Evidence for an association between thyroid-stimulating hormone and insulin-like growth factor 1 receptors: a tale of two antigens implicated in Graves' disease.
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Platelet-derived growth factor: a key factor in the pathogenesis of graves' ophthalmopathy and potential target for treatmentCurrent concepts in the molecular pathogenesis of thyroid-associated ophthalmopathy.Graves' ophthalmopathyNuclear targeting of IGF-1 receptor in orbital fibroblasts from Graves' disease: apparent role of ADAM17Increased generation of fibrocytes in thyroid-associated ophthalmopathy.Rationale for therapeutic targeting insulin-like growth factor-1 receptor and bone marrow-derived fibrocytes in thyroid-associated ophthalmopathyImmunopathogenesis of thyroid eye disease: emerging paradigmsUpdate on thyroid-associated Ophthalmopathy with a special emphasis on the ocular surfaceInsulin-like growth factor-I regulation of immune function: a potential therapeutic target in autoimmune diseases?Teprotumumab, an IGF-1R blocking monoclonal antibody inhibits TSH and IGF-1 action in fibrocytes.PI3K/AKT pathway mediates induction of IL-1RA by TSH in fibrocytes: modulation by PTENTeprotumumab for Thyroid-Associated Ophthalmopathy.Bidirectional TSH and IGF-1 receptor cross talk mediates stimulation of hyaluronan secretion by Graves' disease immunoglobinsOrbital fibrosis in a mouse model of Graves' disease induced by genetic immunization of thyrotropin receptor cDNAIndependent adipogenic and contractile properties of fibroblasts in Graves' orbitopathy: an in vitro model for the evaluation of treatments.Rituximab (Rituxan) therapy for severe thyroid-associated ophthalmopathy diminishes IGF-1R(+) T cellsFibroblasts expressing the thyrotropin receptor overarch thyroid and orbit in Graves' disease.TSH-Mediated TNFα Production in Human Fibrocytes Is Inhibited by Teprotumumab, an IGF-1R Antagonist.Graves' ophthalmopathy: a review of immunogenetics.A stimulatory thyrotropin receptor antibody enhances hyaluronic acid synthesis in graves' orbital fibroblasts: inhibition by an IGF-I receptor blocking antibody.Increased expression of TSH receptor by fibrocytes in thyroid-associated ophthalmopathy leads to chemokine production.Human fibrocytes coexpress thyroglobulin and thyrotropin receptorImmunopathogenesis of Graves' ophthalmopathy: the role of the TSH receptor.CD40 Expression in Fibrocytes Is Induced by TSH: Potential Synergistic Immune Activation.Pentraxin-3 Is a TSH-Inducible Protein in Human Fibrocytes and Orbital Fibroblasts.Disrupted TSH Receptor Expression in Female Mouse Lung Fibroblasts Alters Subcellular IGF-1 Receptor Distribution.TSH-receptor-expressing fibrocytes and thyroid-associated ophthalmopathy.Interleukin-6 production in CD40-engaged fibrocytes in thyroid-associated ophthalmopathy: involvement of Akt and NF-κB.The pathophysiology of thyroid eye disease: implications for immunotherapy.Insulin Receptor Substrate 1, the Hub Linking Follicle-stimulating Hormone to Phosphatidylinositol 3-Kinase ActivationLack of Association between Selenium Status and Disease Severity and Activity in Patients with Graves' OphthalmopathyTSH/IGF-1 Receptor Cross Talk in Graves' Ophthalmopathy Pathogenesis.Thyroid antibody-negative euthyroid Graves' ophthalmopathy.Role of insulin-like growth factor-1 (IGF-1) pathway in the pathogenesis of Graves' orbitopathy.Update on advanced imaging options for thyroid-associated orbitopathy.A modified ELISA accurately measures secretion of high molecular weight hyaluronan (HA) by Graves' disease orbital cells.Building the Case for Insulin-Like Growth Factor Receptor-I Involvement in Thyroid-Associated Ophthalmopathy.Graves' orbitopathy: imperfect treatments for a rare disease.Pathogenesis of Graves' orbitopathy: a 2010 update.Potential role for bone marrow-derived fibrocytes in the orbital fibroblast heterogeneity associated with thyroid-associated ophthalmopathy.
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Evidence for an association between thyroid-stimulating hormone and insulin-like growth factor 1 receptors: a tale of two antigens implicated in Graves' disease.
description
article científic
@ca
article scientifique
@fr
articolo scientifico
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artigo científico
@pt
bilimsel makale
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scientific article published on September 2008
@en
vedecký článok
@sk
vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
Evidence for an association be ...... implicated in Graves' disease.
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Evidence for an association be ...... implicated in Graves' disease.
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type
label
Evidence for an association be ...... implicated in Graves' disease.
@en
Evidence for an association be ...... implicated in Graves' disease.
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prefLabel
Evidence for an association be ...... implicated in Graves' disease.
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Evidence for an association be ...... implicated in Graves' disease.
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P2093
P2860
P1476
Evidence for an association be ...... implicated in Graves' disease
@en
P2093
Amiya Sinha Hikim
Andrew G Gianoukakis
Catherine J Hwang
Nikoo F Afifiyan
Shanli Tsui
Terry J Smith
P2860
P304
P356
10.4049/JIMMUNOL.181.6.4397
P407
P577
2008-09-01T00:00:00Z