The role of charged residues in the transmembrane helices of monocarboxylate transporter 1 and its ancillary protein basigin in determining plasma membrane expression and catalytic activity
about
Hypoxia, cancer metabolism and the therapeutic benefit of targeting lactate/H(+) symportersThe inhibition of monocarboxylate transporter 2 (MCT2) by AR-C155858 is modulated by the associated ancillary proteinStudies on the DIDS-binding site of monocarboxylate transporter 1 suggest a homology model of the open conformation and a plausible translocation cycleAR-C155858 is a potent inhibitor of monocarboxylate transporters MCT1 and MCT2 that binds to an intracellular site involving transmembrane helices 7-10The monocarboxylate transporter family--Structure and functional characterization.The neuroplastin adhesion molecules are accessory proteins that chaperone the monocarboxylate transporter MCT2 to the neuronal cell surface.Insights into molecular properties of the human monocarboxylate transporter 8 by combining functional with structural information.Identification of key binding site residues of MCT1 for AR-C155858 reveals the molecular basis of its isoform selectivity.Unassembled CD147 is an endogenous endoplasmic reticulum-associated degradation substrateCD147-dependent heterogeneity in malignant and chemoresistant properties of cancer cellsOverview of the proton-coupled MCT (SLC16A) family of transporters: characterization, function and role in the transport of the drug of abuse gamma-hydroxybutyric acid.Gem-1 encodes an SLC16 monocarboxylate transporter-related protein that functions in parallel to the gon-2 TRPM channel during gonad development in Caenorhabditis elegans.Monocarboxylate transporters in the brain and in cancer.Xkr8 phospholipid scrambling complex in apoptotic phosphatidylserine exposure.Zinc- and bicarbonate-dependent ZIP8 transporter mediates selenite uptake.CD147: a small molecule transporter ancillary protein at the crossroad of multiple hallmarks of cancer and metabolic reprogramming.Cyclophilin-CD147 interactions: a new target for anti-inflammatory therapeutics.Primary and secondary thyroid hormone transporters.Monocarboxylic acid transport.The Neuroplastin adhesion molecules: key regulators of neuronal plasticity and synaptic function.Structure and function of thyroid hormone plasma membrane transporters.Monocarboxylate Transporters: Therapeutic Targets and Prognostic Factors in Disease.Evidence for a homodimeric structure of human monocarboxylate transporter 8.Type 2 Diabetes Variants Disrupt Function of SLC16A11 through Two Distinct Mechanisms.Essential molecular determinants for thyroid hormone transport and first structural implications for monocarboxylate transporter 8.Abnormal creatine transport of mutations in monocarboxylate transporter 12 (MCT12) found in patients with age-related cataract can be partially rescued by exogenous chaperone CD147.Lactic Acid: No Longer an Inert and End-Product of Glycolysis.Short-Chain Fatty Acid Transporters: Role in Colonic Homeostasis.
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P2860
The role of charged residues in the transmembrane helices of monocarboxylate transporter 1 and its ancillary protein basigin in determining plasma membrane expression and catalytic activity
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2006 nî lūn-bûn
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2006 թուականին հրատարակուած գիտական յօդուած
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2006 թվականին հրատարակված գիտական հոդված
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2006年の論文
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2006年論文
@yue
2006年論文
@zh-hant
2006年論文
@zh-hk
2006年論文
@zh-mo
2006年論文
@zh-tw
2006年论文
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name
The role of charged residues i ...... ression and catalytic activity
@ast
The role of charged residues i ...... ression and catalytic activity
@en
The role of charged residues i ...... ression and catalytic activity
@en-gb
The role of charged residues i ...... ression and catalytic activity
@nl
type
label
The role of charged residues i ...... ression and catalytic activity
@ast
The role of charged residues i ...... ression and catalytic activity
@en
The role of charged residues i ...... ression and catalytic activity
@en-gb
The role of charged residues i ...... ression and catalytic activity
@nl
prefLabel
The role of charged residues i ...... ression and catalytic activity
@ast
The role of charged residues i ...... ression and catalytic activity
@en
The role of charged residues i ...... ression and catalytic activity
@en-gb
The role of charged residues i ...... ression and catalytic activity
@nl
P2093
P2860
P3181
P1476
The role of charged residues i ...... ression and catalytic activity
@en
P2093
Christine Manoharan
Marieangela C Wilson
Richard B Sessions
P2860
P304
P3181
P356
10.1080/09687860600841967
P407
P577
2006-11-01T00:00:00Z