Transcriptional targets of sirtuins in the coordination of mammalian physiology
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Enzymes in the NAD+ salvage pathway regulate SIRT1 activity at target gene promotersSirtuins as regulators of metabolism and healthspanOxidative stress and epigenetic regulation in ageing and age-related diseasesSenescence in adipose-derived stem cells and its implications in nerve regenerationCREB and ChREBP oppositely regulate SIRT1 expression in response to energy availabilityMir-34a mimics are potential therapeutic agents for p53-mutated and chemo-resistant brain tumour cellsTang-Nai-Kang alleviates pre-diabetes and metabolic disorders and induces a gene expression switch toward fatty acid oxidation in SHR.Cg-Leprcp/NDmcr ratsRole of SIRT1 in regulation of LPS- or two ethanol metabolites-induced TNF-alpha production in cultured macrophage cell linesNicotinamide, NAD(P)(H), and Methyl-Group Homeostasis Evolved and Became a Determinant of Ageing Diseases: Hypotheses and Lessons from PellagraRecent progress in the biology and physiology of sirtuinsOpposing effects of sirtuins on neuronal survival: SIRT1-mediated neuroprotection is independent of its deacetylase activityResveratrol, an activator of SIRT1, upregulates sarcoplasmic calcium ATPase and improves cardiac function in diabetic cardiomyopathyAdaptations to High Salt in a Halophilic Protist: Differential Expression and Gene Acquisitions through Duplications and Gene TransfersThe secret life of NAD+: an old metabolite controlling new metabolic signaling pathways.DOT1L safeguards cartilage homeostasis and protects against osteoarthritis.Conserved role of SIRT1 orthologs in fasting-dependent inhibition of the lipid/cholesterol regulator SREBP.Metabolism and the circadian clock converge.Age-associated changes in oxidative stress and NAD+ metabolism in human tissue.Regulation of SIRT1 in vascular smooth muscle cells from streptozotocin-diabetic ratsAge-dependent regulation of skeletal muscle mitochondria by the thrombospondin-1 receptor CD47.Resveratrol attenuates diabetic nephropathy via modulating angiogenesis.Distinct effects of calorie restriction and resveratrol on diet-induced obesity and Fatty liver formationSIRT1 is essential for oncogenic signaling by estrogen/estrogen receptor α in breast cancerRegulation of Cell Cycle Regulators by SIRT1 Contributes to Resveratrol-Mediated Prevention of Pulmonary Arterial Hypertension.Role and treatment of mitochondrial DNA-related mitochondrial dysfunction in sporadic neurodegenerative diseases.Deacetylation-mediated interaction of SIRT1-HMGB1 improves survival in a mouse model of endotoxemia.Ligand-activated peroxisome proliferator-activated receptor-δ and -γ inhibit lipopolysaccharide-primed release of high mobility group box 1 through upregulation of SIRT1Protein deacetylation by SIRT1: an emerging key post-translational modification in metabolic regulationAMP-activated protein kinase and its downstream transcriptional pathwaysRegulation of SREBP-Mediated Gene Expression.SIRT1 increases YAP- and MKK3-dependent p38 phosphorylation in mouse liver and human hepatocellular carcinoma.Comparing and contrasting the roles of AMPK and SIRT1 in metabolic tissues.Transcription factor NFκB regulates the expression of the histone deacetylase SIRT1Distinct effects of SIRT1 in cancer and stromal cells on tumor promotion.Epigenetics and the control of epithelial sodium channel expression in collecting duct.Sirtuin 1 functionally and physically interacts with disruptor of telomeric silencing-1 to regulate alpha-ENaC transcription in collecting duct.NMNATs, evolutionarily conserved neuronal maintenance factors.The emerging characterization of lysine residue deacetylation on the modulation of mitochondrial function and cardiovascular biology.Adiponectin: a key adipokine in alcoholic fatty liver.Caloric restriction, SIRT1 and longevity
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Transcriptional targets of sirtuins in the coordination of mammalian physiology
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on 28 May 2008
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
@da
vědecký článek
@cs
name
Transcriptional targets of sirtuins in the coordination of mammalian physiology
@en
Transcriptional targets of sirtuins in the coordination of mammalian physiology.
@nl
type
label
Transcriptional targets of sirtuins in the coordination of mammalian physiology
@en
Transcriptional targets of sirtuins in the coordination of mammalian physiology.
@nl
prefLabel
Transcriptional targets of sirtuins in the coordination of mammalian physiology
@en
Transcriptional targets of sirtuins in the coordination of mammalian physiology.
@nl
P2860
P1476
Transcriptional targets of sirtuins in the coordination of mammalian physiology
@en
P2093
Jerome N Feige
P2860
P304
P356
10.1016/J.CEB.2008.03.012
P50
P577
2008-05-28T00:00:00Z