The integral inner nuclear membrane protein MAN1 physically interacts with the R-Smad proteins to repress signaling by the transforming growth factor-{beta} superfamily of cytokines
about
The inner nuclear membrane protein emerin regulates beta-catenin activity by restricting its accumulation in the nucleus3-Phosphoinositide-dependent PDK1 negatively regulates transforming growth factor-beta-induced signaling in a kinase-dependent manner through physical interaction with Smad proteinsOverlapping functions of nuclear envelope proteins NET25 (Lem2) and emerin in regulation of extracellular signal-regulated kinase signaling in myoblast differentiationBMP2 and mechanical loading cooperatively regulate immediate early signalling events in the BMP pathwayIdentification of novel Smad2 and Smad3 associated proteins in response to TGF-beta1TMEM120A and B: Nuclear Envelope Transmembrane Proteins Important for Adipocyte DifferentiationAnchoring a Leviathan: How the Nuclear Membrane Tethers the GenomeThe nuclear envelope as a chromatin organizerLamina-associated polypeptide (LAP)2α and other LEM proteins in cancer biologyAsi1 is an inner nuclear membrane protein that restricts promoter access of two latent transcription factors.Inner nuclear membrane proteins Asi1, Asi2, and Asi3 function in concert to maintain the latent properties of transcription factors Stp1 and Stp2.The endonuclease Ankle1 requires its LEM and GIY-YIG motifs for DNA cleavage in vivoThe nuclear envelope at a glanceNuclear envelope protein Lem2 is required for mouse development and regulates MAP and AKT kinasesNET37, a nuclear envelope transmembrane protein with glycosidase homology, is involved in myoblast differentiationNuclear envelope transmembrane proteins (NETs) that are up-regulated during myogenesis.Diseases of the nuclear envelope.Genome-wide analysis links emerin to neuromuscular junction activity in Caenorhabditis elegans.Lamin-binding ProteinsA flow cytometry-based screen of nuclear envelope transmembrane proteins identifies NET4/Tmem53 as involved in stress-dependent cell cycle withdrawal.Decreased bone formation and osteopenia in lamin a/c-deficient miceThe self-limiting dynamics of TGF-β signaling in silico and in vitro, with negative feedback through PPM1A upregulation.Nuclear envelope protein MAN1 regulates clock through BMAL1"Laminopathies": a wide spectrum of human diseases.Inner nuclear membrane proteins: impact on human disease.Lmo7 is an emerin-binding protein that regulates the transcription of emerin and many other muscle-relevant genes.Cellular mechanosensing: getting to the nucleus of it all.Structural protein 4.1R is integrally involved in nuclear envelope protein localization, centrosome-nucleus association and transcriptional signaling.Ubiquitin ligase Nedd4L targets activated Smad2/3 to limit TGF-beta signaling.A FoxO-Smad synexpression group in human keratinocytesTGFβ superfamily signaling regulators are differentially expressed in the developing and adult mouse testis.Nuclear membrane diversity: underlying tissue-specific pathologies in disease?The cellular mastermind(?)-mechanotransduction and the nucleus.Guilt by association: the nuclear envelope proteome and disease.What MAN1 does to the Smads. TGFbeta/BMP signaling and the nuclear envelope.Gene silencing at the nuclear periphery.Dependence of diffusional mobility of integral inner nuclear membrane proteins on A-type lamins.Tissue-specific defects are caused by loss of the Drosophila MAN1 LEM domain protein.The inner nuclear envelope as a transcription factor resting place.Till disassembly do us part: a happy marriage of nuclear envelope and chromatin.
P2860
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P248
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P2860
The integral inner nuclear membrane protein MAN1 physically interacts with the R-Smad proteins to repress signaling by the transforming growth factor-{beta} superfamily of cytokines
description
2005 nî lūn-bûn
@nan
2005 թուականի Ապրիլին հրատարակուած գիտական յօդուած
@hyw
2005 թվականի ապրիլին հրատարակված գիտական հոդված
@hy
2005年の論文
@ja
2005年論文
@yue
2005年論文
@zh-hant
2005年論文
@zh-hk
2005年論文
@zh-mo
2005年論文
@zh-tw
2005年论文
@wuu
name
The integral inner nuclear mem ...... beta} superfamily of cytokines
@ast
The integral inner nuclear mem ...... beta} superfamily of cytokines
@en
The integral inner nuclear mem ...... beta} superfamily of cytokines
@en-gb
The integral inner nuclear mem ...... beta} superfamily of cytokines
@nl
type
label
The integral inner nuclear mem ...... beta} superfamily of cytokines
@ast
The integral inner nuclear mem ...... beta} superfamily of cytokines
@en
The integral inner nuclear mem ...... beta} superfamily of cytokines
@en-gb
The integral inner nuclear mem ...... beta} superfamily of cytokines
@nl
prefLabel
The integral inner nuclear mem ...... beta} superfamily of cytokines
@ast
The integral inner nuclear mem ...... beta} superfamily of cytokines
@en
The integral inner nuclear mem ...... beta} superfamily of cytokines
@en-gb
The integral inner nuclear mem ...... beta} superfamily of cytokines
@nl
P2093
P2860
P921
P3181
P356
P1476
The integral inner nuclear mem ...... beta} superfamily of cytokines
@en
P2093
Kunxin Luo
Luis D Estévez-Salmerón
Shannon L Stroschein
Sharleen Zhou
Xueliang Zhu
P2860
P304
15992-6001
P3181
P356
10.1074/JBC.M411234200
P407
P577
2005-04-22T00:00:00Z