Initiation of immune tolerance-controlled HIV gp41 neutralizing B cell lineages
about
Humanized Immunoglobulin Mice: Models for HIV Vaccine Testing and Studying the Broadly Neutralizing Antibody Problem.Vaccine Elicitation of High Mannose-Dependent Neutralizing Antibodies against the V3-Glycan Broadly Neutralizing Epitope in Nonhuman PrimatesAntiretroviral naive and treated patients: Discrepancies of B cell subsets during the natural course of human immunodeficiency virus type 1 infectionAmino Acid Changes in the HIV-1 gp41 Membrane Proximal Region Control Virus Neutralization Sensitivity.Progress toward active or passive HIV-1 vaccination.Breaching peripheral tolerance promotes the production of HIV-1-neutralizing antibodies.Germline-targeting immunogens.Approaches to the induction of HIV broadly neutralizing antibodies.Genetic and structural analyses of affinity maturation in the humoral response to HIV-1.Human Ig knockin mice to study the development and regulation of HIV-1 broadly neutralizing antibodies.Antibody-virus co-evolution in HIV infection: paths for HIV vaccine development.Host controls of HIV broadly neutralizing antibody development.Immunological tolerance as a barrier to protective HIV humoral immunity.Development of a recombinant yellow fever vector expressing a HIV clade C founder envelope gp120.Potent and broad HIV-neutralizing antibodies in memory B cells and plasma.Immune perturbations in HIV-1-infected individuals who make broadly neutralizing antibodies.What Are the Primary Limitations in B-Cell Affinity Maturation, and How Much Affinity Maturation Can We Drive with Vaccination? Breaking through Immunity's Glass Ceiling.A heterologous prime-boosting strategy with replicating Vaccinia virus vectors and plant-produced HIV-1 Gag/dgp41 virus-like particles.HIV-1 Envelope Mimicry of Host Enzyme Kynureninase Does Not Disrupt Tryptophan Metabolism.Human Immunodeficiency Virus Proteins Mimic Human T Cell Receptors Inducing Cross-Reactive Antibodies.Immunologic Insights on the Membrane Proximal External Region: A Major Human Immunodeficiency Virus Type-1 Vaccine Target.Initiation of HIV neutralizing B cell lineages with sequential envelope immunizations.Optimization of the EC26-2A4 epitope in the gp41 membrane proximal external region (MPER) targeted by neutralizing antibodies from an elite controller.The development of HIV vaccines targeting gp41 membrane-proximal external region (MPER): challenges and prospects.Anti-HIV-1 B cell responses are dependent on B cell precursor frequency and antigen-binding affinity.Conformational Plasticity in Broadly Neutralizing HIV-1 Antibodies Triggers Polyreactivity.Functional Relevance of Improbable Antibody Mutations for HIV Broadly Neutralizing Antibody Development.
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Initiation of immune tolerance-controlled HIV gp41 neutralizing B cell lineages
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article científic
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article scientifique
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articolo scientifico
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artigo científico
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bilimsel makale
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scientific article published on April 2016
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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Initiation of immune tolerance-controlled HIV gp41 neutralizing B cell lineages
@en
Initiation of immune tolerance-controlled HIV gp41 neutralizing B cell lineages.
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label
Initiation of immune tolerance-controlled HIV gp41 neutralizing B cell lineages
@en
Initiation of immune tolerance-controlled HIV gp41 neutralizing B cell lineages.
@nl
prefLabel
Initiation of immune tolerance-controlled HIV gp41 neutralizing B cell lineages
@en
Initiation of immune tolerance-controlled HIV gp41 neutralizing B cell lineages.
@nl
P2093
P2860
P50
P1476
Initiation of immune tolerance-controlled HIV gp41 neutralizing B cell lineages
@en
P2093
Andrew Foulger
Ashley M Trama
Charles W Pemble
Georgia D Tomaras
Hilary Bouton-Verville
Hua-Xin Liao
Jessica N Peel
Jinsong Zhang
P2860
P304
P356
10.1126/SCITRANSLMED.AAF0618
P407
P577
2016-04-01T00:00:00Z