p38 MAPK is a major regulator of MafA protein stability under oxidative stress.
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β-cell dedifferentiation in diabetes is important, but what is it?Differentiation of pancreatic endocrine progenitors reversibly blocked by premature induction of MafAHeterozygous SOD2 deletion impairs glucose-stimulated insulin secretion, but not insulin action, in high-fat-fed mice.Regulation of the CCL2 gene in pancreatic β-cells by IL-1β and glucocorticoids: role of MKP-1.Mafa expression enhances glucose-responsive insulin secretion in neonatal rat beta cells.Mice lacking the p43 mitochondrial T3 receptor become glucose intolerant and insulin resistant during aging.Aldosterone induces clonal β-cell failure through glucocorticoid receptor.Islet β cell mass in diabetes and how it relates to function, birth, and death.Thyroid hormone promotes postnatal rat pancreatic β-cell development and glucose-responsive insulin secretion through MAFA.Preventing p38 MAPK-mediated MafA degradation ameliorates β-cell dysfunction under oxidative stress.Inactivation of specific β cell transcription factors in type 2 diabetes.The Role of Oxidative Stress and Hypoxia in Pancreatic Beta-Cell Dysfunction in Diabetes Mellitus.MafA and MafB activity in pancreatic β cells.Proper activation of MafA is required for optimal differentiation and maturation of pancreatic β-cellsShielding Engineered Islets With Mesenchymal Stem Cells Enhance Survival Under Hypoxia.The undoing and redoing of the diabetic β-cell.Distinct Shift in Beta-Cell Glutaredoxin 5 Expression Is Mediated by Hypoxia and Lipotoxicity Both In Vivo and In Vitro.MAFb protein confers intrinsic resistance to proteasome inhibitors in multiple myeloma.Reversal of angiotensin ll-induced β-cell dedifferentiation via inhibition of NF-κb signaling
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p38 MAPK is a major regulator of MafA protein stability under oxidative stress.
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on 30 April 2009
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
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vědecký článek
@cs
name
p38 MAPK is a major regulator of MafA protein stability under oxidative stress.
@en
p38 MAPK is a major regulator of MafA protein stability under oxidative stress.
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type
label
p38 MAPK is a major regulator of MafA protein stability under oxidative stress.
@en
p38 MAPK is a major regulator of MafA protein stability under oxidative stress.
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prefLabel
p38 MAPK is a major regulator of MafA protein stability under oxidative stress.
@en
p38 MAPK is a major regulator of MafA protein stability under oxidative stress.
@nl
P2093
P2860
P356
P1476
p38 MAPK is a major regulator of MafA protein stability under oxidative stress.
@en
P2093
Arun Sharma
D Ross Laybutt
George King
Gordon Weir
Ilham El Khattabi
Pedro Geraldes
Samit Shah
Takuma Kondo
P2860
P304
P356
10.1210/ME.2008-0482
P577
2009-04-30T00:00:00Z