about
Structural model of the hUbA1-UbcH10 quaternary complex: in silico and experimental analysis of the protein-protein interactions between E1, E2 and ubiquitinCircular dichroism and thermal melting differentiation of Hoechst 33258 binding to the curved (A(4)T(4)) and straight (T(4)A(4)) DNA sequences.Pyrrolo[1,3]benzothiazepine-based atypical antipsychotic agents. Synthesis, structure-activity relationship, molecular modeling, and biological studies.Neuronal high-affinity sodium-dependent glutamate transporters (EAATs): targets for the development of novel therapeutics against neurodegenerative diseases.Substrate inhibitors and blockers of excitatory amino acid transporters in the treatment of neurodegeneration: critical considerations.Interaction of the N-(3-Methylpyridin-2-yl)amide Derivatives of Flurbiprofen and Ibuprofen with FAAH: Enantiomeric Selectivity and Binding ModeHyodeoxycholic acid derivatives as liver X receptor α and G-protein-coupled bile acid receptor agonists.Peptide Nucleic Acids as miRNA Target Protectors for the Treatment of Cystic Fibrosis.Design and synthesis of potent antimalarial agents based on clotrimazole scaffold: exploring an innovative pharmacophore.Pyrrolo[1,5]benzoxa(thia)zepines as a new class of potent apoptotic agents. Biological studies and identification of an intracellular location of their drug target.Novel atypical antipsychotic agents: rational design, an efficient palladium-catalyzed route, and pharmacological studies.Benzoxepin-derived estrogen receptor modulators: a novel molecular scaffold for the estrogen receptor.Exploitation of a very small peptide nucleic acid as a new inhibitor of miR-509-3p involved in the regulation of cystic fibrosis disease-gene expression.Development of piperazine-tethered heterodimers as potent antimalarials against chloroquine-resistant P. falciparum strains. Synthesis and molecular modeling.Endoperoxide derivatives from marine organisms: 1,2-dioxanes of the plakortin family as novel antimalarial agents.Insight into the mechanism of action of plakortins, simple 1,2-dioxane antimalarials.2'-Deoxy-8-(propyn-1-yl)adenosine-containing oligonucleotides: effects on stability of duplex and quadruplex structures.A rational approach to the design of selective substrates and potent nontransportable inhibitors of the excitatory amino acid transporter EAAC1 (EAAT3). new glutamate and aspartate analogues as potential neuroprotective agents.Synthesis of 5-methylamino-2'-deoxyuridine derivatives.Synthesis and pharmacological evaluation of potent and highly selective D3 receptor ligands: inhibition of cocaine-seeking behavior and the role of dopamine D3/D2 receptors.Oligonucleotides containing an acridine group covalently bonded to the nucleotide flanking the 3'-3' phosphodiester junction for alternate strand triple helix formation.Pyrrolo[1,3]benzothiazepine-based serotonin and dopamine receptor antagonists. Molecular modeling, further structure-activity relationship studies, and identification of novel atypical antipsychotic agents.Specific targeting of peripheral serotonin 5-HT(3) receptors. Synthesis, biological investigation, and structure-activity relationships.Development of molecular probes for the identification of extra interaction sites in the mid-gorge and peripheral sites of butyrylcholinesterase (BuChE). Rational design of novel, selective, and highly potent BuChE inhibitors.Exploiting protein fluctuations at the