDevelopment of synthetic lethality anticancer therapeutics.Selective anti-cancer agents as anti-aging drugsNew strategies in acute myelogenous leukemia: leukemogenesis and personalized medicine.Targeting phosphatidylinositol-3-kinase pathway for the treatment of Philadelphia-negative myeloproliferative neoplasms.Targeting mTOR signaling pathways and related negative feedback loops for the treatment of acute myeloid leukemia.Current clinical regulation of PI3K/PTEN/Akt/mTOR signalling in treatment of human cancer.Outlook on PI3K/AKT/mTOR inhibition in acute leukemia.Targeting Programmed Cell Death Using Small-Molecule Compounds to Improve Potential Cancer Therapy.Investigation of the Lipid Binding Properties of the Marburg Virus Matrix Protein VP40.Triple Akt inhibition as a new therapeutic strategy in T-cell acute lymphoblastic leukemia.Perifosine enhances bevacizumab-induced apoptosis and therapeutic efficacy by targeting PI3K/AKT pathway in a glioblastoma heterotopic model.STK3 is a therapeutic target for a subset of acute myeloid leukemias.
P2860
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P2860
Phase I study of UCN-01 and perifosine in patients with relapsed and refractory acute leukemias and high-risk myelodysplastic syndrome.
description
article científic
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article scientifique
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articolo scientifico
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artigo científico
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bilimsel makale
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scientific article published on 27 February 2013
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
Phase I study of UCN-01 and pe ...... risk myelodysplastic syndrome.
@en
Phase I study of UCN-01 and pe ...... risk myelodysplastic syndrome.
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type
label
Phase I study of UCN-01 and pe ...... risk myelodysplastic syndrome.
@en
Phase I study of UCN-01 and pe ...... risk myelodysplastic syndrome.
@nl
prefLabel
Phase I study of UCN-01 and pe ...... risk myelodysplastic syndrome.
@en
Phase I study of UCN-01 and pe ...... risk myelodysplastic syndrome.
@nl
P2093
P2860
P1476
Phase I study of UCN-01 and pe ...... risk myelodysplastic syndrome.
@en
P2093
Alexander Perl
Edward A Sausville
Ivana Gojo
Kelly J Norsworthy
Kenneth S Bauer
Maria R Baer
Martin Carroll
Michael Tidwell
Selina Luger
Stephanie Fleckinger
P2860
P2888
P304
P356
10.1007/S10637-013-9937-8
P577
2013-02-27T00:00:00Z