Enhancement of RAD51 recombinase activity by the tumor suppressor PALB2.
about
ChAM, a novel motif that mediates PALB2 intrinsic chromatin binding and facilitates DNA repairBreast cancer proteins PALB2 and BRCA2 stimulate polymerase η in recombination-associated DNA synthesis at blocked replication forksBreast cancer-associated missense mutants of the PALB2 WD40 domain, which directly binds RAD51C, RAD51 and BRCA2, disrupt DNA repairThe Knowns Unknowns: Exploring the Homologous Recombination Repair Pathway in Toxoplasma gondiiInteraction with PALB2 Is Essential for Maintenance of Genomic Integrity by BRCA2Homologous recombination and human health: the roles of BRCA1, BRCA2, and associated proteinsNUCKS1 is a novel RAD51AP1 paralog important for homologous recombination and genome stabilityUnraveling the mechanism of BRCA2 in homologous recombinationPALB2: the hub of a network of tumor suppressors involved in DNA damage responsesCooperation of breast cancer proteins PALB2 and piccolo BRCA2 in stimulating homologous recombinationPalb2 synergizes with Trp53 to suppress mammary tumor formation in a model of inherited breast cancerA genetic screen identifies BRCA2 and PALB2 as key regulators of G2 checkpoint maintenanceCancer-causing mutations in the tumor suppressor PALB2 reveal a novel cancer mechanism using a hidden nuclear export signal in the WD40 repeat motifCTCF facilitates DNA double-strand break repair by enhancing homologous recombination repair.Phosphorylated RPA recruits PALB2 to stalled DNA replication forks to facilitate fork recovery.Male fertility defect associated with disrupted BRCA1-PALB2 interaction in micePlasticity of BRCA2 function in homologous recombination: genetic interactions of the PALB2 and DNA binding domains.Structure and mechanism of action of the BRCA2 breast cancer tumor suppressorNon-catalytic Roles for XPG with BRCA1 and BRCA2 in Homologous Recombination and Genome StabilityS100A11 plays a role in homologous recombination and genome maintenance by influencing the persistence of RAD51 in DNA repair foci.RAD51 and breast cancer susceptibility: no evidence for rare variant association in the Breast Cancer Family Registry study.RAD51AP1-deficiency in vertebrate cells impairs DNA replication.Requirement of heterogeneous nuclear ribonucleoprotein C for BRCA gene expression and homologous recombination.Synthetic lethality of PARP inhibition in cancers lacking BRCA1 and BRCA2 mutations.Tumor-associated mutations in a conserved structural motif alter physical and biochemical properties of human RAD51 recombinase.Dual DNA-binding domains shape the interaction of Brh2 with DNA.Mechanistic insights into RAD51-associated protein 1 (RAD51AP1) action in homologous DNA repair.Homologous recombination and its regulationThe β-isoform of BCCIP promotes ADP release from the RAD51 presynaptic filament and enhances homologous DNA pairing.Roles for APRIN (PDS5B) in homologous recombination and in ovarian cancer prediction.ATM-dependent Phosphorylation of the Fanconi Anemia Protein PALB2 Promotes the DNA Damage Response.RS-1 enhances CRISPR/Cas9- and TALEN-mediated knock-in efficiencyMDC1 and RNF8 function in a pathway that directs BRCA1-dependent localization of PALB2 required for homologous recombinationPoly(ADP-Ribose) Mediates the BRCA2-Dependent Early DNA Damage Response.Prevalence of PALB2 mutations in Australasian multiple-case breast cancer familiesPALB2 and breast cancer: ready for clinical translation!Heterozygous PALB2 c.1592delT mutation channels DNA double-strand break repair into error-prone pathways in breast cancer patients.Small-molecule inhibitors identify the RAD52-ssDNA interaction as critical for recovery from replication stress and for survival of BRCA2 deficient cellsHeterozygous mutations in PALB2 cause DNA replication and damage response defects.PGC7 suppresses TET3 for protecting DNA methylation.
P2860
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P2860
Enhancement of RAD51 recombinase activity by the tumor suppressor PALB2.
description
2010 nî lūn-bûn
@nan
2010 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի սեպտեմբերին հրատարակված գիտական հոդված
@hy
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
name
Enhancement of RAD51 recombinase activity by the tumor suppressor PALB2
@nl
Enhancement of RAD51 recombinase activity by the tumor suppressor PALB2.
@ast
Enhancement of RAD51 recombinase activity by the tumor suppressor PALB2.
@en
Enhancement of RAD51 recombinase activity by the tumor suppressor PALB2.
@en-gb
type
label
Enhancement of RAD51 recombinase activity by the tumor suppressor PALB2
@nl
Enhancement of RAD51 recombinase activity by the tumor suppressor PALB2.
@ast
Enhancement of RAD51 recombinase activity by the tumor suppressor PALB2.
@en
Enhancement of RAD51 recombinase activity by the tumor suppressor PALB2.
@en-gb
prefLabel
Enhancement of RAD51 recombinase activity by the tumor suppressor PALB2
@nl
Enhancement of RAD51 recombinase activity by the tumor suppressor PALB2.
@ast
Enhancement of RAD51 recombinase activity by the tumor suppressor PALB2.
@en
Enhancement of RAD51 recombinase activity by the tumor suppressor PALB2.
@en-gb
P2093
P2860
P50
P921
P3181
P356
P1476
Enhancement of RAD51 recombinase activity by the tumor suppressor PALB2.
@en
P2093
Claudia Wiese
David Schild
Dongqing Liu
Dorina Saro
Eloïse Dray
Gareth J Williams
Julia Etchin
Junjie Chen
Miaw-Sheue Tsai
Michal Hammel
P2860
P2888
P304
P3181
P356
10.1038/NSMB.1916
P407
P577
2010-09-26T00:00:00Z
P5875
P6179
1010409975