The origins of diversity and specificity in g protein-coupled receptor signaling
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Long-term artificial sweetener acesulfame potassium treatment alters neurometabolic functions in C57BL/6J miceG protein-coupled receptors in the hypothalamic paraventricular and supraoptic nuclei--serpentine gateways to neuroendocrine homeostasisTargeting G protein coupled receptor-related pathways as emerging molecular therapiesSystems-Level G Protein-Coupled Receptor Therapy Across a Neurodegenerative Continuum by the GLP-1 Receptor SystemNon-traditional roles of G protein-coupled receptors in basic cell biologyModifying ligand-induced and constitutive signaling of the human 5-HT4 receptorVENNTURE--a novel Venn diagram investigational tool for multiple pharmacological dataset analysisRepetitive peroxide exposure reveals pleiotropic mitogen-activated protein kinase signaling mechanismsStructure and dynamics of DRD4 bound to an agonist and an antagonist using in silico approaches.Lack of effect of the alpha2C-adrenoceptor Del322-325 polymorphism on inhibition of cyclic AMP production in HEK293 cells.Resolvin E1 receptor activation signals phosphorylation and phagocytosis.Plurigon: three dimensional visualization and classification of high-dimensionality data.Tyrosine phosphorylation of Kir3 following kappa-opioid receptor activation of p38 MAPK causes heterologous desensitizationChemical modification of class II G protein-coupled receptor ligands: frontiers in the development of peptide analogs as neuroendocrine pharmacological therapiesAn evolutionarily conserved arginine is essential for Tre1 G protein-coupled receptor function during germ cell migration in Drosophila melanogasterPharmacomimetics of exercise: novel approaches for hippocampally-targeted neuroprotective agents.Beyond desensitization: physiological relevance of arrestin-dependent signaling.ss-TEA: Entropy based identification of receptor specific ligand binding residues from a multiple sequence alignment of class A GPCRs.Gonadotropin-releasing hormone receptor system: modulatory role in aging and neurodegeneration.The mammalian tachykinin ligand-receptor system: an emerging target for central neurological disordersHeterologous regulation of Mu-opioid (MOP) receptor mobility in the membrane of SH-SY5Y cells.Complex and multidimensional lipid raft alterations in a murine model of Alzheimer's diseaseDiscontinuous pH gradient-mediated separation of TiO2-enriched phosphopeptides.G-protein-coupled receptor phosphorylation: where, when and by whom.Low-dose levodopa protects nerve cells from oxidative stress and up-regulates expression of pCREB and CD39Delineation of a conserved arrestin-biased signaling repertoire in vivo.'Biasing' the parathyroid hormone receptor: a novel anabolic approach to increasing bone mass?To be or not to be--obese.Pharmacological characterization of mGlu1 receptors in cerebellar granule cells reveals biased agonism.Mechanisms of ligand binding to the parathyroid hormone (PTH)/PTH-related protein receptor: selectivity of a modified PTH(1-15) radioligand for GalphaS-coupled receptor conformationsAllosteric modulation of seven transmembrane spanning receptors: theory, practice, and opportunities for central nervous system drug discoveryFulfilling the Promise of "Biased" G Protein-Coupled Receptor Agonism.Informatic deconvolution of biased GPCR signaling mechanisms from in vivo pharmacological experimentation.Understanding the Role of GPCR Heteroreceptor Complexes in Modulating the Brain Networks in Health and DiseaseAdenosine mediated desensitization of cAMP signaling enhances T-cell responses.Genetic variation in G-protein-coupled receptors--consequences for G-protein-coupled receptors as drug targets.Advances in receptor conformation research: the quest for functionally selective conformations focusing on the β2-adrenoceptorBioinformatic approaches to metabolic pathways analysis.G(q/11)α and G(s)α mediate distinct physiological responses to central melanocortinsAllosteric modulation of metabotropic glutamate receptor 4 activates IDO1-dependent, immunoregulatory signaling in dendritic cells.
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The origins of diversity and specificity in g protein-coupled receptor signaling
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on April 2005
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
@da
vědecký článek
@cs
name
The origins of diversity and specificity in g protein-coupled receptor signaling
@en
The origins of diversity and specificity in g protein-coupled receptor signaling.
@nl
type
label
The origins of diversity and specificity in g protein-coupled receptor signaling
@en
The origins of diversity and specificity in g protein-coupled receptor signaling.
@nl
prefLabel
The origins of diversity and specificity in g protein-coupled receptor signaling
@en
The origins of diversity and specificity in g protein-coupled receptor signaling.
@nl
P2860
P356
P1476
The origins of diversity and specificity in g protein-coupled receptor signaling
@en
P2093
Bronwen Martin
Stuart Maudsley
P2860
P304
P356
10.1124/JPET.105.083121
P407
P577
2005-04-01T00:00:00Z