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Structures of Minimal Catalytic Fragments of Topoisomerase V Reveals Conformational Changes Relevant for DNA BindingIdentification of one of the apurinic/apyrimidinic lyase active sites of topoisomerase V by structural and functional studiesDecatenation of DNA by the S. cerevisiae Sgs1-Top3-Rmi1 and RPA complex: a mechanism for disentangling chromosomes.Metal ion and inter-domain interactions as functional networks in E. coli topoisomerase I.DNA-catalyzed serine side chain reactivity and selectivity.Transcription blockage by bulky end termini at single-strand breaks in the DNA template: differential effects of 5' and 3' adducts.Single-molecule analysis uncovers the difference between the kinetics of DNA decatenation by bacterial topoisomerases I and III.Biochemical characterization of the topoisomerase domain of Methanopyrus kandleri topoisomerase V.Crystal structure of a covalent intermediate in DNA cleavage and rejoining by Escherichia coli DNA topoisomerase I.DNA-catalyzed covalent modification of amino acid side chains in tethered and free peptide substrates.Escherichia coli topoisomerase I is an iron and zinc binding protein.Use of double-stranded DNA mini-circles to characterize the covalent topoisomerase-DNA complex.Residues of E. coli topoisomerase I conserved for interaction with a specific cytosine base to facilitate DNA cleavage.Bacterial topoisomerase I and topoisomerase III relax supercoiled DNA via distinct pathways.Structural basis for suppression of hypernegative DNA supercoiling by E. coli topoisomerase IMethanopyrus kandleri topoisomerase V contains three distinct AP lyase active sites in addition to the topoisomerase active site.Phytochemicals as Anticancer and Chemopreventive Topoisomerase II Poisons.Challenges and opportunities in developing novel drugs for TB.Structural basis of the interaction between Topoisomerase IIIβ and the TDRD3 auxiliary factorThe Effect of Dimethyl Sulfoxide on Supercoiled DNA Relaxation Catalyzed by Type I Topoisomerases.PprA contributes to Deinococcus radiodurans resistance to nalidixic acid, genome maintenance after DNA damage and interacts with deinococcal topoisomerases.Variola type IB DNA topoisomerase: DNA binding and supercoil unwinding using engineered DNA minicircles.An orthogonal single-molecule experiment reveals multiple-attempt dynamics of type IA topoisomerases.Topo2008: DNA topoisomerases in biology and medicine.Distinct Mechanism Evolved for Mycobacterial RNA Polymerase and Topoisomerase I Protein-Protein Interaction.Single-Molecule Magnetic Tweezer Analysis of Topoisomerases.Evidence for Inhibition of Topoisomerase 1A by Gold(III) Macrocycles and Chelates Targeting Mycobacterium tuberculosis and Mycobacterium abscessus.Biochemical Basis of E. coli Topoisomerase I Relaxation Activity Reduction by Nonenzymatic Lysine Acetylation.Arginine methylation of the C-terminus RGG motif promotes TOP3B topoisomerase activity and stress granule localization.
P2860
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P2860
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on 23 December 2008
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
@da
vědecký článek
@cs
name
Structural studies of type I topoisomerases.
@en
Structural studies of type I topoisomerases.
@nl
type
label
Structural studies of type I topoisomerases.
@en
Structural studies of type I topoisomerases.
@nl
prefLabel
Structural studies of type I topoisomerases.
@en
Structural studies of type I topoisomerases.
@nl
P2093
P2860
P921
P356
P1476
Structural studies of type I topoisomerases.
@en
P2093
Alfonso Mondragón
Nicole M Baker
Rakhi Rajan
P2860
P304
P356
10.1093/NAR/GKN1009
P407
P577
2008-12-23T00:00:00Z
2009-02-01T00:00:00Z