Mafa expression enhances glucose-responsive insulin secretion in neonatal rat beta cells. - Test2 - elhamkhani - TriplyDB

Mafa expression enhances glucose-responsive insulin secretion in neonatal rat beta cells.

Mafa expression enhances glucose-responsive insulin secretion in neonatal rat beta cells.

http://www.wikidata.org/entity/Q34617916

about

Using Drosophila to discover mechanisms underlying type 2 diabetes Regenerative Therapy of Type 1 Diabetes Mellitus: From Pancreatic Islet Transplantation to Mesenchymal Stem Cells β-cell dedifferentiation in diabetes is important, but what is it?Reversal of hyperglycemia by insulin-secreting rat bone marrow- and blastocyst-derived hypoblast stem cell-like cells Current status of regeneration of pancreatic β-cells Pax6 is crucial for β-cell function, insulin biosynthesis, and glucose-induced insulin secretion The MafA transcription factor becomes essential to islet β-cells soon after birth.Rat neonatal beta cells lack the specialised metabolic phenotype of mature beta cells.Human pluripotent stem cell differentiation to functional pancreatic cells for diabetes therapies: Innovations, challenges and future directions.Differentiation of pancreatic endocrine progenitors reversibly blocked by premature induction of MafA Development of the endocrine pancreas and novel strategies for β-cell mass restoration and diabetes therapy.Maturation of stem cell-derived beta-cells guided by the expression of urocortin 3.Mice lacking the p43 mitochondrial T3 receptor become glucose intolerant and insulin resistant during aging.The Possible Mechanisms of the Impaired Insulin Secretion in Hypothyroid Rats.β-Cell-Specific Mafk Overexpression Impairs Pancreatic Endocrine Cell Development.Deconstructing pancreas developmental biology.Postnatal β-cell maturation is associated with islet-specific microRNA changes induced by nutrient shifts at weaning.Inhibition of Small Maf Function in Pancreatic β-Cells Improves Glucose Tolerance Through the Enhancement of Insulin Gene Transcription and Insulin Secretion.MAFA and T3 Drive Maturation of Both Fetal Human Islets and Insulin-Producing Cells Differentiated From hESC MLL3 and MLL4 Methyltransferases Bind to the MAFA and MAFB Transcription Factors to Regulate Islet β-Cell Function.The Chromatin Modifier MSK1/2 Suppresses Endocrine Cell Fates during Mouse Pancreatic Development.Subpopulations of GFP-marked mouse pancreatic β-cells differ in size, granularity, and insulin secretion.The MAFB transcription factor impacts islet α-cell function in rodents and represents a unique signature of primate islet β-cells.Neonatal β cell development in mice and humans is regulated by calcineurin/NFAT Thyroid hormone promotes postnatal rat pancreatic β-cell development and glucose-responsive insulin secretion through MAFA.Age-Dependent Pancreatic Gene Regulation Reveals Mechanisms Governing Human β Cell Function.Dynamic development of the pancreas from birth to adulthood.Preventing p38 MAPK-mediated MafA degradation ameliorates β-cell dysfunction under oxidative stress.PDX1 in ducts is not required for postnatal formation of β-cells but is necessary for their subsequent maturation.Differentiated human stem cells resemble fetal, not adult, β cells.The Diabetes-Linked Transcription Factor PAX4: From Gene to Functional Consequences.PAX4 promotes PDX1-induced differentiation of mesenchymal stem cells into insulin-secreting cells MafA and MafB activity in pancreatic β cells.Proper activation of MafA is required for optimal differentiation and maturation of pancreatic β-cells Dityrosine administration induces dysfunction of insulin secretion accompanied by diminished thyroid hormones T3 function in pancreas of mice.Pseudotemporal Ordering of Single Cells Reveals Metabolic Control of Postnatal β Cell Proliferation.Maturation and function of human embryonic stem cell-derived pancreatic progenitors in macroencapsulation devices following transplant into mice.All mixed up: defining roles for β-cell subtypes in mature islets.V-Maf Musculoaponeurotic Fibrosarcoma Oncogene Homolog A Synthetic Modified mRNA Drives Reprogramming of Human Pancreatic Duct-Derived Cells Into Insulin-Secreting Cells How stable is repression of disallowed genes in pancreatic islets in response to metabolic stress?

