HINT1 protein cooperates with cannabinoid 1 receptor to negatively regulate glutamate NMDA receptor activity.
about
The cannabinoid receptor 1 associates with NMDA receptors to produce glutamatergic hypofunction: implications in psychosis and schizophrenia.Hint1 gene deficiency enhances the supraspinal nociceptive sensitivity in mice.Increased PKC activity and altered GSK3β/NMDAR function drive behavior cycling in HINT1-deficient mice: bipolarity or opposing forces.The ON:OFF switch, σ1R-HINT1 protein, controls GPCR-NMDA receptor cross-regulation: implications in neurological disorders.The Sigma-1 Receptor Antagonist, S1RA, Reduces Stroke Damage, Ameliorates Post-Stroke Neurological Deficits and Suppresses the Overexpression of MMP-9.Cannabinoids: Glutamatergic Transmission and Kynurenines.Interactions between the Kynurenine and the Endocannabinoid System with Special Emphasis on MigraineEndocannabinoid control of glutamate NMDA receptors: the therapeutic potential and consequences of dysfunction.Social isolation induces schizophrenia-like behavior potentially associated with HINT1, NMDA receptor 1, and dopamine receptor 2.The σ1 receptor engages the redox-regulated HINT1 protein to bring opioid analgesia under NMDA receptor negative control.HINT1 in Neuropsychiatric Diseases: A Potential Neuroplastic Mediator.Schizophrenia and depression, two poles of endocannabinoid system deregulation.The Role of HINT1 in Methamphetamine-Induced Conditioned Place Preference.Cannabinoid-glutamate interactions in the regulation of food intake in neonatal layer- type chicks: role of glutamate NMDA and AMPA receptors.The calcium-sensitive Sigma-1 receptor prevents cannabinoids from provoking glutamate NMDA receptor hypofunction: implications in antinociception and psychotic diseases.Cannabinoid Receptors and the Endocannabinoid System: Signaling and Function in the Central Nervous System.Fenfluramine diminishes NMDA receptor-mediated seizures via its mixed activity at serotonin 5HT2A and type 1 sigma receptors.
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P2860
HINT1 protein cooperates with cannabinoid 1 receptor to negatively regulate glutamate NMDA receptor activity.
description
article científic
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article scientifique
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articolo scientifico
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artigo científico
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bilimsel makale
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scientific article published on 05 October 2013
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
HINT1 protein cooperates with ...... tamate NMDA receptor activity.
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HINT1 protein cooperates with ...... tamate NMDA receptor activity.
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type
label
HINT1 protein cooperates with ...... tamate NMDA receptor activity.
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HINT1 protein cooperates with ...... tamate NMDA receptor activity.
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HINT1 protein cooperates with ...... tamate NMDA receptor activity.
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HINT1 protein cooperates with ...... tamate NMDA receptor activity.
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HINT1 protein cooperates with ...... tamate NMDA receptor activity.
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Ana Vicente-Sánchez
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10.1186/1756-6606-6-42
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2013-10-05T00:00:00Z
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1002488801