WWOX dysfunction induces sequential aggregation of TRAPPC6AΔ, TIAF1, tau and amyloid β, and causes apoptosis.
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HYAL-2-WWOX-SMAD4 Signaling in Cell Death and Anticancer ResponseHyaluronan activates Hyal-2/WWOX/Smad4 signaling and causes bubbling cell death when the signaling complex is overexpressed.Role of WW Domain-containing Oxidoreductase WWOX in Driving T Cell Acute Lymphoblastic Leukemia Maturation.Zfra restores memory deficits in Alzheimer's disease triple-transgenic mice by blocking aggregation of TRAPPC6AΔ, SH3GLB2, tau, and amyloid β, and inflammatory NF-κB activation.A cascade of protein aggregation bombards mitochondria for neurodegeneration and apoptosis under WWOX deficiency.Phosphorylation/de-phosphorylation in specific sites of tumor suppressor WWOX and control of distinct biological events.The immunoproteasome is induced by cytokines and regulates apoptosis in human islets.Chasing the signaling run by tri-molecular time-lapse FRET microscopy.WWOX Phosphorylation, Signaling, and Role in Neurodegeneration
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WWOX dysfunction induces sequential aggregation of TRAPPC6AΔ, TIAF1, tau and amyloid β, and causes apoptosis.
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article científic
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article scientifique
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articolo scientifico
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artigo científico
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bilimsel makale
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scientific article published on 03 August 2015
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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WWOX dysfunction induces seque ...... yloid β, and causes apoptosis.
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WWOX dysfunction induces seque ...... yloid β, and causes apoptosis.
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WWOX dysfunction induces seque ...... yloid β, and causes apoptosis.
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WWOX dysfunction induces seque ...... yloid β, and causes apoptosis.
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WWOX dysfunction induces seque ...... yloid β, and causes apoptosis.
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WWOX dysfunction induces seque ...... yloid β, and causes apoptosis.
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WWOX dysfunction induces seque ...... yloid β, and causes apoptosis.
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10.1038/CDDISCOVERY.2015.3
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2015-08-03T00:00:00Z