P2860

Q26751078-97889384-5729-4799-8125-D251C5143724 Q26752205-9C822E91-0467-4CAF-92B7-AC81B9DEDDA3 Q27011272-E7647A3E-D176-4758-9E70-85047E7E67D0 Q27320637-4CDD6194-394B-4679-88DE-535B2024A944 Q28240432-703531E5-02AD-416D-A14A-F56CC32FE9A6 Q28572440-4C407BBE-2350-4E16-9BF7-7DDCAF0BC257 Q33646781-87D291BA-39BE-4675-A4CE-A5B0F9E7BC71 Q33794947-B1261005-B296-4E94-8E8A-59A28884AB0D Q33864580-161B53F9-0E5A-45E5-9990-C3E53CB7064C Q34382056-EA7F1731-8F5E-44C8-B2DE-9D1681933E5F Q34485165-AB8516D7-E5FA-42FC-B6E4-A2F1F9EF798A Q34972402-02114FFE-0EEE-48F1-BD74-5359537799FB Q35009942-EBBD8CC1-8060-4876-B9A6-6384A4B00395 Q35680164-E7B898F6-FB62-424C-9C3A-201C614BAAB9 Q35930727-9573AEAB-DD9E-4408-9CE4-52129E7E9CF5 Q36009271-B0C55835-133D-4D2E-89D3-ACFD9C1040CC Q36059303-FB5A0ED7-8E29-44D1-BF24-E598CACE9F04 Q36107478-E43CCBA7-543A-414A-84AE-F626412847F3 Q36129815-DDC7FBF0-4579-4BBB-91C9-F2056B7C5300 Q36186295-F84C4040-F11E-46B7-9A9A-2A6174AA01BE Q36223618-A1F6AED7-721D-4004-A422-5F3E9913E7C3 Q36323202-B7AE8A88-8305-4C77-8F01-7147716E42DD Q36363326-3CAFF1BE-58E2-4AE3-89E4-DCB3AB23F390 Q36655088-ED745750-A400-438D-BCE8-535ED8BA57CA Q36796031-F6F95140-7CD4-4122-81A4-E68B063C1432 Q36892940-93676EC6-DFDA-4173-AF7E-ECDD511A5671 Q36986973-63E4D37B-7FC9-4132-B952-2F9D309C7A9A Q36998047-B9A25FA3-4944-485F-9D65-2439DDBE113F Q37193305-C8BAA2B5-CD9E-4CCD-9583-720DD8B6DB14 Q37612773-D858DDA7-FFAD-4B58-901E-2F61991DDFF5 Q37724128-BEC8392A-3BDC-41E7-992E-1C2992D5F8C2 Q37732934-BB9E7663-0B89-432B-B0E2-A678AC78C704 Q37896334-4994EF29-9641-4A93-9B16-E0CB679A3B7B Q38676902-AB0E7232-0C26-4CFD-A85C-65B795A2F2B1 Q38720814-7DE9FDB3-A0D9-4393-83C9-FC1F7C9CA93F Q38806833-89B5B679-9E35-4769-A114-6CE86500FBDE Q39138981-798821B0-4369-4EFD-998E-EBF4A3C4EA04 Q39167044-35C9E86D-994F-4069-B661-3358F15393E4 Q39609204-D2B53B89-CB18-4FD6-B02D-D30190AD4E4A Q41326000-097CF602-3BF1-432A-A6A3-4AC4C96BF667

P2860

Mafa expression enhances glucose-responsive insulin secretion in neonatal rat beta cells.

http://www.wikidata.org/entity/Q34617916

description

2010 nî lūn-bûn

@nan

2010 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած

@hyw

2010 թվականի դեկտեմբերին հրատարակված գիտական հոդված

@hy

2010年の論文

@ja

2010年論文

@yue

2010年論文

@zh-hant

2010年論文

@zh-hk

2010年論文

@zh-mo

2010年論文

@zh-tw

2010年论文

@wuu

name

Mafa expression enhances glucose-responsive insulin secretion in neonatal rat beta cells.

@ast

Mafa expression enhances glucose-responsive insulin secretion in neonatal rat beta cells.

@en

Mafa expression enhances glucose-responsive insulin secretion in neonatal rat beta cells.

@nl

type

label

Mafa expression enhances glucose-responsive insulin secretion in neonatal rat beta cells.

@ast

Mafa expression enhances glucose-responsive insulin secretion in neonatal rat beta cells.

@en

Mafa expression enhances glucose-responsive insulin secretion in neonatal rat beta cells.

@nl

prefLabel

Mafa expression enhances glucose-responsive insulin secretion in neonatal rat beta cells.

@ast

Mafa expression enhances glucose-responsive insulin secretion in neonatal rat beta cells.

@en

Mafa expression enhances glucose-responsive insulin secretion in neonatal rat beta cells.

