Fulfilling the Promise of "Biased" G Protein-Coupled Receptor Agonism.
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G Protein-Coupled Receptors (GPCRs) in Alzheimer's Disease: A Focus on BACE1 Related GPCRsCardiovascular Dysfunction Following Burn Injury: What We Have Learned from Rat and Mouse ModelsSynthetic and Receptor Signaling Explorations of the Mitragyna Alkaloids: Mitragynine as an Atypical Molecular Framework for Opioid Receptor ModulatorsMapping Cannabinoid 1 Receptor Allosteric Site(s): Critical Molecular Determinant and Signaling Profile of GAT100, a Novel, Potent, and Irreversibly Binding Probe.Microvascular vasodilator properties of the angiotensin II type 2 receptor in a mouse model of type 1 diabetes.Functional Characterization of a Novel Series of Biased Signaling Dopamine D3 Receptor Agonists.Synthetic Studies of Neoclerodane Diterpenes from Salvia divinorum: Identification of a Potent and Centrally Acting μ Opioid Analgesic with Reduced Abuse Liability.Agonism, Antagonism, and Inverse Agonism Bias at the Ghrelin Receptor SignalingGIT2 Acts as a Systems-Level Coordinator of Neurometabolic Activity and Pathophysiological Aging.Stalk-dependent and Stalk-independent Signaling by the Adhesion G Protein-coupled Receptors GPR56 (ADGRG1) and BAI1 (ADGRB1)A G Protein-biased Designer G Protein-coupled Receptor Useful for Studying the Physiological Relevance of Gq/11-dependent Signaling Pathways.A Novel Allosteric Activator of Free Fatty Acid 2 Receptor Displays Unique Gi-functional BiasSeeking (and Finding) Biased Ligands of the Kappa Opioid Receptor.Biased agonism: An emerging paradigm in GPCR drug discovery.β-Adrenergic modulation of cancer cell proliferation: available evidence and clinical perspectives.Biased Type 1 Cannabinoid Receptor Signaling Influences Neuronal Viability in a Cell Culture Model of Huntington Disease.Metabolic Actions of the Type 1 Cholecystokinin Receptor: Its Potential as a Therapeutic Target.Discriminative Stimulus Properties of Opioid Ligands: Progress and Future Directions.The Follitropin Receptor: Matching Structure and Function.Allosteric communication pipelines in G-protein-coupled receptors.Gβγ Pathways in Cell Polarity and Migration Linked to Oncogenic GPCR Signaling: Potential Relevance in Tumor Microenvironment.G Protein-Coupled Receptor Endosomal Signaling and Regulation of Neuronal Excitability and Stress Responses: Signaling Options and Lessons From the PAC1 Receptor.Functional selectivity at G-protein coupled receptors: Advancing cannabinoid receptors as drug targets.Arresting the Development of Addiction: The Role of β-Arrestin 2 in Drug Abuse.Translating in vitro ligand bias into in vivo efficacy.The Diverse Roles of Arrestin Scaffolds in G Protein-Coupled Receptor Signaling.Opportunities for therapeutic antibodies directed at G-protein-coupled receptors.Structurally related odorant ligands of the olfactory receptor OR51E2 differentially promote metastasis emergence and tumor growthProstaglandin E2 glyceryl ester is an endogenous agonist of the nucleotide receptor P2Y6Systematic errors in detecting biased agonism: Analysis of current methods and development of a new model-free approach.Sequence-Specific Regulation of Endocytic Lifetimes Modulates Arrestin-Mediated Signaling at the µ Opioid Receptor.Modulation of opioid receptor affinity and efficacy via N-substitution of 9β-hydroxy-5-(3-hydroxyphenyl)morphan: Synthesis and computer simulation study.Female-specific myoinhibitory peptide neurons regulate mating receptivity in Drosophila melanogaster.Biased signalling: from simple switches to allosteric microprocessors.Biased signaling of the proton-sensing receptor OGR1 by benzodiazepines.A novel fibroblast growth factor-1 ligand with reduced heparin binding protects the heart against ischemia-reperfusion injury in the presence of heparin co-administration.Investigating Internalization and Intracellular Trafficking of GPCRs: New Techniques and Real-Time Experimental Approaches.Medications for substance use disorders (SUD): emerging approaches.Pharmacological Chaperones as Potential Therapeutic Strategies for Misfolded Mutant Vasopressin Receptors.Activation processes in ligand-activated G protein-coupled receptors: A case study of the adenosine A2A receptor.
P2860
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P2860
Fulfilling the Promise of "Biased" G Protein-Coupled Receptor Agonism.
description
2015 nî lūn-bûn
@nan
2015年の論文
@ja
2015年論文
@yue
2015年論文
@zh-hant
2015年論文
@zh-hk
2015年論文
@zh-mo
2015年論文
@zh-tw
2015年论文
@wuu
2015年论文
@zh
2015年论文
@zh-cn
name
Fulfilling the Promise of "Biased" G Protein-Coupled Receptor Agonism.
@ast
Fulfilling the Promise of "Biased" G Protein-Coupled Receptor Agonism.
@en
type
label
Fulfilling the Promise of "Biased" G Protein-Coupled Receptor Agonism.
@ast
Fulfilling the Promise of "Biased" G Protein-Coupled Receptor Agonism.
@en
prefLabel
Fulfilling the Promise of "Biased" G Protein-Coupled Receptor Agonism.
@ast
Fulfilling the Promise of "Biased" G Protein-Coupled Receptor Agonism.
@en
P2860
P356
P1476
Fulfilling the Promise of "Biased" G Protein-Coupled Receptor Agonism
@en
P2093
Laura M Bohn
Stuart Maudsley
P2860
P304
P356
10.1124/MOL.115.099630
P577
2015-07-01T00:00:00Z