Integrated genomic analysis identifies recurrent mutations and evolution patterns driving the initiation and progression of follicular lymphoma. - Test2 - elhamkhani - TriplyDB

Integrated genomic analysis identifies recurrent mutations and evolution patterns driving the initiation and progression of follicular lymphoma.

Integrated genomic analysis identifies recurrent mutations and evolution patterns driving the initiation and progression of follicular lymphoma.

http://www.wikidata.org/entity/Q37533656

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Tumour Cell Heterogeneity Is lineage decision-making restricted during tumoral reprograming of haematopoietic stem cells?Mutation of chromatin modifiers; an emerging hallmark of germinal center B-cell lymphomas Deciphering the molecular landscape in chronic lymphocytic leukemia: time frame of disease evolution The epigenetic basis of diffuse large B-cell lymphoma Structural variation discovery in the cancer genome using next generation sequencing: computational solutions and perspectives Every amino acid matters: essential contributions of histone variants to mammalian development and disease Chromatin signatures of cancer Clinical impact of recurrently mutated genes on lymphoma diagnostics: state-of-the-art and beyond Integrative systems medicine approaches to identify molecular targets in lymphoid malignancies Emerging concepts of epigenetic dysregulation in hematological malignancies The European Hematology Association Roadmap for European Hematology Research: a consensus document When to treat patients with relapsed follicular lymphoma.Data on affected cancer-related genes in pediatric t(12;21)-positive acute lymphoblastic leukemia patients harboring unbalanced der(6)t(X;6) translocations.Phase 1 study of the oral histone deacetylase inhibitor abexinostat in patients with Hodgkin lymphoma, non-Hodgkin lymphoma, or chronic lymphocytic leukaemia.Nature and importance of follicular lymphoma precursors.Crebbp loss cooperates with Bcl2 overexpression to promote lymphoma in mice.EZH2 alterations in follicular lymphoma: biological and clinical correlations.DNA methylome analysis in Burkitt and follicular lymphomas identifies differentially methylated regions linked to somatic mutation and transcriptional control.Molecular Testing of Lymphoproliferative Disorders: Current Status and Perspectives.Distinct biological subtypes and patterns of genome evolution in lymphoma revealed by circulating tumor DNA.Frequent disruption of the RB pathway in indolent follicular lymphoma suggests a new combination therapy Intraclonal diversity in follicular lymphoma analyzed by quantitative ultradeep sequencing of noncoding regions Whole-exome sequencing defines the mutational landscape of pheochromocytoma and identifies KMT2D as a recurrently mutated gene Disruption of KMT2D perturbs germinal center B cell development and promotes lymphomagenesis.Sleeping Beauty mouse models identify candidate genes involved in gliomagenesis.BCL2 mutations are associated with increased risk of transformation and shortened survival in follicular lymphoma Polycomb genes, miRNA, and their deregulation in B-cell malignancies Germinal center reentries of BCL2-overexpressing B cells drive follicular lymphoma progression.Mutations in early follicular lymphoma progenitors are associated with suppressed antigen presentation Amplification of 2p as a genomic marker for transformation in lymphoma.High Throughput Sequencing Analysis of the Immunoglobulin Heavy Chain Gene from Flow-Sorted B Cell Sub-Populations Define the Dynamics of Follicular Lymphoma Clonal Evolution.Genetics and Prognostication in Splenic Marginal Zone Lymphoma: Revelations from Deep Sequencing.TET1 is a tumor suppressor of hematopoietic malignancy DNA Methylation and Somatic Mutations Converge on the Cell Cycle and Define Similar Evolutionary Histories in Brain Tumors Histological Transformation and Progression in Follicular Lymphoma: A Clonal Evolution Study.Cell of origin of transformed follicular lymphoma The H1 linker histones: multifunctional proteins beyond the nucleosomal core particle.Emerging role of mutations in epigenetic regulators including MLL2 derived from The Cancer Genome Atlas for cervical cancer.Targeting EZH2 and PRC2 dependence as novel anticancer therapy.

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Integrated genomic analysis identifies recurrent mutations and evolution patterns driving the initiation and progression of follicular lymphoma.

http://www.wikidata.org/entity/Q37533656

description

article científic

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article scientifique

@fr

articolo scientifico

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artigo científico

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bilimsel makale

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scientific article published on 22 December 2013

@en

vedecký článok

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vetenskaplig artikel

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videnskabelig artikel

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vědecký článek

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name

Integrated genomic analysis id ...... ession of follicular lymphoma.

@en

Integrated genomic analysis id ...... ession of follicular lymphoma.

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type

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Integrated genomic analysis id ...... ession of follicular lymphoma.

@en

Integrated genomic analysis id ...... ession of follicular lymphoma.

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prefLabel

Integrated genomic analysis id ...... ession of follicular lymphoma.

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Integrated genomic analysis id ...... ession of follicular lymphoma.

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Nature Genetics

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Integrated genomic analysis id ...... ession of follicular lymphoma.

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Andras Matolcsy

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Andrew Davies

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Andrew Norton

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Cheng-Yuan Yang

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Ciaran O'Riain

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David Wrench

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Derville O'Shea

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Emanuela Carlotti

http://www.w3.org/2001/XMLSchema#string

Georg Lenz

http://www.w3.org/2001/XMLSchema#string

Jacek Marzec

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P2860

DELLY: structural variant discovery by integrated paired-end and split-read analysis

Chronic active B-cell-receptor signalling in diffuse large B-cell lymphoma

VarScan 2: somatic mutation and copy number alteration discovery in cancer by exome sequencing

Frequent mutation of histone-modifying genes in non-Hodgkin lymphoma

Nucleosomes, linker DNA, and linker histone form a unique structural motif that directs the higher-order folding and compaction of chromatin

Fast and accurate short read alignment with Burrows-Wheeler transform

The neighbor-joining method: a new method for reconstructing phylogenetic trees

Structure of an Ebf1:DNA complex reveals unusual DNA recognition and structural homology with Rel proteins

Crystal structure of globular domain of histone H5 and its implications for nucleosome binding

Somatic mutations altering EZH2 (Tyr641) in follicular and diffuse large B-cell lymphomas of germinal-center origin.

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176-181

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scholarly article

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10.1038/NG.2856

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2

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46

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Charles H. Lawrie

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2013-12-22T00:00:00Z

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259449305

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1015438319

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24362818

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3907271

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