Multiple roles for Sox2 in the developing and adult mouse trachea.
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Evidence that SOX2 overexpression is oncogenic in the lungPreparing for the first breath: genetic and cellular mechanisms in lung developmentStomach development, stem cells and diseaseLung Regeneration: Endogenous and Exogenous Stem Cell Mediated Therapeutic ApproachesNubp1 is required for lung branching morphogenesis and distal progenitor cell survival in miceDifferentiated type II pneumocytes can be reprogrammed by ectopic Sox2 expressionPulmonary adenocarcinoma: a renewed entity in 2011Lung epithelial branching program antagonizes alveolar differentiationRegulation of lung endoderm progenitor cell behavior by miR302/367Expression of NANOG and NANOGP8 in a variety of undifferentiated and differentiated human cells.Ontogeny of the mouse vocal fold epithelium.Gpr177 regulates pulmonary vasculature developmentSOX2 is an amplified lineage-survival oncogene in lung and esophageal squamous cell carcinomasCell lineage distribution atlas of the human stomach reveals heterogeneous gland populations in the gastric antrumBarx1-mediated inhibition of Wnt signaling in the mouse thoracic foregut controls tracheo-esophageal septation and epithelial differentiation.Sox2 is required for maintenance and differentiation of bronchiolar Clara, ciliated, and goblet cells.Sex determining region Y-Box 2 (SOX2) is a potential cell-lineage gene highly expressed in the pathogenesis of squamous cell carcinomas of the lung.Dual functions of ASCIZ in the DNA base damage response and pulmonary organogenesisSOX2 regulates acinar cell development in the salivary gland.Two nested developmental waves demarcate a compartment boundary in the mouse lungProgressive 3q amplification consistently targets SOX2 in preinvasive squamous lung cancer.Generation of multipotent lung and airway progenitors from mouse ESCs and patient-specific cystic fibrosis iPSCs.Developmental programs of lung epithelial progenitors: a balanced progenitor model.Sox2(+) adult stem and progenitor cells are important for tissue regeneration and survival of mice.Multiple roles and interactions of Tbx4 and Tbx5 in development of the respiratory system.Sox2 cooperates with Lkb1 loss in a mouse model of squamous cell lung cancer.Diseases of pulmonary surfactant homeostasis.Identification of a proximal progenitor population from murine fetal lungs with clonogenic and multilineage differentiation potential.Lung regeneration: mechanisms, applications and emerging stem cell populationsMiR-221 and miR-130a regulate lung airway and vascular developmentGene regulatory networks governing lung specification.Three-dimensional culture and FGF signaling drive differentiation of murine pluripotent cells to distal lung epithelial cells.Wnt/β-catenin signaling accelerates mouse lung tumorigenesis by imposing an embryonic distal progenitor phenotype on lung epithelium.Ezh2 represses the basal cell lineage during lung endoderm development.The three R's of lung health and disease: repair, remodeling, and regeneration.Akt increases sox2 expression in adult hippocampal neural progenitor cells, but increased sox2 does not promote proliferation.Sox2 activates cell proliferation and differentiation in the respiratory epithelium.Wnt and FGF mediated epithelial-mesenchymal crosstalk during lung development.Age-related changes in the cellular composition and epithelial organization of the mouse trachea.Intersections between pulmonary development and disease.
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Multiple roles for Sox2 in the developing and adult mouse trachea.
description
article científic
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article scientifique
@fr
articolo scientifico
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artigo científico
@pt
bilimsel makale
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scientific article published on 29 April 2009
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
Multiple roles for Sox2 in the developing and adult mouse trachea.
@en
Multiple roles for Sox2 in the developing and adult mouse trachea.
@nl
type
label
Multiple roles for Sox2 in the developing and adult mouse trachea.
@en
Multiple roles for Sox2 in the developing and adult mouse trachea.
@nl
prefLabel
Multiple roles for Sox2 in the developing and adult mouse trachea.
@en
Multiple roles for Sox2 in the developing and adult mouse trachea.
@nl
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P2860
P356
P1433
P1476
Multiple roles for Sox2 in the developing and adult mouse trachea.
@en
P2093
Brigid L M Hogan
Jianwen Que
Robert J Schwartz
Xiaoyan Luo
P2860
P304
P356
10.1242/DEV.034629
P407
P577
2009-04-29T00:00:00Z