Phospholipase C-gamma binds directly to the Na+/H+ exchanger 3 and is required for calcium regulation of exchange activity.
about
Reduced sodium/proton exchanger NHE3 activity causes congenital sodium diarrheaAdaptive GDDA-BLAST: fast and efficient algorithm for protein sequence embeddingGastrin induces sodium-hydrogen exchanger 3 phosphorylation and mTOR activation via a phosphoinositide 3-kinase-/protein kinase C-dependent but AKT-independent pathway in renal proximal tubule cells derived from a normotensive male human.Phosphatidylinositol 4,5-bisphosphate and loss of PLCgamma activity inhibit TRPM channels required for oscillatory Ca2+ signaling.PLC-γ directly binds activated c-Src, which is necessary for carbachol-mediated inhibition of NHE3 activity in Caco-2/BBe cellsNHERF1 and NHERF2 are necessary for multiple but usually separate aspects of basal and acute regulation of NHE3 activity.Effect of acute acid-base disturbances on the phosphorylation of phospholipase C-γ1 and Erk1/2 in the renal proximal tubule.Calmodulin kinase II constitutively binds, phosphorylates, and inhibits brush border Na+/H+ exchanger 3 (NHE3) by a NHERF2 protein-dependent process.Secretory diarrhoea: mechanisms and emerging therapies.Mechanisms of the regulation of the intestinal Na+/H+ exchanger NHE3Carbachol-mediated endocytosis of NHE3 involves a clathrin-independent mechanism requiring lipid rafts and Cdc42.Tyrosine phosphorylation-dependent activation of TRPC6 regulated by PLC-γ1 and nephrin: effect of mutations associated with focal segmental glomerulosclerosis.
P2860
Q28119064-CFC9DE50-F271-448C-ABF6-15B67AD89714Q28475902-35E7295A-0089-42EC-9CBB-52B96B499E46Q30414992-E7AB07D0-3B25-4813-81B2-32BFA4B49D09Q33655594-DD223500-939A-4A66-A127-57943E900BA4Q33816681-EEA1A2C7-B481-4F9A-BEFF-86347106EBEDQ34782190-66D68DD6-B969-417A-9322-B2BEC83E5EBDQ35362968-F7E4F16D-745F-4BB1-836F-219569160009Q35921733-57CD0227-FC5B-4D8A-BFAF-F35BF0A82154Q36673563-9958965F-64E6-4A2D-BF5C-3875465A98E0Q37462304-178F470D-6B48-4968-8961-CB28A375CC73Q40544023-2A559E6A-3199-4303-9020-11AC6456736CQ42133639-32A69F3F-4F41-42D6-B4D6-3875FB6FEDE4
P2860
Phospholipase C-gamma binds directly to the Na+/H+ exchanger 3 and is required for calcium regulation of exchange activity.
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on 27 May 2009
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
@da
vědecký článek
@cs
name
Phospholipase C-gamma binds di ...... gulation of exchange activity.
@en
Phospholipase C-gamma binds di ...... gulation of exchange activity.
@nl
type
label
Phospholipase C-gamma binds di ...... gulation of exchange activity.
@en
Phospholipase C-gamma binds di ...... gulation of exchange activity.
@nl
prefLabel
Phospholipase C-gamma binds di ...... gulation of exchange activity.
@en
Phospholipase C-gamma binds di ...... gulation of exchange activity.
@nl
P2093
P2860
P356
P1476
Phospholipase C-gamma binds di ...... egulation of exchange activity
@en
P2093
Boyoung Cha
Damian B van Rossum
Gabriela Caraveo
Mark Donowitz
Nicholas C Zachos
Rafiquel Sarker
Randen L Patterson
Stephen Desiderio
P2860
P304
19437-19444
P356
10.1074/JBC.M109.006098
P407
P50
P577
2009-05-27T00:00:00Z