Monocarboxylate transporters in the brain and in cancer. - Test2 - elhamkhani - TriplyDB

Monocarboxylate transporters in the brain and in cancer.

Monocarboxylate transporters in the brain and in cancer.

http://www.wikidata.org/entity/Q37187094

about

Lactate as a Metabolite and a Regulator in the Central Nervous System Radiosynthesis and validation of (±)-[18F]-3-fluoro-2-hydroxypropionate ([18F]-FLac) as a PET tracer of lactate to monitor MCT1-dependent lactate uptake in tumors Cancer heterogeneity is not compatible with one unique cancer cell metabolic map Stromal uptake and transmission of acid is a pathway for venting cancer cell-generated acid.Lactate Shuttles in Neuroenergetics-Homeostasis, Allostasis and Beyond.Early and Late Pathomechanisms in Alzheimer's Disease: From Zinc to Amyloid-β Neurotoxicity Monocarboxylate Transporters: Therapeutic Targets and Prognostic Factors in Disease.Cell-surface G-protein-coupled receptors for tumor-associated metabolites: A direct link to mitochondrial dysfunction in cancer.Heterogeneity of p53 dependent genomic responses following ethanol exposure in a developmental mouse model of fetal alcohol spectrum disorder.Lactate stimulates CA IX expression in normoxic cancer cells.An auditory brainstem nucleus as a model system for neuronal metabolic demands.Endothelial Cell Metabolism.Stromal-epithelial lactate shuttle induced by tumor‑derived interleukin‑1β promotes cell proliferation in oral squamous cell carcinoma.Metabolic Symbiosis and Immunomodulation: How Tumor Cell-Derived Lactate May Disturb Innate and Adaptive Immune Responses.Beta-hydroxybutyrate (3-OHB) can influence the energetic phenotype of breast cancer cells, but does not impact their proliferation and the response to chemotherapy or radiation.Short-Chain Fatty Acid Transporters: Role in Colonic Homeostasis.An overview of MCT1 and MCT4 in GBM: small molecule transporters with large implications

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P2860

Monocarboxylate transporters in the brain and in cancer.

http://www.wikidata.org/entity/Q37187094

description

article científic

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article scientifique

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articolo scientifico

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artigo científico

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bilimsel makale

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scientific article published on 15 March 2016

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vedecký článok

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vetenskaplig artikel

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videnskabelig artikel

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vědecký článek

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name

Monocarboxylate transporters in the brain and in cancer.

@en

Monocarboxylate transporters in the brain and in cancer.

@nl

type

label

Monocarboxylate transporters in the brain and in cancer.

@en

Monocarboxylate transporters in the brain and in cancer.

@nl

prefLabel

Monocarboxylate transporters in the brain and in cancer.

@en

Monocarboxylate transporters in the brain and in cancer.

@nl

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J.BBAMCR.2016.03.013

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Biochimica et Biophysica Acta

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Monocarboxylate transporters in the brain and in cancer

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Jhudit Pérez-Escuredo

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Jorge Falces

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Martina Sboarina

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Pierre Sonveaux

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Valéry L Payen

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Creative Commons Attribution-NonCommercial-NoDerivs 4.0 International

P2860

Lactate activates HIF-1 in oxidative but not in Warburg-phenotype human tumor cells

Hallmarks of Cancer: The Next Generation

Presence and localization of three lactic acid transporters (MCT1, -2, and -4) in separated human granulocytes, lymphocytes, and monocytes

The role of charged residues in the transmembrane helices of monocarboxylate transporter 1 and its ancillary protein basigin in determining plasma membrane expression and catalytic activity

Molecular characterization of a membrane transporter for lactate, pyruvate, and other monocarboxylates: implications for the Cori cycle

The proton-linked monocarboxylate transporter (MCT) family: structure, function and regulation

Understanding the Warburg effect: the metabolic requirements of cell proliferation

CD147 is tightly associated with lactate transporters MCT1 and MCT4 and facilitates their cell surface expression

Characterisation of human monocarboxylate transporter 4 substantiates its role in lactic acid efflux from skeletal muscle

Identification and characterization of a monocarboxylate transporter (MCT1) in pig and human colon: its potential to transport L-lactate as well as butyrate

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2481-2497

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10.1016/J.BBAMCR.2016.03.013

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Vincent F Van Hée

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