about
Reducing V3 Antigenicity and Immunogenicity on Soluble, Native-Like HIV-1 Env SOSIP TrimersImproving the Expression and Purification of Soluble, Recombinant Native-Like HIV-1 Envelope Glycoprotein Trimers by Targeted Sequence Changes.The quest for an antibody-based HIV vaccine.Design and crystal structure of a native-like HIV-1 envelope trimer that engages multiple broadly neutralizing antibody precursors in vivo.Functional Stability of HIV-1 Envelope Trimer Affects Accessibility to Broadly Neutralizing Antibodies at its Apex.cGMP production and analysis of BG505 SOSIP.664, an extensively glycosylated, trimeric HIV-1 envelope glycoprotein vaccine candidate.Phenotypic deficits in the HIV-1 envelope are associated with the maturation of a V2-directed broadly neutralizing antibody lineage.Epitopes for neutralizing antibodies induced by HIV-1 envelope glycoprotein BG505 SOSIP trimers in rabbits and macaques.Co-evolution of HIV Envelope and Apex-Targeting Neutralizing Antibody Lineage Provides Benchmarks for Vaccine Design.Site-Specific Glycosylation of Virion-Derived HIV-1 Env Is Mimicked by a Soluble Trimeric ImmunogenThe human naive B cell repertoire contains distinct subclasses for a germline-targeting HIV-1 vaccine immunogenThe role of follicular helper CD4 T cells in the development of HIV-1 specific broadly neutralizing antibody responsesWhen designing vaccines, consider the starting material: the human B cell repertoire
P2860
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P2860
description
2017 nî lūn-bûn
@nan
2017年の論文
@ja
2017年論文
@yue
2017年論文
@zh-hant
2017年論文
@zh-hk
2017年論文
@zh-mo
2017年論文
@zh-tw
2017年论文
@wuu
2017年论文
@zh
2017年论文
@zh-cn
name
Germline-targeting immunogens.
@en
type
label
Germline-targeting immunogens.
@en
prefLabel
Germline-targeting immunogens.
@en
P2093
P2860
P356
P1476
Germline-targeting immunogens.
@en
P2093
Andrew T McGuire
Leonidas Stamatatos
Marie Pancera
P2860
P304
P356
10.1111/IMR.12483
P577
2017-01-01T00:00:00Z