Bcl-xL anti-apoptotic network is dispensable for development and maintenance of CML but is required for disease progression where it represents a new therapeutic target.
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ABT-263 induces apoptosis and synergizes with chemotherapy by targeting stemness pathways in esophageal cancer.Genetic events other than BCR-ABL1.Regulation of hematopoietic stem cell integrity through p53 and its related factors.Indole-3-carbinol induces apoptosis of chronic myelogenous leukemia cells through suppression of STAT5 and Akt signaling pathways.High CIP2A levels correlate with an antiapoptotic phenotype that can be overcome by targeting BCL-XL in chronic myeloid leukemia.Cellular and Molecular Networks in Chronic Myeloid Leukemia: The Leukemic Stem, Progenitor and Stromal Cell Interplay.A personalised medicine approach for ponatinib-resistant chronic myeloid leukaemia.Effects of lentivirus mediated STAT3 silencing on human chronic myeloid leukemia cells and leukemia mice.
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Bcl-xL anti-apoptotic network is dispensable for development and maintenance of CML but is required for disease progression where it represents a new therapeutic target.
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article científic
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article scientifique
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articolo scientifico
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artigo científico
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bilimsel makale
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scientific article published on 14 May 2013
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
Bcl-xL anti-apoptotic network ...... ents a new therapeutic target.
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Bcl-xL anti-apoptotic network ...... ents a new therapeutic target.
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type
label
Bcl-xL anti-apoptotic network ...... ents a new therapeutic target.
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Bcl-xL anti-apoptotic network ...... ents a new therapeutic target.
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prefLabel
Bcl-xL anti-apoptotic network ...... ents a new therapeutic target.
@en
Bcl-xL anti-apoptotic network ...... ents a new therapeutic target.
@nl
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Bcl-xL anti-apoptotic network ...... ents a new therapeutic target.
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C J Walker
C S Huettner
D Perrotti
G J Ferenchak
G Marcucci
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10.1038/LEU.2013.151
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2013-05-14T00:00:00Z
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1030067409