Transforming growth factor beta1 signaling via interaction with cell surface Hyal-2 and recruitment of WWOX/WOX1
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HYAL-2-WWOX-SMAD4 Signaling in Cell Death and Anticancer ResponseDramatic co-activation of WWOX/WOX1 with CREB and NF-kappaB in delayed loss of small dorsal root ganglion neurons upon sciatic nerve transection in ratsTGF-β induces TIAF1 self-aggregation via type II receptor-independent signaling that leads to generation of amyloid β plaques in Alzheimer's disease.Complement C1q activates tumor suppressor WWOX to induce apoptosis in prostate cancer cells.Diverse effect of WWOX overexpression in HT29 and SW480 colon cancer cell lines.Transforming growth factor beta receptor 2 (TGFBR2) changes sialylation in the microsatellite unstable (MSI) Colorectal cancer cell line HCT116WW domain-containing oxidoreductase in neuronal injury and neurological diseases.Identification of an In Vivo MEK/WOX1 Complex as a Master Switch for Apoptosis in T Cell Leukemia.Trafficking protein particle complex 6A delta (TRAPPC6AΔ) is an extracellular plaque-forming protein in the brain.Zfra activates memory Hyal-2+ CD3- CD19- spleen cells to block cancer growth, stemness, and metastasis in vivo.Emerging roles for hyaluronidase in cancer metastasis and therapy.UV irradiation/cold shock-mediated apoptosis is switched to bubbling cell death at low temperaturesTIAF1 self-aggregation in peritumor capsule formation, spontaneous activation of SMAD-responsive promoter in p53-deficient environment, and cell deathRole of WWOX and NF-κB in lung cancer progressionTumor Suppressor WWOX and p53 Alterations and Drug Resistance in Glioblastomas.Role of WW domain proteins WWOX in development, prognosis, and treatment response of glioma.Regulation of cell signaling and apoptosis by tumor suppressor WWOX.Roles of the WWOX in pathogenesis and endocrine therapy of breast cancer.Strategies of oncogenic microbes to deal with WW domain-containing oxidoreductaseBubbling cell death: A hot air balloon released from the nucleus in the coldWWOX dysfunction induces sequential aggregation of TRAPPC6AΔ, TIAF1, tau and amyloid β, and causes apoptosis.WWOX suppresses autophagy for inducing apoptosis in methotrexate-treated human squamous cell carcinomaHyaluronan activates Hyal-2/WWOX/Smad4 signaling and causes bubbling cell death when the signaling complex is overexpressed.Signaling from membrane receptors to tumor suppressor WW domain-containing oxidoreductase.Role of the WWOX tumor suppressor gene in bone homeostasis and the pathogenesis of osteosarcoma.Tyrosine phosphorylation of WW proteins.Two novel functions of hyaluronidase-2 (Hyal2) are formation of the glycocalyx and control of CD44-ERM interactionsFunctions and Epigenetic Regulation of Wwox in Bone Metastasis from Breast Carcinoma: Comparison with Primary Tumors.Self-aggregating TIAF1 in lung cancer progression.Hyaluronan regulates bone morphogenetic protein-7-dependent prevention and reversal of myofibroblast phenotype.Zfra induction of memory anticancer response via a novel immune cellRole of WW Domain-containing Oxidoreductase WWOX in Driving T Cell Acute Lymphoblastic Leukemia Maturation.Zfra restores memory deficits in Alzheimer's disease triple-transgenic mice by blocking aggregation of TRAPPC6AΔ, SH3GLB2, tau, and amyloid β, and inflammatory NF-κB activation.A cascade of protein aggregation bombards mitochondria for neurodegeneration and apoptosis under WWOX deficiency.Genetic and epigenetic alterations of WWOX in the development of gastric cardia adenocarcinoma.A Trickster in Disguise: Hyaluronan's Ambivalent Roles in the Matrix.Phosphorylation/de-phosphorylation in specific sites of tumor suppressor WWOX and control of distinct biological events.Hyal-1 but not Hyal-3 deficiency has an impact on ovarian folliculogenesis and female fertility by altering the follistatin/activin/Smad3 pathway and the apoptotic process.Chasing the signaling run by tri-molecular time-lapse FRET microscopy.WWOX Phosphorylation, Signaling, and Role in Neurodegeneration
P2860
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P248
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P2860
Transforming growth factor beta1 signaling via interaction with cell surface Hyal-2 and recruitment of WWOX/WOX1
description
2009 nî lūn-bûn
@nan
2009 թուականի Յունիսին հրատարակուած գիտական յօդուած
@hyw
2009 թվականի հունիսին հրատարակված գիտական հոդված
@hy
2009年の論文
@ja
2009年論文
@yue
2009年論文
@zh-hant
2009年論文
@zh-hk
2009年論文
@zh-mo
2009年論文
@zh-tw
2009年论文
@wuu
name
Transforming growth factor bet ...... 2 and recruitment of WWOX/WOX1
@ast
Transforming growth factor bet ...... 2 and recruitment of WWOX/WOX1
@en
Transforming growth factor bet ...... 2 and recruitment of WWOX/WOX1
@en-gb
Transforming growth factor bet ...... 2 and recruitment of WWOX/WOX1
@nl
type
label
Transforming growth factor bet ...... 2 and recruitment of WWOX/WOX1
@ast
Transforming growth factor bet ...... 2 and recruitment of WWOX/WOX1
@en
Transforming growth factor bet ...... 2 and recruitment of WWOX/WOX1
@en-gb
Transforming growth factor bet ...... 2 and recruitment of WWOX/WOX1
@nl
prefLabel
Transforming growth factor bet ...... 2 and recruitment of WWOX/WOX1
@ast
Transforming growth factor bet ...... 2 and recruitment of WWOX/WOX1
@en
Transforming growth factor bet ...... 2 and recruitment of WWOX/WOX1
@en-gb
Transforming growth factor bet ...... 2 and recruitment of WWOX/WOX1
@nl
P2093
P2860
P921
P356
P1476
Transforming growth factor bet ...... 2 and recruitment of WWOX/WOX1
@en
P2093
Cheng-Peng Lo
Feng-Jie Lai
John Heath
Kris Van Moer
Li-Jin Hsu
Lori Schultz
Meng-Yen Li
Ming-Hui Lee
Nan-Shan Chang
Qunying Hong
P2860
P304
P356
10.1074/JBC.M806688200
P407
P577
2009-06-05T00:00:00Z