The ubiquitin ligase CRL2ZYG11 targets cyclin B1 for degradation in a conserved pathway that facilitates mitotic slippage.
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Slip slidin' away of mitosis with CRL2Zyg11.Proteomic analysis of cell cycle progression in asynchronous cultures, including mitotic subphases, using PRIMMUS.ZFP36L2 is a cell cycle-regulated CCCH protein necessary for DNA lesion-induced S-phase arrest.ATP depletion during mitotic arrest induces mitotic slippage and APC/CCdh1-dependent cyclin B1 degradation.Addressing a weakness of anticancer therapy with mitosis inhibitors: Mitotic slippage.
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The ubiquitin ligase CRL2ZYG11 targets cyclin B1 for degradation in a conserved pathway that facilitates mitotic slippage.
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bilimsel makale
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scientific article published on 17 October 2016
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The ubiquitin ligase CRL2ZYG11 ...... facilitates mitotic slippage.
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The ubiquitin ligase CRL2ZYG11 ...... facilitates mitotic slippage.
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type
label
The ubiquitin ligase CRL2ZYG11 ...... facilitates mitotic slippage.
@en
The ubiquitin ligase CRL2ZYG11 ...... facilitates mitotic slippage.
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prefLabel
The ubiquitin ligase CRL2ZYG11 ...... facilitates mitotic slippage.
@en
The ubiquitin ligase CRL2ZYG11 ...... facilitates mitotic slippage.
@nl
P2093
P2860
P50
P356
P1476
The ubiquitin ligase CRL2ZYG11 ...... t facilitates mitotic slippage
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P2093
Cassandra S Heighington
David L Owen
Edward T Kipreos
James W Anderson
Natalia G Starostina
Riju S Balachandran
Srividya Vasudevan
P2860
P304
P356
10.1083/JCB.201601083
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P50
P577
2016-10-17T00:00:00Z