Interactions between human cytomegalovirus IE1-72 and cellular p107: functional domains and mechanisms of up-regulation of cyclin E/cdk2 kinase activity.

Interactions between human cytomegalovirus IE1-72 and cellular p107: functional domains and mechanisms of up-regulation of cyclin E/cdk2 kinase activity.

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http://www.wikidata.org/entity/Q37060045
B55alpha PP2A holoenzymes modulate the phosphorylation status of the retinoblastoma-related protein p107 and its activationThe DNA damage response induced by infection with human cytomegalovirus and other virusesExon 3 of the human cytomegalovirus major immediate-early region is required for efficient viral gene expression and for cellular cyclin modulation.Human cytomegalovirus IE1-72 activates ataxia telangiectasia mutated kinase and a p53/p21-mediated growth arrest responsePolycomb repressive complex 2 targets murine cytomegalovirus chromatin for modification and associates with viral replication centers.Evidence that the human cytomegalovirus IE2-86 protein binds mdm2 and facilitates mdm2 degradationTranscriptional activation of endoplasmic reticulum chaperone GRP78 by HCMV IE1-72 proteinHuman cytomegalovirus UL97 kinase activity is required for the hyperphosphorylation of retinoblastoma protein and inhibits the formation of nuclear aggresomes.Cell cycle-independent expression of immediate-early gene 3 results in G1 and G2 arrest in murine cytomegalovirus-infected cells.Binding STAT2 by the acidic domain of human cytomegalovirus IE1 promotes viral growth and is negatively regulated by SUMO.Human cytomegalovirus IE1 protein enhances herpes simplex virus type 1-induced syncytial formation in U373MG cells.Regulation of the retinoblastoma proteins by the human herpesviruses.Human cytomegalovirus IE1-72 protein interacts with p53 and inhibits p53-dependent transactivation by a mechanism different from that of IE2-86 proteinIdentification of cellular proteins that interact with human cytomegalovirus immediate-early protein 1 by protein array assay.The human cytomegalovirus major immediate-early proteins as antagonists of intrinsic and innate antiviral host responses.Cytomegalovirus and glioma: putting the cart before the horse.The carboxyl-terminal region of human cytomegalovirus IE1491aa contains an acidic domain that plays a regulatory role and a chromatin-tethering domain that is dispensable during viral replication.
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Interactions between human cytomegalovirus IE1-72 and cellular p107: functional domains and mechanisms of up-regulation of cyclin E/cdk2 kinase activity.

Item
http://www.wikidata.org/entity/Q37060045
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on December 2003
@en
vedecký článok
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vetenskaplig artikel
@sv
videnskabelig artikel
@da
vědecký článek
@cs
name
Interactions between human cyt ...... cyclin E/cdk2 kinase activity.
@en
Interactions between human cyt ...... cyclin E/cdk2 kinase activity.
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type
label
Interactions between human cyt ...... cyclin E/cdk2 kinase activity.
@en
Interactions between human cyt ...... cyclin E/cdk2 kinase activity.
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prefLabel
Interactions between human cyt ...... cyclin E/cdk2 kinase activity.
@en
Interactions between human cyt ...... cyclin E/cdk2 kinase activity.
@nl
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Interactions between human cyt ...... cyclin E/cdk2 kinase activity.
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10.1128/JVI.77.23.12660-12670.2003
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