Global analyses of UPF1 binding and function reveal expanded scope of nonsense-mediated mRNA decay.
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Nonsense-mediated mRNA decay: novel mechanistic insights and biological impactMechanism and regulation of the nonsense-mediated decay pathwayRetroviral strategy to stabilize viral RNAThe Clothes Make the mRNA: Past and Present Trends in mRNP FashionSelection for reduced translation costs at the intronic 5' end in fungiNonsense-mediated mRNA decay in humans at a glanceNonsense-Mediated mRNA Decay: Degradation of Defective Transcripts Is Only Part of the StoryOrganizing principles of mammalian nonsense-mediated mRNA decayEukaryotic initiation factor 4G suppresses nonsense-mediated mRNA decay by two genetically separable mechanismsHIV-1 Recruits UPF1 but Excludes UPF2 to Promote Nucleocytoplasmic Export of the Genomic RNA.Human Upf1 is a highly processive RNA helicase and translocase with RNP remodelling activitiesRNA sequencing of synaptic and cytoplasmic Upf1-bound transcripts supports contribution of nonsense-mediated decay to epileptogenesis.Modulation of nonsense mediated decay by rapamycinExperimental and Computational Considerations in the Study of RNA-Binding Protein-RNA InteractionsTranslation of small open reading frames within unannotated RNA transcripts in Saccharomyces cerevisiae.A post-translational regulatory switch on UPF1 controls targeted mRNA degradationHuman nonsense-mediated RNA decay initiates widely by endonucleolysis and targets snoRNA host genes.Detained introns are a novel, widespread class of post-transcriptionally spliced introns.Identification of elements in human long 3' UTRs that inhibit nonsense-mediated decay.The unfolded protein response is shaped by the NMD pathwayNMD: At the crossroads between translation termination and ribosome recycling.Nonsense-mediated RNA decay--a switch and dial for regulating gene expressionA critical role of RBM8a in proliferation and differentiation of embryonic neural progenitors.Chromatoid Body Protein TDRD6 Supports Long 3' UTR Triggered Nonsense Mediated mRNA Decay.UPF2-Dependent Nonsense-Mediated mRNA Decay Pathway Is Essential for Spermatogenesis by Selectively Eliminating Longer 3'UTR Transcripts.The role of nucleotide composition in premature termination codon recognition.Identification of novel post-transcriptional features in olfactory receptor family mRNAs.A system for coordinated analysis of translational readthrough and nonsense-mediated mRNA decay.Identification of targets of tumor suppressor microRNA-34a using a reporter library systemTarget Discrimination in Nonsense-Mediated mRNA Decay Requires Upf1 ATPase ActivityRecent transcriptome-wide mapping of UPF1 binding sites reveals evidence for its recruitment to mRNA before translation.Polypyrimidine tract binding protein 1 protects mRNAs from recognition by the nonsense-mediated mRNA decay pathway.Human nonsense-mediated mRNA decay factor UPF2 interacts directly with eRF3 and the SURF complexUpstream ORFs are prevalent translational repressors in vertebrates.Viral Evasion and Manipulation of Host RNA Quality Control Pathways.ATP hydrolysis by UPF1 is required for efficient translation termination at premature stop codons.Transcriptome-wide identification of NMD-targeted human mRNAs reveals extensive redundancy between SMG6- and SMG7-mediated degradation pathways.In vivo determination of direct targets of the nonsense-mediated decay pathway in Drosophila.Rbfox2 controls autoregulation in RNA-binding protein networks.Regulation of natural mRNAs by the nonsense-mediated mRNA decay pathway.
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Global analyses of UPF1 binding and function reveal expanded scope of nonsense-mediated mRNA decay.
description
article científic
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article scientifique
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articolo scientifico
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artigo científico
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bilimsel makale
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scientific article published on 13 June 2013
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
Global analyses of UPF1 bindin ...... nonsense-mediated mRNA decay.
@en
Global analyses of UPF1 bindin ...... nonsense-mediated mRNA decay.
@nl
type
label
Global analyses of UPF1 bindin ...... nonsense-mediated mRNA decay.
@en
Global analyses of UPF1 bindin ...... nonsense-mediated mRNA decay.
@nl
prefLabel
Global analyses of UPF1 bindin ...... nonsense-mediated mRNA decay.
@en
Global analyses of UPF1 bindin ...... nonsense-mediated mRNA decay.
@nl
P2093
P2860
P356
P1433
P1476
Global analyses of UPF1 bindin ...... nonsense-mediated mRNA decay.
@en
P2093
Alex D Robertson
Christopher B Burge
Jessica A Hurt
P2860
P304
P356
10.1101/GR.157354.113
P577
2013-06-13T00:00:00Z