Reducing sphingolipid synthesis orchestrates global changes to extend yeast lifespan.
about
The protein kinase Sch9 is a key regulator of sphingolipid metabolism in Saccharomyces cerevisiae.Drug synergy drives conserved pathways to increase fission yeast lifespanSix plant extracts delay yeast chronological aging through different signaling pathwaysMechanisms underlying the anti-aging and anti-tumor effects of lithocholic bile acidThe retrograde response: a conserved compensatory reaction to damage from within and from without.Sphingolipid metabolism regulates development and lifespan in Caenorhabditis elegans.Autophagy in the light of sphingolipid metabolismMitochondria to nucleus signaling and the role of ceramide in its integration into the suite of cell quality control processes during agingAltered Lipid Synthesis by Lack of Yeast Pah1 Phosphatidate Phosphatase Reduces Chronological Life Span.Aging-related elevation of sphingoid bases shortens yeast chronological life span by compromising mitochondrial functionTethering telomerase to telomeres increases genome instability and promotes chronological aging in yeastSphingolipids and lifespan regulation.Sphingolipid signalling mediates mitochondrial dysfunctions and reduced chronological lifespan in the yeast model of Niemann-Pick type C1.Sphingolipids and mitochondrial function, lessons learned from yeastExploring the power of yeast to model aging and age-related neurodegenerative disorders.Current Perspective in the Discovery of Anti-aging Agents from Natural Products.Sch9 regulates intracellular protein ubiquitination by controlling stress responses.Loss of Sphingosine Kinase Alters Life History Traits and Locomotor Function in Caenorhabditis elegans.Sphingolipid accumulation causes mitochondrial dysregulation and cell death.Sphingolipids facilitate age asymmetry of membrane proteins in dividing yeast cells.Emerging roles for sphingolipids in cellular aging.Sulfur restriction extends fission yeast chronological lifespan through Ecl1 family genes by downregulation of ribosome.Some Metabolites Act as Second Messengers in Yeast Chronological Aging.
P2860
Q27935105-15634ACE-75EF-4DD9-AF5A-412E1624E381Q28544630-302AA373-21AE-41E9-8D4B-390C614A1B15Q28817161-1DA8934E-479B-41B6-A633-8CBAA767BFA7Q34358930-CD520F28-2670-47D7-988C-6DA6B6DE43E6Q34741848-903AF23D-2F04-4657-A367-426E28E8C012Q34938909-04EE15C0-80D7-4C24-A9A7-209BF4A15B1FQ35225431-252E8E91-8B18-46CD-88D7-6DA6F893E4F5Q35779405-A37E591F-39DA-4127-A193-C6BB722F4090Q36283303-26B78CF8-81B8-4EC4-BA44-9458A7C3602CQ37225235-75C6CFF1-372D-435F-814B-9A9350671E8FQ37538214-134B8AF2-5EEF-4E71-8022-361520DCC3D5Q37586487-2801807B-8EB1-48A0-A343-22676ACBFBAFQ37638571-FFE9BBB2-2429-456A-B3E1-755F403009EEQ37698292-00E2B737-5CCF-4974-BACA-A06AC7BDE021Q38996403-3768DB2C-78E9-4E93-B538-EB5334626EA3Q39343002-B1B3D0F7-20A4-4002-B2C4-80816A459785Q41879437-3308E3EE-30ED-4E2F-AE24-2DB52D670CBEQ41952712-9EEC6176-1CA9-4B43-BE43-2D18953C95BBQ46322324-54286B8D-ADCD-44A7-B92D-6F3131C1F4FCQ47219042-C514DFBE-8254-4CBD-A405-E5BFA33C5DA3Q47232843-E6707481-FFA3-4141-8EA6-5D100E6ED27CQ48303656-182DD980-2F00-4C49-AD27-434F97C39D12Q51762830-3A228836-1014-44C1-A594-1A76D482B198
P2860
Reducing sphingolipid synthesis orchestrates global changes to extend yeast lifespan.
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on 08 July 2013
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
@da
vědecký článek
@cs
name
Reducing sphingolipid synthesis orchestrates global changes to extend yeast lifespan.
@en
Reducing sphingolipid synthesis orchestrates global changes to extend yeast lifespan.
@nl
type
label
Reducing sphingolipid synthesis orchestrates global changes to extend yeast lifespan.
@en
Reducing sphingolipid synthesis orchestrates global changes to extend yeast lifespan.
@nl
prefLabel
Reducing sphingolipid synthesis orchestrates global changes to extend yeast lifespan.
@en
Reducing sphingolipid synthesis orchestrates global changes to extend yeast lifespan.
@nl
P2093
P2860
P356
P1433
P1476
Reducing sphingolipid synthesis orchestrates global changes to extend yeast lifespan.
@en
P2093
Bradley R Withers
Eric Blalock
Robert C Dickson
Xinhe Huang
P2860
P304
P356
10.1111/ACEL.12107
P577
2013-07-08T00:00:00Z