Unphosphorylated STAT1 prolongs the expression of interferon-induced immune regulatory genes.
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FER tyrosine kinase (FER) overexpression mediates resistance to quinacrine through EGF-dependent activation of NF-kappaBIFNβ-dependent increases in STAT1, STAT2, and IRF9 mediate resistance to viruses and DNA damageTranscriptional regulation by STAT1 and STAT2 in the interferon JAK-STAT pathwayInterferon Response in Hepatitis C Virus (HCV) Infection: Lessons from Cell Culture Systems of HCV InfectionProtein tyrosine phosphatases as wardens of STAT signalingInterferons as inducers of apoptosis in malignant cellsInducible, dose-adjustable and time-restricted reconstitution of STAT1 deficiency in vivoThe Ebola Virus Interferon Antagonist VP24 Directly Binds STAT1 and Has a Novel, Pyramidal FoldStructural and dynamic determinants of type I interferon receptor assembly and their functional interpretation.hCAF1/CNOT7 regulates interferon signalling by targeting STAT1.Interferon induction and function at the mucosal surface.Interferon regulatory factor-8 is important for histone deacetylase inhibitor-mediated antitumor activity.Structural and functional studies of STAT1 from Atlantic salmon (Salmo salar).High STAT1 mRNA levels but not its tyrosine phosphorylation are associated with macrophage infiltration and bad prognosis in breast cancer.Interferons and their stimulated genes in the tumor microenvironmentA novel mechanism of skin tumor promotion involving interferon-gamma (IFNγ)/signal transducer and activator of transcription-1 (Stat1) signaling.The cell-specific induction of CXC chemokine ligand 9 mediated by IFN-gamma in microglia of the central nervous system is determined by the myeloid transcription factor PU.1.Hepatitis C virus infection impairs IRF-7 translocation and Alpha interferon synthesis in immortalized human hepatocytesInterferon-stimulated genes: a complex web of host defenses.Camouflage and misdirection: the full-on assault of ebola virus diseaseSTAT1 regulates human glutaminase 1 promoter activity through multiple binding sites in HIV-1 infected macrophagesPulsed stable isotope labeling of amino acids in cell culture uncovers the dynamic interactions between HIV-1 and the monocyte-derived macrophage.Chromatin dynamics of gene activation and repression in response to interferon alpha (IFN(alpha)) reveal new roles for phosphorylated and unphosphorylated forms of the transcription factor STAT2Interferon-gamma-induced MD-2 protein expression and lipopolysaccharide (LPS) responsiveness in corneal epithelial cells is mediated by Janus tyrosine kinase-2 activation and direct binding of STAT1 protein to the MD-2 promoter.Targeting interferon response genes sensitizes aromatase inhibitor resistant breast cancer cells to estrogen-induced cell deathBeta interferon-mediated activation of signal transducer and activator of transcription protein 1 interferes with Rickettsia conorii replication in human endothelial cellsDysregulation of janus kinases and signal transducers and activators of transcription in cancer.Cell-type-specific type I interferon antagonism influences organ tropism of murine coronavirusStat1 stimulates cap-independent mRNA translation to inhibit cell proliferation and promote survival in response to antitumor drugsInhibitor of κB kinase epsilon (IKK(epsilon)), STAT1, and IFIT2 proteins define novel innate immune effector pathway against West Nile virus infectionEPSTI1 Is Involved in IL-28A-Mediated Inhibition of HCV InfectionDifferential cell autonomous responses determine the outcome of coxsackievirus infections in murine pancreatic α and β cellsVirus-activated interferon regulatory factor 7 upregulates expression of the interferon-regulated BST2 gene independently of interferon signalingFlavivirus Antagonism of Type I Interferon Signaling Reveals Prolidase as a Regulator of IFNAR1 Surface Expression.Interdependent and independent roles of type I interferons and IL-6 in innate immune, neuroinflammatory and sickness behaviour responses to systemic poly I:C.Interferon-γ biphasically regulates angiotensinogen expression via a JAK-STAT pathway and suppressor of cytokine signaling 1 (SOCS1) in renal proximal tubular cells.Regulation of karyopherin α1 and nuclear import by mammalian target of rapamycin.The conserved Cockayne syndrome B-piggyBac fusion protein (CSB-PGBD3) affects DNA repair and induces both interferon-like and innate antiviral responses in CSB-null cells.Roles of unphosphorylated ISGF3 in HCV infection and interferon responsiveness.A novel role for IFN-stimulated gene factor 3II in IFN-γ signaling and induction of antiviral activity in human cells.
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P2860
Unphosphorylated STAT1 prolongs the expression of interferon-induced immune regulatory genes.
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on 28 May 2009
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
@da
vědecký článek
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name
Unphosphorylated STAT1 prolong ...... duced immune regulatory genes.
@en
Unphosphorylated STAT1 prolong ...... duced immune regulatory genes.
@nl
type
label
Unphosphorylated STAT1 prolong ...... duced immune regulatory genes.
@en
Unphosphorylated STAT1 prolong ...... duced immune regulatory genes.
@nl
prefLabel
Unphosphorylated STAT1 prolong ...... duced immune regulatory genes.
@en
Unphosphorylated STAT1 prolong ...... duced immune regulatory genes.
@nl
P2860
P356
P1476
Unphosphorylated STAT1 prolong ...... duced immune regulatory genes.
@en
P2093
George R Stark
Hyeonjoo Cheon
P2860
P304
P356
10.1073/PNAS.0903487106
P407
P577
2009-05-28T00:00:00Z