Enzymatic mechanism of human apurinic/apyrimidinic endonuclease against a THF AP site model substrate.
about
Molecular mechanisms of the whole DNA repair system: a comparison of bacterial and eukaryotic systemsConserved Structural Chemistry for Incision Activity in Structurally Non-homologous Apurinic/Apyrimidinic Endonuclease APE1 and Endonuclease IV DNA Repair EnzymesEffects of mono- and divalent metal ions on DNA binding and catalysis of human apurinic/apyrimidinic endonuclease 1.Small molecule inhibitors of DNA repair nuclease activities of APE1.High-resolution crystal structures reveal plasticity in the metal binding site of apurinic/apyrimidinic endonuclease I.Design and activity of AP endonuclease-1 inhibitors.Capturing snapshots of APE1 processing DNA damage.Transient-state kinetics of apurinic/apyrimidinic (AP) endonuclease 1 acting on an authentic AP site and commonly used substrate analogs: the effect of diverse metal ions and base mismatches.Human apurinic/apyrimidinic endonuclease 1.Study of the Phosphoryl-Transfer Mechanism of Shikimate Kinase by NMR Spectroscopy.Assembly of the base excision repair complex on abasic DNA and role of adenomatous polyposis coli on its functional activity.Construction of a Full-Atomic Mechanistic Model of Human Apurinic/Apyrimidinic Endonuclease APE1 for Virtual Screening of Novel Inhibitors.Conformational transitions in human AP endonuclease 1 and its active site mutant during abasic site repair.Molecular snapshots of APE1 proofreading mismatches and removing DNA damage.Chinese hamster AP endonuclease operates by a two-metal ion assisted catalytic mechanism.Kinetic Features of 3'-5' Exonuclease Activity of Human AP-Endonuclease APE1
P2860
Q24630140-44E2EC0C-9FB1-4C61-8267-8597A2C56909Q27676022-62EDBADD-004E-46B7-B925-398B05532B43Q30386684-17B01852-6FAC-457B-94AA-F57D6FE18F2FQ34208966-1B5C8BEF-42BC-4927-B107-B228AD208E53Q34379637-AF3033EA-33E3-4E7A-A46B-5B3F45E45746Q35752577-FF0E9C29-EDFA-48BC-AD86-08C51C401CE4Q36303574-030A49F6-D8DE-4A2F-AA2E-530131F554EBQ37385029-B313C761-5CCD-4061-8DB8-4E7D5F862C97Q37512952-6015FA64-4715-4ABF-A512-B736039C39F7Q38917583-E8C3BF6B-CE49-4C90-86BC-DBE60C630542Q39603891-A462CA19-DD3D-4BAA-80CA-5299F02753F8Q41830403-C5326FA7-3E7E-41CC-BB97-D57F470B3680Q43006628-06311C25-5703-4603-849C-15228F93F05CQ49300222-D21AB63A-B6A7-4642-8B14-0948CDF8137BQ50505059-82CB08CE-AD8A-4C33-A10F-A45904910C48Q58691387-3313340B-9256-4246-9C68-DD6CAB5FBE11
P2860
Enzymatic mechanism of human apurinic/apyrimidinic endonuclease against a THF AP site model substrate.
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on January 2009
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
@da
vědecký článek
@cs
name
Enzymatic mechanism of human a ...... a THF AP site model substrate.
@en
Enzymatic mechanism of human a ...... a THF AP site model substrate.
@nl
type
label
Enzymatic mechanism of human a ...... a THF AP site model substrate.
@en
Enzymatic mechanism of human a ...... a THF AP site model substrate.
@nl
prefLabel
Enzymatic mechanism of human a ...... a THF AP site model substrate.
@en
Enzymatic mechanism of human a ...... a THF AP site model substrate.
@nl
P2093
P2860
P356
P1433
P1476
Enzymatic mechanism of human a ...... a THF AP site model substrate.
@en
P2093
James C Delaney
John M Essigmann
Phyllis R Strauss
Sophia T Mundle
P2860
P356
10.1021/BI8016137
P407
P577
2009-01-01T00:00:00Z