DNA damage checkpoint and recombinational repair differentially affect the replication stress tolerance of Smc6 mutants. - Test2 - elhamkhani - TriplyDB

DNA damage checkpoint and recombinational repair differentially affect the replication stress tolerance of Smc6 mutants.

DNA damage checkpoint and recombinational repair differentially affect the replication stress tolerance of Smc6 mutants.

http://www.wikidata.org/entity/Q37056627

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Functions and regulation of the multitasking FANCM family of DNA motor proteins Mte1 interacts with Mph1 and promotes crossover recombination and telomere maintenance.A versatile scaffold contributes to damage survival via sumoylation and nuclease interactions Rtt107 Is a Multi-functional Scaffold Supporting Replication Progression with Partner SUMO and Ubiquitin Ligases.MTE1 Functions with MPH1 in Double-Strand Break Repair.Incision of damaged DNA in the presence of an impaired Smc5/6 complex imperils genome stability Smc5/6-mediated regulation of replication progression contributes to chromosome assembly during mitosis in human cells.Smc5/6 Mediated Sumoylation of the Sgs1-Top3-Rmi1 Complex Promotes Removal of Recombination Intermediates.The Slx4-Dpb11 scaffold complex: coordinating the response to replication fork stalling in S-phase and the subsequent mitosis.Acute Smc5/6 depletion reveals its primary role in rDNA replication by restraining recombination at fork pausing sites.

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DNA damage checkpoint and recombinational repair differentially affect the replication stress tolerance of Smc6 mutants.

http://www.wikidata.org/entity/Q37056627

description

article científic

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article scientifique

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articolo scientifico

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artigo científico

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bilimsel makale

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scientific article published on 19 June 2013

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vedecký článok

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vetenskaplig artikel

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videnskabelig artikel

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vědecký článek

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DNA damage checkpoint and reco ...... ess tolerance of Smc6 mutants.

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DNA damage checkpoint and reco ...... ess tolerance of Smc6 mutants.

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DNA damage checkpoint and reco ...... ess tolerance of Smc6 mutants.

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DNA damage checkpoint and reco ...... ess tolerance of Smc6 mutants.

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prefLabel

DNA damage checkpoint and reco ...... ess tolerance of Smc6 mutants.

@en

DNA damage checkpoint and reco ...... ess tolerance of Smc6 mutants.

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MBC.E12-11-0836

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Molecular Biology of the Cell

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DNA damage checkpoint and reco ...... ess tolerance of Smc6 mutants.

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Federica Castellucci

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Yu-Hung Chen

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P2860

Coordination of DNA damage responses via the Smc5/Smc6 complex

Homologous recombination in DNA repair and DNA damage tolerance

A SUMO ligase is part of a nuclear multiprotein complex that affects DNA repair and chromosomal organization

Ubc9- and mms21-mediated sumoylation counteracts recombinogenic events at damaged replication forks.

Interplay between the Smc5/6 complex and the Mph1 helicase in recombinational repair

Sumoylation and the structural maintenance of chromosomes (Smc) 5/6 complex slow senescence through recombination intermediate resolution.

The Dun1 checkpoint kinase phosphorylates and regulates the ribonucleotide reductase inhibitor Sml1.

The yeast Shu complex couples error-free post-replication repair to homologous recombination.

Esc2 and Sgs1 act in functionally distinct branches of the homologous recombination repair pathway in Saccharomyces cerevisiae.

A suppressor of two essential checkpoint genes identifies a novel protein that negatively affects dNTP pools.

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2431-2441

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scholarly article

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10.1091/MBC.E12-11-0836

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15

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24

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Barnabas Szakal

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2013-06-19T00:00:00Z

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23783034

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3727935

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