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Molecular insights into the biosynthesis of guadinomine: a type III secretion system inhibitorComplexity generation during natural product biosynthesis using redox enzymesStructure-Guided Expansion of the Substrate Range of Methylmalonyl Coenzyme A Synthetase (MatB) of Rhodopseudomonas palustrisRational Control of Polyketide Extender Units by Structure-Based Engineering of a Crotonyl-CoA Carboxylase/Reductase in Antimycin BiosynthesisThe insect pathogen Serratia marcescens Db10 uses a hybrid non-ribosomal peptide synthetase-polyketide synthase to produce the antibiotic althiomycinFormation and characterization of acyl carrier protein-linked polyketide synthase extender units.Genome-wide screening reveals the genetic determinants of an antibiotic insecticide in Bacillus thuringiensis.Clustering of protein domains for functional and evolutionary studiesRecognition of (2S)-aminomalonyl-acyl carrier protein (ACP) and (2R)-hydroxymalonyl-ACP by acyltransferases in zwittermicin A biosynthesisExpanding the fluorine chemistry of living systems using engineered polyketide synthase pathways.Cloning of separate meilingmycin biosynthesis gene clusters by use of acyltransferase-ketoreductase didomain PCR amplificationNatural products version 2.0: connecting genes to molecules.Programming of erythromycin biosynthesis by a modular polyketide synthaseIdentification of a bioactive 51-membered macrolide complex by activation of a silent polyketide synthase in Streptomyces ambofaciens.Identification of the biosynthetic gene cluster for the antibiotic polyketide L-155,175 in Streptomyces hygroscopicus.Biosynthesis of the allylmalonyl-CoA extender unit for the FK506 polyketide synthase proceeds through a dedicated polyketide synthase and facilitates the mutasynthesis of analogues.Engineering polyketide synthases and nonribosomal peptide synthetases.A sea of biosynthesis: marine natural products meet the molecular age.A polyketide synthase acyltransferase domain structure suggests a recognition mechanism for its hydroxymalonyl-acyl carrier protein substrate.Screening and Engineering the Synthetic Potential of Carboxylating Reductases from Central Metabolism and Polyketide Biosynthesis.Production of the Bengamide Class of Marine Natural Products in Myxobacteria: Biosynthesis and Structure-Activity Relationships.Metabolic Interplay between the Asian Citrus Psyllid and Its Profftella Symbiont: An Achilles' Heel of the Citrus Greening Insect Vector.Hijacking a hydroxyethyl unit from a central metabolic ketose into a nonribosomal peptide assembly linePrimordial oil slick and the formation of hydrophobic tetrapyrrole macrocyclesHarnessing natural product assembly lines: structure, promiscuity, and engineering.Structure-based analysis of the molecular interactions between acyltransferase and acyl carrier protein in vicenistatin biosynthesis.Designed biosynthesis of 36-methyl-FK506 by polyketide precursor pathway engineering.Biosynthesis of the salinosporamide A polyketide synthase substrate chloroethylmalonyl-coenzyme A from S-adenosyl-L-methionine.First biosynthetic pathway of 1-hepten-3-one in Iporangaia pustulosa (Opiliones)Biosynthesis of salinosporamides from alpha,beta-unsaturated fatty acids: implications for extending polyketide synthase diversity.Structural analysis of protein-protein interactions in type I polyketide synthasesPolyketide stereocontrol: a study in chemical biology.Engineering the acyltransferase substrate specificity of assembly line polyketide synthases.Biosynthesis of rapamycin and its regulation: past achievements and recent progress.Carboxylases in natural and synthetic microbial pathwaysProtein engineering towards natural product synthesis and diversification.Beyond ethylmalonyl-CoA: the functional role of crotonyl-CoA carboxylase/reductase homologs in expanding polyketide diversity.Synthetic biological approaches to natural product biosynthesis.Stereocontrol within polyketide assembly lines.Recent advances in the biosynthesis of unusual polyketide synthase substrates.
P2860
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P2860
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on January 2009
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
@da
vědecký článek
@cs
name
Biosynthesis of polyketide synthase extender units.
@en
Biosynthesis of polyketide synthase extender units.
@nl
type
label
Biosynthesis of polyketide synthase extender units.
@en
Biosynthesis of polyketide synthase extender units.
@nl
prefLabel
Biosynthesis of polyketide synthase extender units.
@en
Biosynthesis of polyketide synthase extender units.
@nl
P2093
P2860
P356
P1476
Biosynthesis of polyketide synthase extender units.
@en
P2093
Angela M Podevels
Brian M Kevany
Michael G Thomas
Yolande A Chan
P2860
P304
P356
10.1039/B801658P
P577
2009-01-01T00:00:00Z