active-site gorge of human cholinesterases: further optimization of the design strategy to develop extremely potent inhibitors.Specific targeting highly conserved residues in the HIV-1 reverse transcriptase primer grip region. Design, synthesis, and biological evaluation of novel, potent, and broad spectrum NNRTIs with antiviral activity.Novel propanamides as fatty acid amide hydrolase inhibitors.Synthesis and Biological Evaluation of a New Structural Simplified Analogue of cADPR, a Calcium-Mobilizing Secondary Messenger Firstly Isolated from Sea Urchin Eggs.Discovery of Huperzine A−Tacrine Hybrids as Potent Inhibitors of Human Cholinesterases Targeting Their Midgorge Recognition SitesSpecific Targeting of Acetylcholinesterase and Butyrylcholinesterase Recognition Sites. Rational Design of Novel, Selective, and Highly Potent Cholinesterase InhibitorsFull relative stereochemistry assignment and conformational analysis of 13,19-didesmethyl spirolide C via NMR- and molecular modeling-based techniques. A step towards understanding spirolide’s mechanism of actionBenzylamides and piperazinoarylamides of ibuprofen as fatty acid amide hydrolase inhibitorsFeedback inhibition of cAMP effector signaling by a chaperone-assisted ubiquitin system.Exploring the fatty acid amide hydrolase and cyclooxygenase inhibitory properties of novel amide derivatives of ibuprofen
P50
Q21090578-B6B06CE1-EB06-409B-803E-39E78E17A420Q33183734-66EC1325-4F9C-482B-8E63-EB59C4614C67Q34108790-BB668684-EC95-49C8-8855-DC0B7C9D773BQ35061257-D78CC958-9062-4CEB-B8D2-7CED78944D61Q35581556-F97C539F-E617-44D6-86C4-361A4F9A557EQ35840682-617EC0C7-27CA-445E-B340-0FD00A4BD861Q36289268-E8313B23-99D5-4C79-9DCC-8A15AA03F159Q38683313-E27475E5-69A9-4886-990C-82E060881B2EQ40177378-76AEF051-36A5-4157-827F-0008015ECE60Q40405782-18353468-E929-4364-B30A-9740BA5EE6CDQ40446041-BD8FC904-1889-4730-8F53-DBE66C18B0F0Q40499359-98A90DE5-F7C5-46B5-B1DA-66BDBC578E24Q41451941-4F196DA9-7FD6-4FE5-8D0C-40C140AC8420Q41943023-6F45034B-4B3C-438D-A60C-9EDE207F405FQ41944105-FAE6D2C2-8C7E-488D-8E7C-343DDA26005DQ43172216-9EA795EE-643E-4F6D-9405-C1FAF3267875Q43507088-E55D6871-25F4-4B1D-94AF-4B14741FB0CFQ43687227-32EC9A81-3D70-4036-AF81-8867D29C5E5CQ43806923-C552A088-2D08-4EFB-8F93-BC565A98A85CQ44557226-78598A1D-8DD5-475C-9C4D-BC62C763D366Q44622065-FA206BD8-81E7-4660-96FC-30034CAFD274Q44706454-3C8AA811-28BB-4F42-94F4-B086AB83C094Q46020291-FDCBD6DF-41BF-46B5-AF19-68256E5307F1Q46383054-06DD4064-39C3-4D62-B422-7B2BD47E452DQ46596629-92495593-3FDD-4952-AE78-1B9DBF9FFE0FQ46798082-F868F3A8-67BF-479B-A472-889C604020A6Q48796675-D970AD70-7385-4DAC-8FE5-18D3C69E0C0FQ52657779-02C82B5D-CC73-48B9-A5A9-BE04935AE312Q58855778-E81782F0-F90B-4D32-BC7F-B8574755149FQ58855822-0D713965-E6EA-4293-82B3-F44A2D1135B4Q59265483-EB72EE14-5B48-41B4-8210-743604BCB8C9Q61808703-1EE565B9-8121-4E38-8BC0-3C46B794C725Q64997269-FE066436-6307-4126-B39C-776E92EBFE6BQ90571066-DD9F873A-7638-44B2-B5E1-62D8ABDD1625
P50
description
hulumtues
@sq
researcher
@en
wetenschapper
@nl
հետազոտող
@hy
name
Bruno Catalanotti
@ast
Bruno Catalanotti
@en
Bruno Catalanotti
@es
Bruno Catalanotti
@nl
Bruno Catalanotti
@sl
type
label
Bruno Catalanotti
@ast
Bruno Catalanotti
@en
Bruno Catalanotti
@es
Bruno Catalanotti
@nl
Bruno Catalanotti
@sl
prefLabel
Bruno Catalanotti
@ast
Bruno Catalanotti
@en
Bruno Catalanotti
@es
Bruno Catalanotti
@nl
Bruno Catalanotti
@sl
P1053
D-4025-2016
P106
P1153
6603288284
P21
P31
P3829
P496
0000-0002-7532-6959