The Human W42R  D-Crystallin Mutant Structure Provides a Link between Congenital and Age-related Cataracts

The Human W42R  D-Crystallin Mutant Structure Provides a Link between Congenital and Age-related Cataracts

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http://www.wikidata.org/entity/Q27674968
Crystal structure of the cataract-causing P23T γD-crystallin mutantSolution NMR Structures of Pyrenophora tritici-repentis ToxB and Its Inactive Homolog Reveal Potential Determinants of Toxin ActivityFunctions of crystallins in and out of lens: roles in elongated and post-mitotic cellsLens β-crystallins: the role of deamidation and related modifications in aging and cataract.Cataract-associated P23T γD-crystallin retains a native-like fold in amorphous-looking aggregates formed at physiological pH.Biophysics of protein evolution and evolutionary protein biophysicsRNA granule component TDRD7 gene polymorphisms in a Han Chinese population with age-related cataract.Structural integrity of the Greek key motif in βγ-crystallins is vital for central eye lens transparencyWild-type human γD-crystallin promotes aggregation of its oxidation-mimicking, misfolding-prone W42Q mutant.The βγ-crystallins: native state stability and pathways to aggregation.Tryptophan cluster protects human γD-crystallin from ultraviolet radiation-induced photoaggregation in vitro.A Combined NMR and SAXS Analysis of the Partially Folded Cataract-Associated V75D γD-Crystallin.An Internal Disulfide Locks a Misfolded Aggregation-prone Intermediate in Cataract-linked Mutants of Human γD-Crystallin.Aggregation of Trp > Glu point mutants of human gamma-D crystallin provides a model for hereditary or UV-induced cataract.Dynamic disulfide exchange in a crystallin protein in the human eye lens promotes cataract-associated aggregation
P2860

The Human W42R  D-Crystallin Mutant Structure Provides a Link between Congenital and Age-related Cataracts

Item
http://www.wikidata.org/entity/Q27674968
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2013 nî lūn-bûn
@nan
2013 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
2013 թվականի հունվարին հրատարակված գիտական հոդված
@hy
2013年の論文
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2013年論文
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2013年論文
@zh-hant
2013年論文
@zh-hk
2013年論文
@zh-mo
2013年論文
@zh-tw
2013年论文
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name
The Human W42R  D-Crystallin M ...... ital and Age-related Cataracts
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The Human W42R  D-Crystallin M ...... ital and Age-related Cataracts
@en
The Human W42R  D-Crystallin M ...... ital and Age-related Cataracts
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type
label
The Human W42R  D-Crystallin M ...... ital and Age-related Cataracts
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The Human W42R  D-Crystallin M ...... ital and Age-related Cataracts
@en
The Human W42R  D-Crystallin M ...... ital and Age-related Cataracts
@nl
prefLabel
The Human W42R  D-Crystallin M ...... ital and Age-related Cataracts
@ast
The Human W42R  D-Crystallin M ...... ital and Age-related Cataracts
@en
The Human W42R  D-Crystallin M ...... ital and Age-related Cataracts
@nl
P1433
P1476
P2093
P2860
P304
P31
P356
P407
P433
P478
P50
P577
P698
P921
P932
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P1433
P1476
The Human W42R  D-Crystallin M ...... ital and Age-related Cataracts
@en
P2093
P2860
P304
P31
P356
P407
P433
P478
P50
P577
P698
P921
P932