Genome mining in Streptomyces avermitilis: A biochemical Baeyer-Villiger reaction and discovery of a new branch of the pentalenolactone family tree.
about
Genome mining in Streptomyces. Elucidation of the role of Baeyer-Villiger monooxygenases and non-heme iron-dependent dehydrogenase/oxygenases in the final steps of the biosynthesis of pentalenolactone and neopentalenolactoneGenome mining in streptomyces. Discovery of an unprecedented P450-catalyzed oxidative rearrangement that is the final step in the biosynthesis of pentalenolactonePentalenic acid is a shunt metabolite in the biosynthesis of the pentalenolactone family of metabolites: hydroxylation of 1-deoxypentalenic acid mediated by CYP105D7 (SAV_7469) of Streptomyces avermitilisFlavoenzymes: versatile catalysts in biosynthetic pathwaysCloning and characterization of the ravidomycin and chrysomycin biosynthetic gene clustersBiochemical characterization of a novel indole prenyltransferase from Streptomyces sp. SN-593Natural products version 2.0: connecting genes to molecules.Baeyer-Villiger C-C bond cleavage reaction in gilvocarcin and jadomycin biosynthesisGenomic basis for natural product biosynthetic diversity in the actinomycetesTerpene synthases are widely distributed in bacteria.Product-mediated regulation of pentalenolactone biosynthesis in Streptomyces species by the MarR/SlyA family activators PenR and PntR.Engineered Streptomyces avermitilis host for heterologous expression of biosynthetic gene cluster for secondary metabolitesExploration and mining of the bacterial terpenome.Genome engineering in actinomycetes using site-specific recombinases.Genome mining of the Streptomyces avermitilis genome and development of genome-minimized hosts for heterologous expression of biosynthetic gene clusters.Ester coupling reactions--an enduring challenge in the chemical synthesis of bioactive natural products.Cloning, expression and characterization of a versatile Baeyer-Villiger monooxygenase from Dietzia sp. D5.The Cytochrome P450-Catalyzed Oxidative Rearrangement in the Final Step of Pentalenolactone Biosynthesis: Substrate Structure Determines MechanismStructure-function analyses of cytochrome P450revI involved in reveromycin A biosynthesis and evaluation of the biological activity of its substrate, reveromycin T.Substitution of a Single Amino Acid Reverses the Regiospecificity of the Baeyer-Villiger Monooxygenase PntE in the Biosynthesis of the Antibiotic Pentalenolactone.Characterization and analysis of an industrial strain of Streptomyces bingchenggensis by genome sequencing and gene microarray.Herpetopanone, a diterpene from Herpetosiphon aurantiacus discovered by isotope labeling.Expansion of chemical space for natural products by uncommon P450 reactions.Recent examples of α-ketoglutarate-dependent mononuclear non-haem iron enzymes in natural product biosynthesesDiscovery, application and protein engineering of Baeyer–Villiger monooxygenases for organic synthesis
P2860
Q24606066-92DD8C79-2D38-43F9-B76D-50A914575A3EQ24618792-709AAA7F-F476-4400-B92A-07657E4AC012Q24632747-FEEDC016-5D9D-4CE3-8D09-B3405834B826Q27022878-3EDBA5C7-9EB8-471D-A602-471B895E3C55Q33530183-CB6299EB-7E67-400C-A99F-63C488088484Q33876903-B51DA2F6-5AB7-4D1D-8EC5-6A44631CB9B1Q34096062-23356F05-45BB-4F10-B8C6-FFC004BCC219Q34308419-331B81A8-5284-432C-8891-5A6EFF8ACCE5Q34711979-FDD0172F-5839-4B38-8897-55DBA5E66C63Q35031386-BD414D08-7AA6-4437-B06D-B71CD65641C5Q36667432-67073DC5-CD9C-4E9E-9906-9C3F771522C6Q37599348-B97332D1-26F5-4018-B9BB-DCF65BC6F17BQ37951089-4F2126F4-B0C9-475C-AE3D-19E526FE69C1Q38098862-10F0AB22-95B5-49E7-AF45-D38F22F4C632Q38132682-B4A055E2-91AE-4640-B2C3-4C5A9A8CDC85Q38311744-D1FE2F50-A2D2-49E8-8C1C-69F226723B44Q40551046-01133463-7464-48DB-906D-328B6F1D2F10Q41674537-78997C3C-2F02-4A62-AA45-DDA97B666737Q42116824-00F3240D-B3DB-4B6F-AE89-DFE69CABC79CQ45901112-37DF52CF-01C4-48E9-A87D-C77DBDA82F25Q46676420-7A23A14E-318C-4960-A6BB-44BA86DC107BQ47120521-63B95D88-6CAA-4991-B9C8-F2EC68D5CFE0Q47996749-8510B5F6-0A1F-4EED-88A5-96C9DDEB6B8FQ57169314-47B6D47A-CEB9-41B8-9A17-7767561ACC0FQ57189249-97FAD735-C4CC-4324-BEA4-B92EA7EB7DB6
P2860
Genome mining in Streptomyces avermitilis: A biochemical Baeyer-Villiger reaction and discovery of a new branch of the pentalenolactone family tree.
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on July 2009
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
@da
vědecký článek
@cs
name
Genome mining in Streptomyces ...... pentalenolactone family tree.
@en
Genome mining in Streptomyces ...... pentalenolactone family tree.
@nl
type
label
Genome mining in Streptomyces ...... pentalenolactone family tree.
@en
Genome mining in Streptomyces ...... pentalenolactone family tree.
@nl
prefLabel
Genome mining in Streptomyces ...... pentalenolactone family tree.
@en
Genome mining in Streptomyces ...... pentalenolactone family tree.
@nl
P2093
P2860
P356
P1433
P1476
Genome mining in Streptomyces ...... pentalenolactone family tree.
@en
P2093
Charles N Tetzlaff
David E Cane
Haruo Ikeda
Jiaoyang Jiang
Mamoru Komatsu
Masato Iwatsuki
P2860
P304
P356
10.1021/BI900766W
P407
P577
2009-07-01T00:00:00Z