about
Activation of Akt signaling reduces the prevalence and intensity of malaria parasite infection and lifespan in Anopheles stephensi mosquitoesCritical role of PI3K/Akt/GSK3β in motoneuron specification from human neural stem cells in response to FGF2 and EGFMolecular basis of signaling specificity of insulin and IGF receptors: neglected corners and recent advancesAck1 mediated AKT/PKB tyrosine 176 phosphorylation regulates its activationActive-site inhibitors of mTOR target rapamycin-resistant outputs of mTORC1 and mTORC2A phosphoinositide 3-kinase/phospholipase Cgamma1 pathway regulates fibroblast growth factor-induced capillary tube formationRegulation of AKT phosphorylation at Ser473 and Thr308 by endoplasmic reticulum stress modulates substrate specificity in a severity dependent mannerBRAT1 deficiency causes increased glucose metabolism and mitochondrial malfunctionSecond AKT: the rise of SGK in cancer signallingAkt augments the oncogenic potential of the HBx protein of hepatitis B virus by phosphorylationP90 RSK arranges Chk1 in the nucleus for monitoring of genomic integrity during cell proliferationLRRK2 directly phosphorylates Akt1 as a possible physiological substrate: impairment of the kinase activity by Parkinson's disease-associated mutationsCopine1 enhances neuronal differentiation of the hippocampal progenitor HiB5 cellsScribble-mediated membrane targeting of PHLPP1 is required for its negative regulation of AktShepherding AKT and androgen receptor by Ack1 tyrosine kinaseSREBP activity is regulated by mTORC1 and contributes to Akt-dependent cell growthEphA2 mediates ligand-dependent inhibition and ligand-independent promotion of cell migration and invasion via a reciprocal regulatory loop with AktAnkrd2/ARPP is a novel Akt2 specific substrate and regulates myogenic differentiation upon cellular exposure to H(2)O(2)A role for the CHC22 clathrin heavy-chain isoform in human glucose metabolismClipR-59 interacts with Akt and regulates Akt cellular compartmentalizationPar-4 inhibits Akt and suppresses Ras-induced lung tumorigenesisc-Src regulates Akt signaling in response to ghrelin via beta-arrestin signaling-independent and -dependent mechanismsThe Potential Role of BRCA1-Associated ATM Activator-1 (BRAT1) in Regulation of mTORDifferential 14-3-3 affinity capture reveals new downstream targets of phosphatidylinositol 3-kinase signalingAkt kinase targets the association of CBP with histone H3 to regulate the acetylation of lysine K18Phosphoinositide 3-kinase/Akt inhibits MST1-mediated pro-apoptotic signaling through phosphorylation of threonine 120New role for the protein tyrosine phosphatase DEP-1 in Akt activation and endothelial cell survivalPTEN suppresses the oncogenic function of AIB1 through decreasing its protein stability via mechanism involving Fbw7 alphaProtein kinase A-mediated 14-3-3 association impedes human Dapper1 to promote dishevelled degradationGOLPH3 modulates mTOR signalling and rapamycin sensitivity in cancerTrypanosoma cruzi targets Akt in host cells as an intracellular antiapoptotic strategyProtein kinases and phosphatases in the control of cell fateHepatitis C virus differentially modulates activation of forkhead transcription factors and insulin-induced metabolic gene expressionUpdates of mTOR inhibitorsmTOR inhibitors in advanced renal cell carcinomaThe Skp2-SCF E3 ligase regulates Akt ubiquitination, glycolysis, herceptin sensitivity, and tumorigenesisThe Ras-ERK and PI3K-mTOR pathways: cross-talk and compensationTargeting mTOR for the treatment of AML. New agents and new directionsThe substrates and binding partners of protein kinase CepsilonPHLiPPing the switch on Akt and protein kinase C signaling
P2860
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P2860
description
2007 nî lūn-bûn
@nan
2007 թուականի Յունիսին հրատարակուած գիտական յօդուած
@hyw
2007 թվականի հունիսին հրատարակված գիտական հոդված
@hy
2007年の論文
@ja
2007年論文
@yue
2007年論文
@zh-hant
2007年論文
@zh-hk
2007年論文
@zh-mo
2007年論文
@zh-tw
2007年论文
@wuu
name
AKT/PKB signaling: navigating downstream
@ast
AKT/PKB signaling: navigating downstream
@en
AKT/PKB signaling: navigating downstream
@nl
type
label
AKT/PKB signaling: navigating downstream
@ast
AKT/PKB signaling: navigating downstream
@en
AKT/PKB signaling: navigating downstream
@nl
prefLabel
AKT/PKB signaling: navigating downstream
@ast
AKT/PKB signaling: navigating downstream
@en
AKT/PKB signaling: navigating downstream
@nl
P2860
P3181
P1433
P1476
AKT/PKB signaling: navigating downstream
@en
P2093
Brendan D Manning
P2860
P304
P3181
P356
10.1016/J.CELL.2007.06.009
P407
P577
2007-06-29T00:00:00Z