Molecular structure of double-minute chromosomes bearing amplified copies of the epidermal growth factor receptor gene in gliomas.
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Amplification and overexpression of the ID4 gene at 6p22.3 in bladder cancer.Architectures of somatic genomic rearrangement in human cancer amplicons at sequence-level resolutionA mechanism of gene amplification driven by small DNA fragments.On the mechanism of gene amplification induced under stress in Escherichia coliClassification of human cancers based on DNA copy number amplification modelingTargeted therapy resistance mediated by dynamic regulation of extrachromosomal mutant EGFR DNA.Relationships linking amplification level to gene over-expression in gliomasAlterations in DNA replication and histone levels promote histone gene amplification in Saccharomyces cerevisiae.Genomic organization and evolution of double minutes/homogeneously staining regions with MYC amplification in human cancer.Small Circular DNAs in Human Pathology.Amplicon rearrangements during the extrachromosomal and intrachromosomal amplification process in a gliomaConstitutive ERK1/2 activation contributes to production of double minute chromosomes in tumour cellsNovel role for non-homologous end joining in the formation of double minutes in methotrexate-resistant colon cancer cells.Extrachromosomal circular DNA is common in yeastParadoxical relationship between the degree of EGFR amplification and outcome in glioblastomas.Erlotinib and the Risk of Oral Cancer: The Erlotinib Prevention of Oral Cancer (EPOC) Randomized Clinical Trial.A survey of intragenic breakpoints in glioblastoma identifies a distinct subset associated with poor survival.De novo-generated small palindromes are characteristic of amplicon boundary junction of double minutes.Characterization at nucleotide resolution of the homogeneously staining region sites of insertion in two cancer cell lines.Triple negative breast carcinoma EGFR amplification is not associated with EGFR, Kras or ALK mutationsPaediatric and adult glioblastoma: multiform (epi)genomic culprits emerge.Peptide vaccines for the treatment of glioblastoma.Genomic discoveries in adult astrocytomaCancer quasispecies and stem-like adaptive aneuploidy.Genome position and gene amplificationEGFRvIII gene rearrangement is an early event in glioblastoma tumorigenesis and expression defines a hierarchy modulated by epigenetic mechanisms.Tyrosine kinase inhibitor resistance in chronic myeloid leukemia cell lines: investigating resistance pathways.Molecular characterization of cell-free eccDNAs in human plasma.Diverse mechanisms of somatic structural variations in human cancer genomes.Extrachromosomal driver mutations in glioblastoma and low-grade glioma.Double minute amplification of mutant PDGF receptor α in a mouse glioma model.Transportin mediates nuclear entry of DNA in vertebrate systems.Targeting a glioblastoma cancer stem-cell population defined by EGF receptor variant III.Double minute chromosomes in glioblastoma multiforme are revealed by precise reconstruction of oncogenic amplicons.Intragenic breakpoint: a marker of genome instability in glioblastoma.Discoveries of Extrachromosomal Circles of DNA in Normal and Tumor Cells.New pattern of EGFR amplification in glioblastoma and the relationship of gene copy number with gene expression profile.Extrachromosomal circular DNA-based amplification and transmission of herbicide resistance in crop weed Amaranthus palmeri.Genome-wide Purification of Extrachromosomal Circular DNA from Eukaryotic Cells.Association of germline or somatic TP53 missense mutation with oncogene amplification in tumors developed in patients with Li-Fraumeni or Li-Fraumeni-like syndrome.
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Molecular structure of double-minute chromosomes bearing amplified copies of the epidermal growth factor receptor gene in gliomas.
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on 21 July 2004
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
@da
vědecký článek
@cs
name
Molecular structure of double- ...... ctor receptor gene in gliomas.
@en
Molecular structure of double- ...... ctor receptor gene in gliomas.
@nl
type
label
Molecular structure of double- ...... ctor receptor gene in gliomas.
@en
Molecular structure of double- ...... ctor receptor gene in gliomas.
@nl
prefLabel
Molecular structure of double- ...... ctor receptor gene in gliomas.
@en
Molecular structure of double- ...... ctor receptor gene in gliomas.
@nl
P2093
P2860
P356
P1476
Molecular structure of double- ...... ctor receptor gene in gliomas.
@en
P2093
Andrej Cör
Anne-Marie Dutrillaux
Bernard Dutrillaux
Bernard Malfoy
Françoise Apiou
Marie-France Poupon
Michelle Debatisse
Nicolas Vogt
Pascal Leuraud
Sandrine-Hélène Lefèvre
P2860
P304
11368-11373
P356
10.1073/PNAS.0402979101
P407
P577
2004-07-21T00:00:00Z