Activating transcription factor 4 is translationally regulated by hypoxic stress.
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Hypoxia induces a functionally significant and translationally efficient neuronal NO synthase mRNA variantGene expression during acute and prolonged hypoxia is regulated by distinct mechanisms of translational control.Endoplasmic reticulum protein BI-1 modulates unfolded protein response signaling and protects against stroke and traumatic brain injuryEndoplasmic reticulum stress: cell life and death decisions.Hypoxia inhibits protein synthesis through a 4E-BP1 and elongation factor 2 kinase pathway controlled by mTOR and uncoupled in breast cancer cellsAlphaherpesvirus Subversion of Stress-Induced Translational ArrestHypoxia signaling pathways: modulators of oxygen-related organellesAntioxidant responses and cellular adjustments to oxidative stressGene expression regulation by upstream open reading frames and human diseaseThe Role of the PERK/eIF2α/ATF4/CHOP Signaling Pathway in Tumor Progression During Endoplasmic Reticulum StressTumor progression and the different faces of the PERK kinaseInflammation and cellular stress: a mechanistic link between immune-mediated and metabolically driven pathologiesThe ERAD inhibitor Eeyarestatin I is a bifunctional compound with a membrane-binding domain and a p97/VCP inhibitory groupMethamphetamine induces dopamine D1 receptor-dependent endoplasmic reticulum stress-related molecular events in the rat striatumAberrant, differential and bidirectional regulation of the unfolded protein response towards cell survival by 3'-deoxyadenosineAn initial blueprint for myogenic differentiationA molecular neuroethological approach for identifying and characterizing a cascade of behaviorally regulated genesNuclear DISC1 regulates CRE-mediated gene transcription and sleep homeostasis in the fruit fly.Limited effects of an eIF2αS51A allele on neurological impairments in the 5xFAD mouse model of Alzheimer's disease.Molecular pathway of near-infrared laser phototoxicity involves ATF-4 orchestrated ER stressFibrotic myofibroblasts manifest genome-wide derangements of translational controlSmall-molecule inhibitors of HIF-2a translation link its 5'UTR iron-responsive element to oxygen sensing.Translational reprogramming following UVB irradiation is mediated by DNA-PKcs and allows selective recruitment to the polysomes of mRNAs encoding DNA repair enzymes.The unfolded protein response protects human tumor cells during hypoxia through regulation of the autophagy genes MAP1LC3B and ATG5.Reduced changes in protein compared to mRNA levels across non-proliferating tissuesCirculating tumour cells demonstrate an altered response to hypoxia and an aggressive phenotype.Nonsense-mediated RNA decay regulation by cellular stress: implications for tumorigenesis.Structural determinants of PERK inhibitor potency and selectivityUPR-inducible miRNAs contribute to stressful situationsOncogenic stress induced by acute hyper-activation of Bcr-Abl leads to cell death upon induction of excessive aerobic glycolysis.Identification and characterization of a potent activator of p53-independent cellular senescence via a small-molecule screen for modifiers of the integrated stress response.Autoregulation of ribosome biosynthesis by a translational response in fission yeast.Genome-wide analysis of transcript abundance and translation in Arabidopsis seedlings subjected to oxygen deprivationHypoxia. 2. Hypoxia regulates cellular metabolismStress-induced translation of ATF5 mRNA is regulated by the 5'-untranslated region.Hypoxia-induced energy stress regulates mRNA translation and cell growth.eIF2alpha kinases GCN2 and PERK modulate transcription and translation of distinct sets of mRNAs in mouse liver.Perk-dependent translational regulation promotes tumor cell adaptation and angiogenesis in response to hypoxic stress.Hypoxia-induced gene expression results from selective mRNA partitioning to the endoplasmic reticulum.Activating transcription factor 4 promotes angiogenesis of breast cancer through enhanced macrophage recruitment.
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Activating transcription factor 4 is translationally regulated by hypoxic stress.
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on September 2004
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
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vědecký článek
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name
Activating transcription factor 4 is translationally regulated by hypoxic stress.
@en
Activating transcription factor 4 is translationally regulated by hypoxic stress.
@nl
type
label
Activating transcription factor 4 is translationally regulated by hypoxic stress.
@en
Activating transcription factor 4 is translationally regulated by hypoxic stress.
@nl
prefLabel
Activating transcription factor 4 is translationally regulated by hypoxic stress.
@en
Activating transcription factor 4 is translationally regulated by hypoxic stress.
@nl
P2093
P2860
P50
P1476
Activating transcription factor 4 is translationally regulated by hypoxic stress.
@en
P2093
Jaime D Blais
Vasilisa Filipenko
P2860
P304
P356
10.1128/MCB.24.17.7469-7482.2004
P407
P577
2004-09-01T00:00:00Z