Adult stem cell maintenance and tissue regeneration in the ageing context: the role for A-type lamins as intrinsic modulators of ageing in adult stem cells and their niches. - Test2 - elhamkhani - TriplyDB

Adult stem cell maintenance and tissue regeneration in the ageing context: the role for A-type lamins as intrinsic modulators of ageing in adult stem cells and their niches.

Adult stem cell maintenance and tissue regeneration in the ageing context: the role for A-type lamins as intrinsic modulators of ageing in adult stem cells and their niches.

http://www.wikidata.org/entity/Q37220177

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Lamin A/C haploinsufficiency modulates the differentiation potential of mouse embryonic stem cells Ultraviolet Radiation-Induced Skin Aging: The Role of DNA Damage and Oxidative Stress in Epidermal Stem Cell Damage Mediated Skin Aging Molecular mechanism of extrinsic factors affecting anti-aging of stem cells Suppression of lamin A/C by short hairpin RNAs promotes adipocyte lineage commitment in mesenchymal progenitor cell line, ROB-C26 Bone development Cancer biomarker discovery: the entropic hallmark.Prelamin A accumulation and stress conditions induce impaired Oct-1 activity and autophagy in prematurely aged human mesenchymal stem cell Comparative transcriptional profiling of the limbal epithelial crypt demonstrates its putative stem cell niche characteristics.Decreased bone formation and osteopenia in lamin a/c-deficient mice Conserved cysteine residues in the mammalian lamin A tail are essential for cellular responses to ROS generation.Energetics, epigenetics, mitochondrial genetics.Lamins at a glance.Bmi-1: At the crossroads of physiological and pathological biology.Influences of lamin A levels on induction of pluripotent stem cells.Skeletal muscle contractile function and neuromuscular performance in Zmpste24 -/- mice, a murine model of human progeria.Role of the nuclear envelope in the pathogenesis of age-related bone loss and osteoporosis.Stress and stem cells.Circulation autoantibody against Lamin A/C in patients with Sjögren's syndrome.Adult Stem Cells and Diseases of Aging.Nuclear damages and oxidative stress: new perspectives for laminopathies.Advances in basic and clinical research in laminopathies.What the genetics of lipodystrophy can teach us about insulin resistance and diabetes.Melatonin and the theories of aging: a critical appraisal of melatonin's role in antiaging mechanisms.Lamina-associated polypeptide (LAP)2α and nucleoplasmic lamins in adult stem cell regulation and disease.Nuclear Mechanics and Stem Cell Differentiation.Hutchinson-Gilford progeria syndrome as a model for vascular aging.Modelling the molecular mechanisms of aging.Elements of the niche for adult stem cell expansion.Engrafted peripheral blood-derived mesenchymal stem cells promote locomotive recovery in adult rats after spinal cord injury.Extracellular matrix-mediated differentiation of periodontal progenitor cells.Bradykinin regulates cell growth and migration in cultured human cardiac c-Kit+ progenitor cells LMNA variants cause cytoplasmic distribution of nuclear pore proteins in Drosophila and human muscle.No evidence for neo-oogenesis may link to ovarian senescence in adult monkey.The Potential of iPSCs for the Treatment of Premature Aging Disorders.Lamins and bone disorders: current understanding and perspectives.

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Adult stem cell maintenance and tissue regeneration in the ageing context: the role for A-type lamins as intrinsic modulators of ageing in adult stem cells and their niches.

http://www.wikidata.org/entity/Q37220177

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J.1469-7580.2008.00928.X

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Christopher J Hutchison

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Mutations in the gene encoding lamin A/C cause autosomal dominant Emery-Dreifuss muscular dystrophy

Alteration of nuclear lamin organization inhibits RNA polymerase II-dependent transcription

Patients with familial partial lipodystrophy of the Dunnigan type due to a LMNA R482W mutation show muscular and cardiac abnormalities

A novel role for the nuclear membrane protein emerin in association of the centrosome to the outer nuclear membrane

Nesprin-2 is a multi-isomeric protein that binds lamin and emerin at the nuclear envelope and forms a subcellular network in skeletal muscle

The inner nuclear membrane protein emerin regulates beta-catenin activity by restricting its accumulation in the nucleus

Nesprin-1alpha self-associates and binds directly to emerin and lamin A in vitro

Identification of a novel X-linked gene responsible for Emery-Dreifuss muscular dystrophy

Oncogenic ras provokes premature cell senescence associated with accumulation of p53 and p16INK4a

The integral inner nuclear membrane protein MAN1 physically interacts with the R-Smad proteins to repress signaling by the transforming growth factor-{beta} superfamily of cytokines

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10.1111/J.1469-7580.2008.00928.X

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Vanja Pekovic-Vaughan

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