@nl

P1433

Q34617916-E06B22A2-8D80-4808-B628-A0B1D225850F

P1476

Q34617916-4005102B-C9EE-4E25-8F0E-0A73890BF070

P2093

Q34617916-0788DAC5-2642-4DB2-9E2F-8E45F81C3DD6

Q34617916-15A78F5F-1F12-473F-BC6F-06A94EC4D35F

Q34617916-33E650A8-E8D4-4B85-861C-8B53A184DD16

Q34617916-3437A69E-EAB6-41E8-B496-DD07B047C0E7

Q34617916-602D2183-C24C-4B6F-BB50-A56EA3643FBD

Q34617916-913BBF22-FA05-4CC5-BD3E-CAA21D7D4E82

Q34617916-95EDCC17-C386-4A32-AC1B-83FE84303C11

Q34617916-C979BC14-B77D-4FA5-9883-76CE52841C07

Q34617916-D608D677-63BC-46CC-AB2A-BF260B9ADA08

Q34617916-F6926ADE-E86D-4130-BE5E-4B1FD4B1B2EE

P2860

Q34617916-007E68DE-BE9F-4D69-9E65-373EA0AC0A71

Q34617916-054F9B6B-5683-4FF2-A5B5-37661616A0EE

Q34617916-10B9BA54-4E88-4554-8EA4-D0E58593E8CF

Q34617916-1224754D-E6D2-4C96-AB3F-56F5CFB23E5C

Q34617916-12B82B69-F472-4DFE-BC4D-71063235FA2C

Q34617916-183872B7-32E8-4D6E-A32E-66DD2617C15E

Q34617916-1C725660-6C48-4920-BA78-F407E7F44C6C

Q34617916-1ECDD24E-07D4-4373-A45D-9A178FB9AF6A

Q34617916-1F4F7DFD-2D67-4DDC-8733-F09DB8F46A37

Q34617916-28DD9A16-E4C9-4B64-824D-8E697273B7EB

P2888

Q34617916-B0AD3D21-C60B-42C5-A2B6-387CE9272587

P304

Q34617916-2083DD1E-A6E1-4565-9F57-713BE8A92411

P31

Q34617916-1072C73B-3D0D-4C15-9C30-DE3EFC26629C

P356

Q34617916-C580B32C-1B07-4862-8716-F96718EAF000

P433

Q34617916-CDF94390-935A-4EAB-9659-03E5F264B14F

P478

Q34617916-457A408D-7F08-4352-BAD6-6894E7810F27

P577

Q34617916-9C1F3576-A2A2-4577-8367-38974765DAA9

P5875

Q34617916-DE296ADB-1565-499E-BB9B-F0ECEBE7BA3D

P6179

Q34617916-23282E4F-29E5-464E-9C6D-1045E25D7B7B

P698

Q34617916-64571985-6F96-430B-8C7D-06C25AA18D3B

P921

Q34617916-3AD8800D-990D-49EC-84D6-C9175ED575F8

P932

Q34617916-3431C0AA-CCAA-456A-B9C8-A42A06184D1E

P356

S00125-010-2026-Z

P1433

P1476

Mafa expression enhances glucose-responsive insulin secretion in neonatal rat beta cells.

@en

P2093

A Jermendy

http://www.w3.org/2001/XMLSchema#string

A Koh

http://www.w3.org/2001/XMLSchema#string

A Sharma

http://www.w3.org/2001/XMLSchema#string

C Aguayo-Mazzucato

http://www.w3.org/2001/XMLSchema#string

E Toschi

http://www.w3.org/2001/XMLSchema#string

G C Weir

http://www.w3.org/2001/XMLSchema#string

I El Khattabi

http://www.w3.org/2001/XMLSchema#string

K Juhl

http://www.w3.org/2001/XMLSchema#string

K Mao

http://www.w3.org/2001/XMLSchema#string

S Bonner-Weir

http://www.w3.org/2001/XMLSchema#string

P2860

MafB is required for islet beta cell maturation

FoxA2, Nkx2.2, and PDX-1 regulate islet beta-cell-specific mafA expression through conserved sequences located between base pairs -8118 and -7750 upstream from the transcription start site

In vivo reprogramming of adult pancreatic exocrine cells to beta-cells

Role of NADH shuttles in glucose-induced insulin secretion from fetal beta-cells

Pancreatic endoderm derived from human embryonic stem cells generates glucose-responsive insulin-secreting cells in vivo

Production of pancreatic hormone-expressing endocrine cells from human embryonic stem cells

PDX-1 is required for pancreatic outgrowth and differentiation of the rostral duodenum

Insulin-promoter-factor 1 is required for pancreas development in mice

Restructuring of pancreatic islets and insulin secretion in a postnatal critical window.

Rat neonatal beta cells lack the specialised metabolic phenotype of mature beta cells.

P2888

s00125-010-2026-z

P304

583-593

http://www.w3.org/2001/XMLSchema#string

P31

scholarly article

P356

10.1007/S00125-010-2026-Z

http://www.w3.org/2001/XMLSchema#string

P433

3

http://www.w3.org/2001/XMLSchema#string

P478

54

http://www.w3.org/2001/XMLSchema#string

P577

2010-12-29T00:00:00Z

http://www.w3.org/2001/XMLSchema#dateTime

P5875

49713374

http://www.w3.org/2001/XMLSchema#string

P6179

1050066526

http://www.w3.org/2001/XMLSchema#string

P698

21190012

http://www.w3.org/2001/XMLSchema#string

P921

P932

3047400

http://www.w3.org/2001/XMLSchema#string