Tryptophan cluster protects human γD-crystallin from ultraviolet radiation-induced photoaggregation in vitro.
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UV-B induced fibrillization of crystallin protein mixturesAcetylation of Gly1 and Lys2 promotes aggregation of human γD-crystallin.Wild-type human γD-crystallin promotes aggregation of its oxidation-mimicking, misfolding-prone W42Q mutant.The βγ-crystallins: native state stability and pathways to aggregation.Tyrosine/cysteine cluster sensitizing human γD-crystallin to ultraviolet radiation-induced photoaggregation in vitro.An Internal Disulfide Locks a Misfolded Aggregation-prone Intermediate in Cataract-linked Mutants of Human γD-Crystallin.An alternative structural isoform in amyloid-like aggregates formed from thermally denatured human γD-crystallin.Aggregation of Trp > Glu point mutants of human gamma-D crystallin provides a model for hereditary or UV-induced cataract.Protection of human γB-crystallin from UV-induced damage by epigallocatechin gallate: spectroscopic and docking studies.Amyloid β-Sheet Secondary Structure Identified in UV-Induced Cataracts of Porcine Lenses using 2D IR Spectroscopy.Rosmarinic Acid Restores Complete Transparency of Sonicated Human Cataract Ex Vivo and Delays Cataract Formation In Vivo.Dynamic disulfide exchange in a crystallin protein in the human eye lens promotes cataract-associated aggregation
P2860
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P2860
Tryptophan cluster protects human γD-crystallin from ultraviolet radiation-induced photoaggregation in vitro.
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article científic
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article scientifique
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articolo scientifico
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artigo científico
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bilimsel makale
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scientific article published on 20 June 2013
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
Tryptophan cluster protects hu ...... ced photoaggregation in vitro.
@en
Tryptophan cluster protects hu ...... ced photoaggregation in vitro.
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type
label
Tryptophan cluster protects hu ...... ced photoaggregation in vitro.
@en
Tryptophan cluster protects hu ...... ced photoaggregation in vitro.
@nl
prefLabel
Tryptophan cluster protects hu ...... ced photoaggregation in vitro.
@en
Tryptophan cluster protects hu ...... ced photoaggregation in vitro.
@nl
P2860
P356
P1476
Tryptophan cluster protects hu ...... ced photoaggregation in vitro.
@en
P2093
Jonathan King
Nathaniel Schafheimer
P2860
P304
P356
10.1111/PHP.12096
P577
2013-06-20T00:00:00Z